Yoshinori Mitamura
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View article: Visual outcomes and anatomical biomarkers of Faricimab for diabetic macular edema in the J-CREST real-world comparison of naïve and treated eyes
Visual outcomes and anatomical biomarkers of Faricimab for diabetic macular edema in the J-CREST real-world comparison of naïve and treated eyes Open
View article: A Case of Vitreous Hemorrhage Possibly Attributable to Retinal Arterial Microaneurysm Following <scp>SARS</scp> ‐ <scp>CoV</scp> ‐2 Vaccination
A Case of Vitreous Hemorrhage Possibly Attributable to Retinal Arterial Microaneurysm Following <span>SARS</span> ‐ <span>CoV</span> ‐2 Vaccination Open
Vitreous hemorrhage caused by a ruptured retinal arterial microaneurysm can occur in patients with diabetic retinopathy after severe acute respiratory syndrome coronavirus 2 vaccination.
View article: Associations between Progression of Retinal Pigment Epithelial and Outer Retinal Atrophy and Choroidal Thickness: A 2-Year observation
Associations between Progression of Retinal Pigment Epithelial and Outer Retinal Atrophy and Choroidal Thickness: A 2-Year observation Open
View article: 6-month outcomes of intravitreal faricimab injection for neovascular age-related macular degeneration and their relationships with clinical findings: a multicentre cohort study from the J-CREST
6-month outcomes of intravitreal faricimab injection for neovascular age-related macular degeneration and their relationships with clinical findings: a multicentre cohort study from the J-CREST Open
Background/aims This study aimed to investigate the outcomes of intravitreal faricimab (IVF) injection for neovascular age-related macular degeneration (nAMD) and their relationships with clinical findings. Methods At 14 sites, we retrospe…
View article: Early prostaglandin E1 treatment improves visual outcomes in central retinal artery occlusion: a retrospective study
Early prostaglandin E1 treatment improves visual outcomes in central retinal artery occlusion: a retrospective study Open
Background Central retinal artery occlusion (CRAO) is a vision-threatening emergency with no established effective treatment. Prostaglandin E 1 (PGE 1 ), known for its vasodilatory and cytoprotective properties, may offer therapeutic benef…
View article: Factors that contribute to loss to follow-up in the medium term after initiation of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in Japanese patients
Factors that contribute to loss to follow-up in the medium term after initiation of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in Japanese patients Open
Purpose To identify time-specific factors associated with loss to follow-up (LTFU) in the early to medium term after initiating anti-vascular endothelial growth factor (VEGF) treatment in patients with neovascular age-related macular degen…
View article: Comparative study of the retinal structure and visual acuity in 7–12-year-old children between children with a history of treatment of retinopathy of prematurity and regressed retinopathy of prematurity: multicenter review of J-CREST
Comparative study of the retinal structure and visual acuity in 7–12-year-old children between children with a history of treatment of retinopathy of prematurity and regressed retinopathy of prematurity: multicenter review of J-CREST Open
Purpose Previous studies have reported the efficacy of photocoagulation (PC) therapy for treating retinopathy of prematurity (ROP); however, its long-term effects on visual function and retinal structure remain unclear. This study compared…
View article: Efficacy of vitrectomy combined with and without cataract surgery for diabetic macular edema: one-year follow-up multi-center study in Japan
Efficacy of vitrectomy combined with and without cataract surgery for diabetic macular edema: one-year follow-up multi-center study in Japan Open
View article: Comparison of Endophthalmitis Rates Between Prefilled Syringes and Standard Vials in Aflibercept Intravitreal Injections: A Retrospective Study in Japan
Comparison of Endophthalmitis Rates Between Prefilled Syringes and Standard Vials in Aflibercept Intravitreal Injections: A Retrospective Study in Japan Open
Background: Bacterial endophthalmitis is a rare but serious complication of intravitreal injections (IVIs). Prefilled syringes have been introduced to reduce contamination risk during drug preparation. However, whether they lower the incid…
