Yosuke Watanabe
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View article: Pediatric Alpha‐Fetoprotein‐Producing Gastric Cancer Presenting With Dysphagia and Multiple Liver Tumors
Pediatric Alpha‐Fetoprotein‐Producing Gastric Cancer Presenting With Dysphagia and Multiple Liver Tumors Open
Background Alpha‐fetoprotein (AFP)‐producing gastric cancer (AFPGC) is resistant to chemotherapy and is associated with poor prognosis. Pediatric gastric cancer has an incidence of 0.02% among gastric cancer patients, with a median surviva…
View article: Fibrosis-4 index can predict improved renal function in acute heart failure with preserved ejection fraction
Fibrosis-4 index can predict improved renal function in acute heart failure with preserved ejection fraction Open
Background Improved renal function (IRF) observed in acute heart failure (AHF) is associated with poor prognosis. Since IRF is linked to renal congestion resulting from inadequate decongestion, predicting IRF could enhance management strat…
View article: Combined Assessment of Skeletal Muscle Area Using Computed Tomography in Elderly Patients with Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Replacement
Combined Assessment of Skeletal Muscle Area Using Computed Tomography in Elderly Patients with Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Replacement Open
The psoas muscle area (PMA) and rectus femoris muscle area (RFMA) have been used to estimate whole-body muscle mass in elderly patients. However, it is unclear whether combining these measurements can improve the predictive ability of trad…
View article: Decreased Homeostasis Model Assessment of β-Cell Function in Patients Without Diabetes Can Predict Future Events in Patients With Cardiovascular Disease
Decreased Homeostasis Model Assessment of β-Cell Function in Patients Without Diabetes Can Predict Future Events in Patients With Cardiovascular Disease Open
Decreased HOMA-β is a significant predictor of adverse cardiovascular events in CVD patients without diabetes. These findings suggest reduced insulin secretion contributes to worse outcomes, underscoring the importance of monitoring HOMA-β…
View article: Elevated eicosapentaenoic acid to arachidonic acid ratio and rapid coronary blood flow restoration in ST-elevation myocardial infarction
Elevated eicosapentaenoic acid to arachidonic acid ratio and rapid coronary blood flow restoration in ST-elevation myocardial infarction Open
View article: Two Cases of Delayed Severe Stenosis after Complete Recanalization by Mechanical Thrombectomy
Two Cases of Delayed Severe Stenosis after Complete Recanalization by Mechanical Thrombectomy Open
Mechanical thrombectomy is a recognized treatment for acute ischemic stroke, but there are instances of delayed stenosis following the procedure. Excessive vessel injury caused due to thrombectomy may lead to delayed stenosis. This report …
View article: Association between carotid plaque progression and persistent endothelial dysfunction in an infarct-related coronary artery in STEMI survivors
Association between carotid plaque progression and persistent endothelial dysfunction in an infarct-related coronary artery in STEMI survivors Open
View article: Rehabilitation for Critical Ill Mechanically Ventilated Patients
Rehabilitation for Critical Ill Mechanically Ventilated Patients Open
View article: Real-time material extrusion volume control system for 3D food printers
Real-time material extrusion volume control system for 3D food printers Open
To achieve high-quality printing with a 3D printer, it is important to set optimal printing parameters. In our research, we have advanced the development of a 3D food printer capable of rendering a variety of food products. Notably, the rh…
View article: Pretransfer Aspirin Administration and Its Impact on Angiographic Outcomes for Patients with ST-Elevation Myocardial Infarction
Pretransfer Aspirin Administration and Its Impact on Angiographic Outcomes for Patients with ST-Elevation Myocardial Infarction Open
Although guidelines recommend early aspirin administration after diagnosis of ST-elevation myocardial infarction (STEMI), the decision of pretransfer aspirin administration is at the discretion of the primary physicians. Therefore, this st…
View article: Non-Destructive Tactile Identification by Piezoelectric Sensing End-Effectors with Physical Reservoir Computing based on Multi-Material Integration
Non-Destructive Tactile Identification by Piezoelectric Sensing End-Effectors with Physical Reservoir Computing based on Multi-Material Integration Open
