Yongwang Miao
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View article: Ovariectomy Enhances Carcass Performance and Meat Quality by Modulating Muscle Development and Lipid Metabolism in Wuding Hens
Ovariectomy Enhances Carcass Performance and Meat Quality by Modulating Muscle Development and Lipid Metabolism in Wuding Hens Open
Estrogen is a key regulator of skeletal muscle growth and metabolism in birds, yet its specific roles in female chickens remain poorly defined. To address this gap, we established an estrogen-deficient model by surgically removing the ovar…
View article: Deciphering the regulatory role of ELF5 in buffalo lactation
Deciphering the regulatory role of ELF5 in buffalo lactation Open
E74 Like ETS Transcription Factor 5 (ELF5) has been implicated in milk protein synthesis in various mammals, but its precise roles and mechanisms in buffalo have remained largely unknown. This study successfully isolated and characterized …
View article: Cognitive impairment mediates the association between sarcopenic obesity and daily living ability in the frail older population
Cognitive impairment mediates the association between sarcopenic obesity and daily living ability in the frail older population Open
Sarcopenic obesity is closely related to cognitive impairment and decreased daily living ability. Sarcopenic obesity can affect daily living ability through the mediating effect of cognitive impairment. Therefore, more attention should be …
View article: Molecular Characteristics and Role of Buffalo SREBF2 in Triglyceride and Cholesterol Biosynthesis in Mammary Epithelial Cells
Molecular Characteristics and Role of Buffalo SREBF2 in Triglyceride and Cholesterol Biosynthesis in Mammary Epithelial Cells Open
Background/Objectives: Sterol regulatory element-binding transcription factor 2 (SREBF2) is a key transcription factor involved in regulating cholesterol homeostasis. However, its role in buffalo mammary gland lipid metabolism remains uncl…
View article: Synergistic Regulation of miR‐29c and miR‐106b in Buffalo Mammary Epithelial Cells Orchestrates Milk Protein Synthesis in a PTHLH‐Mediated Fashion
Synergistic Regulation of miR‐29c and miR‐106b in Buffalo Mammary Epithelial Cells Orchestrates Milk Protein Synthesis in a PTHLH‐Mediated Fashion Open
Research has demonstrated that certain microRNAs (miRNAs) play a pivotal role in governing milk protein synthesis in mice and dairy cows. However, there remains a limited understanding of specific miRNAs that regulate milk protein synthesi…
View article: Molecular and Functional Analysis of the Stearoyl-CoA Desaturase (SCD) Gene in Buffalo: Implications for Milk Fat Synthesis
Molecular and Functional Analysis of the Stearoyl-CoA Desaturase (SCD) Gene in Buffalo: Implications for Milk Fat Synthesis Open
The SCD is a rate-limiting enzyme that catalyzes the synthesis of monounsaturated fatty acids (MUFAs) in dairy cows; however, its role in the mammary gland of buffalo is not well understood. In this study, we isolated and characterized the…
View article: LEP Gene Promotes Milk Fat Synthesis via the JAK2-STAT3 and mTOR Signaling Pathways in Buffalo Mammary Epithelial Cells
LEP Gene Promotes Milk Fat Synthesis via the JAK2-STAT3 and mTOR Signaling Pathways in Buffalo Mammary Epithelial Cells Open
Leptin (LEP), a protein hormone well-known for its role in metabolic regulation, has recently been linked to lipid metabolism in cattle. However, its function in buffalo mammary glands remains unclear. To address this issue, we isolated an…
View article: Molecular characterization, function, tissue differential expression, and single-nucleotide polymorphism of buffalo <i>TP53</i> gene
Molecular characterization, function, tissue differential expression, and single-nucleotide polymorphism of buffalo <i>TP53</i> gene Open