View article: The epidemiology of uveitis: comparison of its causes and visual outcomes between three-tiered medical facilities in Ube city
The epidemiology of uveitis: comparison of its causes and visual outcomes between three-tiered medical facilities in Ube city Open
View article: Predictors of Disengagement and Loss to Follow-Up of Intravitreal Injection for Neovascular Age-Related Macular Degeneration in a Real-World Clinical Setting: Post Hoc Analysis of the Multicenter Survey from the Japanese Clinical Retinal Study (J-CREST) Group
Predictors of Disengagement and Loss to Follow-Up of Intravitreal Injection for Neovascular Age-Related Macular Degeneration in a Real-World Clinical Setting: Post Hoc Analysis of the Multicenter Survey from the Japanese Clinical Retinal Study (J-CREST) Group Open
Background/Objectives: In a recent study, we investigated anti-VEGF treatment strategies for three subtypes of neovascular age-related macular degeneration (nAMD)—typical AMD (tAMD), polypoidal choroidal vasculopathy (PCV), and retinal ang…
View article: Dietary intake of whale oil–containing ω‐3 long‐chain polyunsaturated fatty acids attenuates choroidal neovascularization in mice
Dietary intake of whale oil–containing ω‐3 long‐chain polyunsaturated fatty acids attenuates choroidal neovascularization in mice Open
Age‐related macular degeneration (AMD) is a leading cause of blindness in Western and developing countries. Since antivascular endothelial growth factor (VEGF) therapy is available for the regression of choroidal neovascularization (CNV), …
View article: Real-world epidemiology of Uveitis: a retrospective three-tier healthcare facility-based comparison of its causes and visual outcome in Ube-City, Japan
Real-world epidemiology of Uveitis: a retrospective three-tier healthcare facility-based comparison of its causes and visual outcome in Ube-City, Japan Open
This study aimed to conduct a comparative epidemiological survey of uveitis across various healthcare settings and elucidate the clinical characteristics. We conducted a retrospective cross-sectional study in the Ube-City medical region in…
View article: Cystoid macular oedema after flanged intraocular lens scleral fixation using the Yamane technique: a multicentre cohort study
Cystoid macular oedema after flanged intraocular lens scleral fixation using the Yamane technique: a multicentre cohort study Open
This retrospective observational multicentre cohort study compared the rate of postoperative cystoid macular oedema (CME) between two intraocular lens (IOL) scleral fixation (SFIOL) techniques: a flanged IOL fixation technique (Yamane tech…
View article: Factors Affecting Visual Acuity After Anti-Vascular Endothelial Growth Factor Therapy in Neovascular Age-Related Macular Degeneration: A Multicenter Study in Japan
Factors Affecting Visual Acuity After Anti-Vascular Endothelial Growth Factor Therapy in Neovascular Age-Related Macular Degeneration: A Multicenter Study in Japan Open
Background/Objectives: Anti-vascular endothelial growth factor (VEGF) therapy is the first-line treatment for neovascular age-related macular degeneration (nvAMD). While proactive and adequate treatment generally leads to better visual out…
View article: ALTERATION OF TREATMENT CHOICES AND THE VISUAL PROGNOSIS FOR DIABETIC MACULAR EDEMA IN THE ERA OF ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR DRUGS
ALTERATION OF TREATMENT CHOICES AND THE VISUAL PROGNOSIS FOR DIABETIC MACULAR EDEMA IN THE ERA OF ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR DRUGS Open
Purpose: To assess the real-world outcome of best-corrected visual acuity after 2-year intervention for treatment-naive diabetic macular edema since the approval of anti-vascular endothelial growth factor therapy. Methods: A total of 1,780…
View article: Extent of Complete Retinal Pigment Epithelial and Outer Retinal Atrophy with Foveal Center Involvement is Associated with Visual Acuity
Extent of Complete Retinal Pigment Epithelial and Outer Retinal Atrophy with Foveal Center Involvement is Associated with Visual Acuity Open
Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
View article: Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in diabetic macular edema: 2-year results from the Japan subgroup of the phase 3 YOSEMITE trial
Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in diabetic macular edema: 2-year results from the Japan subgroup of the phase 3 YOSEMITE trial Open