A computational framework that is extremely fast to learn without a labyrinth of coding is known as physical reservoir computing. This computation inputs some action into a real physical system and obtains an output from the observed nonli…
View article: Real-response Texture Discriminator for Quality Evaluation of Carbonated Beverages
Real-response Texture Discriminator for Quality Evaluation of Carbonated Beverages Open
View article: 3D‐Printed Methane‐Producing Electrodes for Microbial Fuel Cells Developed Using Biogel Ink Containing Live Methanogens and White Charcoal
3D‐Printed Methane‐Producing Electrodes for Microbial Fuel Cells Developed Using Biogel Ink Containing Live Methanogens and White Charcoal Open
Front cover: The cover image features a novel electrode, representing the changing process from CO2 to CH4 by the methanogens embedded in a 3D-printed structure with the custom progressive cavity pump system. The results show increased met…
View article: 3D‐Printed Methane‐Producing Electrodes for Microbial Fuel Cells Developed Using Biogel Ink Containing Live Methanogens and White Charcoal
3D‐Printed Methane‐Producing Electrodes for Microbial Fuel Cells Developed Using Biogel Ink Containing Live Methanogens and White Charcoal Open
Methanogens are used as catalysts for cathodes in microbial fuel cells, to reduce CO 2 to CH 4 . However, the attachment of microbes to the electrodes via culturing is time‐consuming, and inadequate biofilm formation can lead to lesser sur…
View article: 4D Printing of Hydrogels Controlled by Hinge Structure and Spatially Gradient Swelling for Soft Robots
4D Printing of Hydrogels Controlled by Hinge Structure and Spatially Gradient Swelling for Soft Robots Open
In 4D printing, structures with gradients in physical properties are 3D printed in order to dramatically increase deformation. For example, printing bilayer structures with passive and active layers has been proposed, however, these method…
View article: Autonomous mushroom cultivation using a three-dimensional culture medium supported by a 3D printed anisotropic elastic structure
Autonomous mushroom cultivation using a three-dimensional culture medium supported by a 3D printed anisotropic elastic structure Open
Mushrooms grow so fast during the harvest season that they can double in size in a day. However, the soft and fragile nature of mushrooms makes manual harvesting of domestic brand varieties a necessity, and harvest losses frequently occur.…
View article: Development of Vacuum Driven Actuator by Pouch Processing of 3D Printed Bending Structure
Development of Vacuum Driven Actuator by Pouch Processing of 3D Printed Bending Structure Open
There are many polymeric materials that could be introduced as soft actuators, however the choices are actually limited due to strong degradation constraints. Among them, hydrogels have the weakness of drying, although their softness can b…
View article: Physical reservoir computing system with human-like food texture perception
Physical reservoir computing system with human-like food texture perception Open
Although people may have discrepancies in their perception of food texture for the same food depending on the chewing speed and the structure of the oral cavity, we assume that there is no significant variation among individuals in terms o…
View article: Development of a vacuum-pressure-driven actuator ”MORI-U” based on a hollow cube with non-uniform wall thickness that contains a deformation-defining structure by 3D printing
Development of a vacuum-pressure-driven actuator ”MORI-U” based on a hollow cube with non-uniform wall thickness that contains a deformation-defining structure by 3D printing Open
MORI-A FleX is a soft modular robot that can be deformed, reconfigured, and adapted to different environments. However, MORI-A FleX is not versatile because it is currently only actuated by vacuum. Therefore, this study proposes the ”MORI-…
View article: Gel Biter: food texture discriminator based on physical reservoir computing with multiple soft materials
Gel Biter: food texture discriminator based on physical reservoir computing with multiple soft materials Open
The human oral structure contains organs with distinctly different physical properties, such as teeth, gums, and tongues. When food enters the oral cavity, we can recognize the tactile sensation and shape of the object from multiple perspe…
View article: Prognostic Value of Novel Natriuretic Peptide Index After Percutaneous Coronary Intervention
Prognostic Value of Novel Natriuretic Peptide Index After Percutaneous Coronary Intervention Open
Compared with ANP and BNP, the NPI was more effective in predicting future adverse events after PCI.