TP53 has been shown to be involved in lactation in cattle. However, the role of TP53 in buffalo lactation remains unknown. To this end, we isolated and identified the complete coding sequence (CDS) of the TP53 gene from the buffalo mammary…
View article: Molecular Characteristics and Polymorphisms of Buffalo (Bubalus bubalis) ABCG2 Gene and Its Role in Milk Fat Synthesis
Molecular Characteristics and Polymorphisms of Buffalo (Bubalus bubalis) ABCG2 Gene and Its Role in Milk Fat Synthesis Open
The ATP-binding cassette subfamily G member 2 (ABCG2) serves crucial roles in secreting riboflavin and biotin vitamins into the milk of cattle, mice, and humans, as well as in the transportation of xenotoxic and cytostatic drugs across the…
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
Milk protein is a key quality indicator of milk, so elucidating its synthesis mechanism has been the focus of research in recent years. Studies have shown that both miRNAs and mRNA genes play important roles in the regulation of milk prote…
View article: CEBPA-Regulated Expression of SOCS1 Suppresses Milk Protein Synthesis through mTOR and JAK2-STAT5 Signaling Pathways in Buffalo Mammary Epithelial Cells
CEBPA-Regulated Expression of SOCS1 Suppresses Milk Protein Synthesis through mTOR and JAK2-STAT5 Signaling Pathways in Buffalo Mammary Epithelial Cells Open
Milk protein content is a key quality indicator of milk, and therefore elucidating its synthesis mechanism has been the focus of research in recent years. Suppressor of cytokine signaling 1 (SOCS1) is an important inhibitor of cytokine sig…
View article: Genome-wide identification of long noncoding RNA genes and their potential association with mammary gland development in water buffalo
Genome-wide identification of long noncoding RNA genes and their potential association with mammary gland development in water buffalo Open
Objective: Water buffalo, an important domestic animal in tropical and subtropical regions, play an important role in agricultural economy. It is an important source for milk, meat, horns, skin, and draft power, especially its rich milk th…
View article: Identification and characterization of alternative splicing variants of buffalo LXRα expressed in mammary gland
Identification and characterization of alternative splicing variants of buffalo LXRα expressed in mammary gland Open
View article: PRESERVATIVE EFFECT OF DIETARY OREGANO AND GERMANDER ON QUALITY AND STORAGE STABILITY OF RAW BROILER MEAT
PRESERVATIVE EFFECT OF DIETARY OREGANO AND GERMANDER ON QUALITY AND STORAGE STABILITY OF RAW BROILER MEAT Open
The effects of dietary Origanum syriacum L. and Teucrium polium L., alone and in combination, on the quality and stability of raw broiler meat were evaluated. Broilers (N=140 ) were reared for 21 days, divided into five groups under comple…
View article: LPIN1 promotes triglycerides synthesis and is transcriptionally regulated by PPARG in buffalo mammary epithelial cells
LPIN1 promotes triglycerides synthesis and is transcriptionally regulated by PPARG in buffalo mammary epithelial cells Open
Studies on 3T3-L1 cells and HepG2 hepatocytes have shown that phosphatidic acid phosphohydrolase1 (LPIN1) plays a key role in adipogenesis, acting as a co-activator of peroxisome proliferator-activated receptor gamma coactivator 1a (PGC-1a…
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
They are supplementary materials to the manuscript and are mainly the result of transcriptome data.
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
They are additional files to the manuscript and are mainly the result of transcriptome data.
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
They are additional files to the manuscript and are mainly the result of transcriptome data.
