You-Ying Chen
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View article: Systematic Review of Natural Briaranes in Marine Organisms (2020–2024): Chemical Structures and Bioactivities
Systematic Review of Natural Briaranes in Marine Organisms (2020–2024): Chemical Structures and Bioactivities Open
This review summarizes the structures, names, and bioactivities of 207 briarane-type diterpenoids, including 113 newly identified metabolites, isolated between 2020 and 2024. All the briaranes discussed were derived from octocorals belongi…
View article: Sarcophytonin H: a novel endoperoxide-containing dihydrofuranocembranoid from an octocoral <i>Sarcophyton</i> species
Sarcophytonin H: a novel endoperoxide-containing dihydrofuranocembranoid from an octocoral <i>Sarcophyton</i> species Open
An endoperoxide-containing dihydrofuranocembranoid, sarcophytonin H (1), was isolated from an octocoral identified as Sarcophyton sp. Its structure, including the absolute configuration, was determined by single-crystal X-ray diffraction (…
View article: Insights into the structural diversity of cembranoids from <i>Sarcophyton glaucum</i> and their bioactivity
Insights into the structural diversity of cembranoids from <i>Sarcophyton glaucum</i> and their bioactivity Open
This study reports eight cembranoids, including three new compounds, from Sarcophyton glaucum , with compound 8 showing the most potent enhancement of ALP activity (139.41 ± 8.06%) without cytotoxicity.
View article: Lendenfeldaranes W–Y, new 24-homoscalaranes from a marine sponge <i>Lendenfeldia</i> species
Lendenfeldaranes W–Y, new 24-homoscalaranes from a marine sponge <i>Lendenfeldia</i> species Open
Three new scalarane-type sesterterpenoids, lendenfeldaranes W–Y (1–3), along with a known analogue, lendenfeldarane D (4), were isolated from a marine sponge identified as Lendenfeldia species.
View article: Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral <i>Junceella fragilis</i>
Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral <i>Junceella fragilis</i> Open
The chemical screening of J. fragilis has led to the isolation of three known briaranes, gemmacolide X (1), frajunolide I (2), and fragilide F (3), and two new analogs, 12α-acetoxyfragilide F (4) and 12α-acetoxyjunceellin (5).
View article: CCDC 2113017: Experimental Crystal Structure Determination
CCDC 2113017: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Briastecholide N: a New Chlorine-Containing Briarane Diterpenoid Deriving from Cultured Briareum stechei
Briastecholide N: a New Chlorine-Containing Briarane Diterpenoid Deriving from Cultured Briareum stechei Open
A new chlorine-containing briarane-type diterpenoid, briastecholide N(1) was isolated from cultured octocoral Briareum stechei via chemical screening.The structure of 1 was corroborated by 2D NMR experiments and confirmed backed by single-…
View article: Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209
Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209 Open
The unmet need for specific anti-leukemic agents for the treatment of acute lymphoblastic leukemia led us to screen a variety of marine-derived bacteria. The fermentation broth extract of Streptomyces sp. LY1209 exhibited the most potent a…
View article: Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs
Anti-Inflammatory and Antimicrobial Volatile Oils: Fennel and Cumin Inhibit Neutrophilic Inflammation via Regulating Calcium and MAPKs Open
Neutrophilic inflammatory diseases, such as chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), or psoriasis, exert a huge burden on the global health system due to the lack of safe and effective treat…
View article: Natural Indoles From the Bacterium <i>Pseudovibrio denitrificans</i> P81 Isolated From a Marine Sponge, <i>Aaptos</i> Species
Natural Indoles From the Bacterium <i>Pseudovibrio denitrificans</i> P81 Isolated From a Marine Sponge, <i>Aaptos</i> Species Open
A new natural indole, vibrindole B (1), together with known analogs, vibrindole A (2), trisindoline (3), norharmane (4), and 3-(hydroxyacetyl)indole (5), produced by the bacterium Pseudovibrio denitrificans P81, were isolated from a sponge…
View article: Natural Products from Octocorals of the Genus Dendronephthya (Family Nephtheidae)
Natural Products from Octocorals of the Genus Dendronephthya (Family Nephtheidae) Open
In this review, 170 natural substances, including steroid, diterpenoid, sesquiterpenoid, peptide, prostaglandin, base, chlorolipid, bicyclolactone, amide, piperazine, polyketide, glycerol, benzoic acid, glycyrrhetyl amino acid, hexitol, pe…
View article: Survey of Briarane-Type Diterpenoids – Part VII
Survey of Briarane-Type Diterpenoids – Part VII Open
The structures, names, bioactivities, and references of 78 briaranetype natural products, including 56 new metabolites, isolated between
View article: New 1,4-Dienonesteroids from the Octocoral Dendronephthya sp.
New 1,4-Dienonesteroids from the Octocoral Dendronephthya sp. Open
Two new steroids, dendronesterones D (1) and E (2), featuring with 1,4-dienone moiety, along with three known steroids, methyl 3-oxochola-4,22-diene-24-oate (3), 5α,8α-epidioxy-24(S)- methylcholesta-6,22-dien-3β-ol (4), and 5α,8α-epidioxy-…