Yongxu Zhou
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View article: Mind–body therapies for sleep disturbances, depression, and anxiety in menopausal women: a systematic review and meta-analysis of randomized controlled trials
Mind–body therapies for sleep disturbances, depression, and anxiety in menopausal women: a systematic review and meta-analysis of randomized controlled trials Open
Background Menopause is frequently accompanied by sleep disturbances, depression, and anxiety, negatively affecting women’s quality of life. While hormone therapy can be effective, safety concerns highlight the need for accessible non-phar…
View article: A novel palmitoylation-based molecular signature reveals COX6A1 as a key regulator in metabolic dysfunction-associated steatotic liver disease
A novel palmitoylation-based molecular signature reveals COX6A1 as a key regulator in metabolic dysfunction-associated steatotic liver disease Open
View article: Association Between Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease: Epidemiological Cross-Sectional Study and Mendelian Randomization Analysis
Association Between Obstructive Sleep Apnea and Non-Alcoholic Fatty Liver Disease: Epidemiological Cross-Sectional Study and Mendelian Randomization Analysis Open
These findings suggest a potential association between OSA and the development of NAFLD. While the results provide preliminary evidence for a link, further longitudinal and interventional studies are needed to clarify causality and inform …
View article: Is dancing an effective intervention for fat loss? A systematic review and meta-analysis of dance interventions on body composition
Is dancing an effective intervention for fat loss? A systematic review and meta-analysis of dance interventions on body composition Open
Objective The systematic review aimed to review the research on the effects of dance interventions, relative to normal lifestyles, on body composition in people with overweight and obesity. Methods 7 databases were searched from their ince…
View article: Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma
Identification of afatinib-associated ADH1B and potential small-molecule drugs targeting ADH1B for hepatocellular carcinoma Open
Background: Afatinib is an irreversible epidermal growth factor receptor tyrosine kinase inhibitor, and it plays a role in hepatocellular carcinoma (LIHC). This study aimed to screen a key gene associated with afatinib and identify its pot…
View article: LINC00665 contributes to cholangiocarcinoma progression by modulating IRF1/PD-L1
LINC00665 contributes to cholangiocarcinoma progression by modulating IRF1/PD-L1 Open
Long noncoding RNAs (lncRNAs) have been shown to play crucial roles in human cancers. However, the underlying biological functions and mechanisms of lncRNAs in cholangiocarcinoma (CCA) remain unclear. Here, we found that LINC00665 expressi…
View article: Supplementary Table 1 from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
Supplementary Table 1 from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star Open
Supplementary Table 1: Exosomal ncRNAs involved in cell-to-cell communication in cholangiocarcinoma (CCA)
View article: Data from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
Data from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star Open
Hepatobiliary cancers are a heterogeneous group of malignancies with a dismal prognosis. Despite intensive research efforts focused on these tumors, methods for early diagnosis and effective targeted therapies are still lacking. Exosomes, …
View article: Supplementary Table 1 from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
Supplementary Table 1 from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star Open
Supplementary Table 1: Exosomal ncRNAs involved in cell-to-cell communication in cholangiocarcinoma (CCA)
View article: Data from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
Data from Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star Open
Hepatobiliary cancers are a heterogeneous group of malignancies with a dismal prognosis. Despite intensive research efforts focused on these tumors, methods for early diagnosis and effective targeted therapies are still lacking. Exosomes, …
View article: RPNs Levels Are Prognostic and Diagnostic Markers for Hepatocellular Carcinoma
RPNs Levels Are Prognostic and Diagnostic Markers for Hepatocellular Carcinoma Open
The ribophorin family (RPN) is an essential regulatory subunit of the proteasome. By influencing the ubiquitin-proteasome system activity, ribophorins (RPNs) are responsible for almost all physiology and pathology processes of mammalian ce…
View article: Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer
Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer Open
Inositol 1,4,5-Triphosphate Receptor Family (ITPRs) are necessary intracellular Ca2+-release channel encoders and participate in mammalian cell physiological and pathological processes. Previous studies have suggested that ITPRs participat…
View article: Tumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment
Tumor-associated Exosomes Are Involved in Hepatocellular Carcinoma Tumorigenesis, Diagnosis, and Treatment Open
Hepatocellular carcinoma (HCC) has become a challenging disease worldwide. There are still limitations in the diagnosis and treatment of HCC, and its high metastatic capacity and high recurrence rate are the main reasons for its poor progn…
View article: RPNs Levels are Prognostic and Diagnostic Markers for Hepatocellular Carcinoma
RPNs Levels are Prognostic and Diagnostic Markers for Hepatocellular Carcinoma Open
Background: Ribophorin family (RPNs) are important regulatory subunits of the proteasome. By influencing Ubiquitin-proteasome system activity, RPNs are responsible for almost all processes of physiology and pathology of mammalian cells. Ne…
View article: RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma
RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma Open
RNA-binding motif protein 10 (RBM10), one of the members of the RNA-binding protein (RBP) family, has a tumor suppressor role in multiple cancers. However, the functional role of RBM10 in lung adenocarcinoma (LUAD) and the underlying molec…
View article: Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star
Exosomal Noncoding RNAs in Hepatobiliary Cancer: A Rising Star Open
Hepatobiliary cancers are a heterogeneous group of malignancies with a dismal prognosis. Despite intensive research efforts focused on these tumors, methods for early diagnosis and effective targeted therapies are still lacking. Exosomes, …
View article: RBM10 Interacts with CTBNNBIP1 and Represses Lung Adenocarcinoma Progression Through the Wnt/β- catenin Pathway
RBM10 Interacts with CTBNNBIP1 and Represses Lung Adenocarcinoma Progression Through the Wnt/β- catenin Pathway Open
Background: RNA-binding motif protein 10 (RBM10), one of the RNA-binding protein (RBP) family, has a tumor suppressor role in various tumors. However, the functional role of RBM10 in lung adenocarcinoma (LUAD) and the molecular mechanism r…
View article: SP1-induced HOXD-AS1 promotes malignant progression of cholangiocarcinoma by regulating miR-520c-3p/MYCN
SP1-induced HOXD-AS1 promotes malignant progression of cholangiocarcinoma by regulating miR-520c-3p/MYCN Open
The purpose of this article is to explore the function and mechanism of HOXD-AS1 in cholangiocarcinoma. TCGA, StarBase and JASPAR were applied to predict the differential expression and molecular mechanism. The qRT-PCR was conducted to det…
View article: Author Correction: Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
Author Correction: Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer Open
View article: JQ-1 Inhibits Colon Cancer Proliferation via Suppressing Wnt/β-Catenin Signaling and miR-21
JQ-1 Inhibits Colon Cancer Proliferation via Suppressing Wnt/β-Catenin Signaling and miR-21 Open
Bromodoamin and extraterminal (BET) protein inhibitors are a novel class of cancer therapeutics. Here we aim to investigate the efficacy and mechanism of JQ-1, a potent BET inhibitor, in colon cancer therapy. JQ-1 was used to treat SW480 c…
View article: Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer
Interleukin-17 promotes angiogenesis by stimulating VEGF production of cancer cells via the STAT3/GIV signaling pathway in non-small-cell lung cancer Open