View article: A Stratified Analysis of the Risk Associated With Low Body Mass Index for Patients After Percutaneous Coronary Intervention
A Stratified Analysis of the Risk Associated With Low Body Mass Index for Patients After Percutaneous Coronary Intervention Open
Underweight patients with several risk factors significantly increased risk after PCI. Furthermore, the risk associated with low BMI was significantly more pronounced for men, individuals aged 60-74 years, and patients with DM or ACS.
View article: Local Discrimination Based on Piezoelectric Sensing in Robots Composed of Soft Matter with Different Physical Properties
Local Discrimination Based on Piezoelectric Sensing in Robots Composed of Soft Matter with Different Physical Properties Open
The coronavirus epidemic has attracted significant attention to the applications of pet robots which can be used to treat and entertain people in their homes. However, pet robots are fabricated using hard materials and it is difficult for …
View article: A Propensity Score Matched Analysis of Statin Effects on Major Adverse Cardiac Events after Percutaneous Coronary Intervention in Patients Over 75 Years Old
A Propensity Score Matched Analysis of Statin Effects on Major Adverse Cardiac Events after Percutaneous Coronary Intervention in Patients Over 75 Years Old Open
Objective In an extremely aging society, it is beneficial to reconsider the value of medical treatment for extremely elderly patients. We therefore focused on the efficacy of statin therapy in extremely elderly patients. This study investi…
View article: MORI-A: Soft Vacuum-Actuated Module With 3D-Printable Deformation Structure
MORI-A: Soft Vacuum-Actuated Module With 3D-Printable Deformation Structure Open
Many soft robots are made of polymeric materials such as silicone, urethane, and gel. These soft matter-based robots can be designed to have soft functionality by controlling the deformation, elastic modulus, and other properties of the fl…
View article: The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation
The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation Open
Background A hallmark of heart failure is cardiac fibrosis, which results from the injury‐induced differentiation response of resident fibroblasts to myofibroblasts that deposit extracellular matrix. During myofibroblast differentiation, f…
View article: Group V Secretory Phospholipase A<sub>2</sub> Regulates Endocytosis of Acetylated LDL by Transcriptional Activation of PGK1 in RAW264.7 Macrophage Cell Line
Group V Secretory Phospholipase A<sub>2</sub> Regulates Endocytosis of Acetylated LDL by Transcriptional Activation of PGK1 in RAW264.7 Macrophage Cell Line Open
Nuclear sPLA2-V binds to the Pgk1 gene promoter region and increases its transcriptional activity. sPLA2-V regulates AcLDL endocytosis through PGK1-Beclin1 in a manner that is independent of its enzymatic activity in …
View article: The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation
The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation Open
Background A hallmark of heart failure is cardiac fibrosis, which results from the injury-induced differentiation response of resident fibroblasts to myofibroblasts that deposit extracellular matrix. During myofibroblast differentiation, f…
View article: Cutoff values of functional status score for the ICU(FSS-ICU) to predict patient discharge in critically ill ICU patients
Cutoff values of functional status score for the ICU(FSS-ICU) to predict patient discharge in critically ill ICU patients Open
【目的】functional status score for the ICU（FSS-ICU）が自宅からICUに入院した本邦の重症患者において，急性期病院から直接自宅退院が可能か否かを予測する因子であるかを確認し，その目安となるカットオフ値を検討することである。【方法】対象は2017年4月1日から2019年3月31日までに，自宅から当院のICUに入室し48時間以上の人工呼吸管理を要した成人とした。調査項目はICU退室時のFSS-ICUおよび当院退院時の自宅退院の可否などを…
View article: Echolucency of carotid plaque is useful for selecting high-risk patients with chronic coronary artery disease who benefit from intensive lipid-lowering therapy
Echolucency of carotid plaque is useful for selecting high-risk patients with chronic coronary artery disease who benefit from intensive lipid-lowering therapy Open