View article: SOCS1 suppresses milk protein synthesis through mTOR and JAK2-STAT5 signaling pathways and its expression is directly regulated by CEBPA in buffalo mammary epithelial cells
SOCS1 suppresses milk protein synthesis through mTOR and JAK2-STAT5 signaling pathways and its expression is directly regulated by CEBPA in buffalo mammary epithelial cells Open
Supplementary materials
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
Statistics of length distribution of sRNA fragments and co-expression analysis of miRNAs and target mRNAs (docx). Small RNA sequences, primer information and transcriptome data (XLSX)
View article: MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells
MiR-190a regulates milk protein biosynthesis through the mTOR and JAK2–STAT5 signaling pathways by targeting PTHLH in buffalo mammary epithelial cells Open
Statistics of length distribution of sRNA fragments and co-expression analysis of miRNAs and target mRNAs (docx). Small RNA sequences, primer information and transcriptome data (XLSX)
View article: Molecular cloning, functional characterization, tissue expression and polymorphism analysis of buffalo PRDX6 gene
Molecular cloning, functional characterization, tissue expression and polymorphism analysis of buffalo PRDX6 gene Open
PRDX6 is a bifunctional protein involved in antioxidant regulation and phospholipid metabolism. Previous studies have shown that PRDX6 is involved in some biological pathways and networks related to lactation. The aim of this study was to …
View article: Identification, Molecular Characterization, and Tissue Expression Profiles of Three Smad Genes from Water Buffalo (Bubalus bubalis)
Identification, Molecular Characterization, and Tissue Expression Profiles of Three Smad Genes from Water Buffalo (Bubalus bubalis) Open
Smads are involved in a variety of biological activities by mediating bone morphogenetic protein (BMP) signals. The full-length coding sequences (CDSs) of buffalo Smads 1, 4, and 5 were isolated and identified through RT-PCR in this study.…
View article: Liver X receptor α promotes milk fat synthesis in buffalo mammary epithelial cells by regulating the expression of FASN
Liver X receptor α promotes milk fat synthesis in buffalo mammary epithelial cells by regulating the expression of FASN Open
Liver X receptor α (LXRα; NR1H3) is an important transcription factor that can facilitate milk fat synthesis by regulating the transcription of FASN in mice and goats. Nevertheless, the lipid synthesis related to LXRα and its regulation on…
View article: Supplementary file of Identification, molecular characterization, and tissue expression analysis of three Smad genes from water buffalo (Bubalus bubalis)
Supplementary file of Identification, molecular characterization, and tissue expression analysis of three Smad genes from water buffalo (Bubalus bubalis) Open
Supplementary file of Identification, molecular characterization, and tissue expression analysis of three Smad genes from water buffalo (Bubalus bubalis).
View article: Erratum to: Genomic analyses unveil helmeted guinea fowl (<i>Numida meleagris</i>) domestication in West Africa
Erratum to: Genomic analyses unveil helmeted guinea fowl (<i>Numida meleagris</i>) domestication in West Africa Open
View article: EFFECT OF 25-HYDROXYVITAMIN D3 AND DIVALENT CALCIUM ION SUPPLEMENTATION IN SOWS' DIETS ON TRACE ELEMENTS IN BLOOD AND MILK
EFFECT OF 25-HYDROXYVITAMIN D3 AND DIVALENT CALCIUM ION SUPPLEMENTATION IN SOWS' DIETS ON TRACE ELEMENTS IN BLOOD AND MILK Open
This study is designed to evaluate the effect of 25-hydroxyvitamin D3 (25(OH)D3) and divalent calcium ion (Ca2+) supplementation in sows’ diets on trace elements in blood and milk to assess whether it is beneficial to pig growth or not. A …
View article: Genomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa
Genomic Analyses Unveil Helmeted Guinea Fowl (<i>Numida meleagris</i>) Domestication in West Africa Open
Domestication of the helmeted guinea fowl (HGF; Numida meleagris) in Africa remains elusive. Here we report a high-quality de novo genome assembly for domestic HGF generated by long- and short-reads sequencing together with optical and chr…
View article: Mitochondrial DNA diversity and demographic history of Black-boned chickens in China
Mitochondrial DNA diversity and demographic history of Black-boned chickens in China Open
Black-boned chickens (Gallus domesticus, herein abbreviated BBCs) are well known for their unique appearance and medicinal properties and have a long breeding history in China. However, the genetic diversity and demographic history …
View article: Liver X receptor α promotes milk fat synthesis in buffalo mammary epithelial cells by regulating the expression of FASN
Liver X receptor α promotes milk fat synthesis in buffalo mammary epithelial cells by regulating the expression of FASN Open
Supplementary material