Purpose To evaluate the 2-year efficacy, durability, and safety of faricimab in patients with diabetic macular edema (DME) in the YOSEMITE Japan subgroup. Study design YOSEMITE/RHINE (NCT03622580/NCT03622593) subgroup analysis: global, mul…
View article: Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage
Graft cell expansion from hiPSC-RPE strip after transplantation in primate eyes with or without RPE damage Open
View article: Cystoid macular oedema after flanged intraocular lens scleral fixation using the Yamane technique: a multicentre cohort study
Cystoid macular oedema after flanged intraocular lens scleral fixation using the Yamane technique: a multicentre cohort study Open
This retrospective observational multicentre cohort study compared the rate of postoperative cystoid macular oedema (CME) between two intraocular lens (IOL) scleral fixation techniques: a flanged IOL fixation technique (Yamane technique) a…
View article: Drug combination of topical ripasudil and brimonidine enhances neuroprotection in a mouse model of optic nerve injury
Drug combination of topical ripasudil and brimonidine enhances neuroprotection in a mouse model of optic nerve injury Open
Combination of topical ripasudil and brimonidine may enhance RGC protection by modulating multiple signaling pathways in the retina.
View article: A Case of Osteopetrosis with Orbital Inflammation Secondary to Maxillary Osteomyelitis
A Case of Osteopetrosis with Orbital Inflammation Secondary to Maxillary Osteomyelitis Open
Introduction: Osteopetrosis is a rare heritable disorder characterized by increased bone density resulting from osteoclast dysfunction. Major complications include bone fracture, osteomyelitis, anemia, and cranial nerve compr…
View article: A case of acquired esotropia with refraction that shifted to hyperopia due to divergence eye movements
A case of acquired esotropia with refraction that shifted to hyperopia due to divergence eye movements Open
View article: Foveal Thickness Fluctuations in Anti-VEGF Treatment for Central Retinal Vein Occlusion
Foveal Thickness Fluctuations in Anti-VEGF Treatment for Central Retinal Vein Occlusion Open
View article: Alterations in choroidal vascular structures due to serum levels of vascular endothelial growth factor in patients with POEMS syndrome
Alterations in choroidal vascular structures due to serum levels of vascular endothelial growth factor in patients with POEMS syndrome Open
View article: Binocular metamorphopsia in patients with branch retinal vein occlusion: a multi-center study
Binocular metamorphopsia in patients with branch retinal vein occlusion: a multi-center study Open
Purpose The pathology of branch retinal vein occlusion (BRVO), a retinal circulatory disease, is related to monocular metamorphopsia-related vision impairment of the affected eyes, but the association of binocular metamorphopsia in such pa…
View article: Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial
Efficacy, durability, and safety of faricimab with extended dosing up to every 16 weeks in Japanese patients with diabetic macular edema: 1-year results from the Japan subgroup of the phase 3 YOSEMITE trial Open
View article: Estimation of Visual Function Using Deep Learning From Ultra-Widefield Fundus Images of Eyes With Retinitis Pigmentosa
Estimation of Visual Function Using Deep Learning From Ultra-Widefield Fundus Images of Eyes With Retinitis Pigmentosa Open
Importance There is no widespread effective treatment to halt the progression of retinitis pigmentosa. Consequently, adequate assessment and estimation of residual visual function are important clinically. Objective To examine whether deep…
View article: Impact of the COVID-19 Pandemic on Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Japan
Impact of the COVID-19 Pandemic on Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema in Japan Open
Anti-vascular endothelial growth factor (VEGF) therapy for diabetic macular edema (DME) improves visual acuity. However, repeated injections during routine outpatient visits are required to maintain this effect. The recent sudden global ou…
View article: Authors’ comments on “branch retinal vein occlusion post severe acute respiratory syndrome coronavirus 2 vaccination”
Authors’ comments on “branch retinal vein occlusion post severe acute respiratory syndrome coronavirus 2 vaccination” Open