Yoshikazu Kanno
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View article: Recovery Process of Physical Function and Health-related Quality of Life after Total Knee Arthroplasty
Recovery Process of Physical Function and Health-related Quality of Life after Total Knee Arthroplasty Open
〔目的〕人工膝関節全置換術（TKA）による回復過程を検討するために，身体機能および健康関連QOL（HRQOL）を調査した．〔対象〕TKA術後リハを実施した変形性膝関節症患者40膝とした．〔方法〕身体機能評価にはTimed Up and Go test（TUG），膝伸展筋力，開眼片脚起立時間を測定し，HRQOL評価には準WOMACとSF-36を用いた．〔結果〕身体機能の全項目において術後3ヶ月で有意に改善した．準WOMACの痛みとSF-36の身体機能，体の痛み，全体的健康感，…
View article: Identification of hepatic tamoxifen–DNA adducts in mice: α-(N2-deoxyguanosinyl)tamoxifen and α-(N2-deoxyguanosinyl)tamoxifen N-oxide
Identification of hepatic tamoxifen–DNA adducts in mice: α-(N2-deoxyguanosinyl)tamoxifen and α-(N2-deoxyguanosinyl)tamoxifen N-oxide Open
Tamoxifen-DNA adducts detected in the liver of mice treated with tamoxifen have not yet been identified. In the present study a new type of tamoxifen-DNA adduct, four stereoisomers of alpha-(N:(2)-deoxyguanosinyl)tamoxifen N:-oxide 3'-mono…