Young Joon Hong
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View article: Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction
Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction Open
In patients with AMI-rEF, beta-blockers were not independently associated with significantly reduced all-cause death after adjustment, though a trend was observed. Notably, beta-blocker use increased the risk of nonfatal myocardial infarct…
View article: Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease
Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease Open
Background Fractional flow reserve (FFR)‐guided or angiography‐guided complete revascularization has not been evaluated in patients with acute myocardial infarction (AMI) with multivessel disease and reduced left ventricular ejection fract…
View article: Evaluating the Efficacy of AI-Assisted Quantitative Coronary Angiography in Reducing Procedural Time for Primary PCI in STEMI Patients: A Retrospective Analysis
Evaluating the Efficacy of AI-Assisted Quantitative Coronary Angiography in Reducing Procedural Time for Primary PCI in STEMI Patients: A Retrospective Analysis Open
View article: [Investigating the correlation between white matter injury and cerebral perfusion in preterm infants using arterial spin labeling].
[Investigating the correlation between white matter injury and cerebral perfusion in preterm infants using arterial spin labeling]. Open
WMI in preterm infants correlates with localized cerebral hypoperfusion. ASL-detected perfusion abnormalities may provide novel insights into WMI pathogenesis.
View article: Novel artificial intelligence model using electrocardiogram for detecting acute myocardial infarction needing revascularization
Novel artificial intelligence model using electrocardiogram for detecting acute myocardial infarction needing revascularization Open
Aims Rapid myocardial revascularization in patients with acute myocardial infarction (AMI) is essential to improve clinical outcomes. There is still room for improvement in the timely diagnosis of AMI. This study aimed to develop an artifi…
View article: Comparison of rosuvastatin 10 mg plus ezetimibe versus rosuvastatin 20 mg in atherosclerotic cardiovascular disease and type 2 diabetes
Comparison of rosuvastatin 10 mg plus ezetimibe versus rosuvastatin 20 mg in atherosclerotic cardiovascular disease and type 2 diabetes Open
Studies comparing efficacy and safety of moderate-intensity statin plus ezetimibe versus high-intensity statin in patients with atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes (T2DM) are scarce. In this multicenter non-i…
View article: Impact of renal function on treatment strategies and clinical outcomes in acute myocardial infarction patients with multivessel disease
Impact of renal function on treatment strategies and clinical outcomes in acute myocardial infarction patients with multivessel disease Open
CR improved outcomes in patients with eGFR ≥60, whereas no difference was observed between CR and IR in those with eGFR <60. Therefore, IR may be a viable option for patients with reduced renal function.
View article: A Multi-Center, Prospective, Observational Study to Evaluate the Therapeutic Effectiveness and Safety of an Olmesartan/Amlodipine Plus Rosuvastatin Combination Treatment in Patients with Concomitant Hypertension and Dyslipidemia
A Multi-Center, Prospective, Observational Study to Evaluate the Therapeutic Effectiveness and Safety of an Olmesartan/Amlodipine Plus Rosuvastatin Combination Treatment in Patients with Concomitant Hypertension and Dyslipidemia Open
Introduction: This study assessed the therapeutic effectiveness of a single-pill combination (SPC) of olmesartan/amlodipine plus rosuvastatin for blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) in patients with hyperten…
View article: Three-Year Outcomes of a Bioabsorbable-Polymer Sirolimus-Eluting Stent in Patients With Acute Coronary Syndrome in Korea
Three-Year Outcomes of a Bioabsorbable-Polymer Sirolimus-Eluting Stent in Patients With Acute Coronary Syndrome in Korea Open
View article: Comparison of Thick Biolimus A9-Eluting Stent and Thin Zotarolimus-Eluting Stent in Multi-Vessel Percutaneous Coronary Intervention
Comparison of Thick Biolimus A9-Eluting Stent and Thin Zotarolimus-Eluting Stent in Multi-Vessel Percutaneous Coronary Intervention Open
ClinicalTrials.gov Identifier: NCT01947439.
View article: Clopidogrel Versus Aspirin Monotherapy in High-Risk Patients after Percutaneous Coronary Intervention (SMART-CHOICE 3): A Randomised, Open-Label, Multicentre Trial
Clopidogrel Versus Aspirin Monotherapy in High-Risk Patients after Percutaneous Coronary Intervention (SMART-CHOICE 3): A Randomised, Open-Label, Multicentre Trial Open
View article: Effectiveness of a Zotarolimus-Eluting Stent (Resolute Onyx<sup>TM</sup>) in Patients With Diffuse Long Coronary Artery Disease: Intravascular Ultrasound-guided vs. Angiography-guided Percutaneous Coronary Intervention
Effectiveness of a Zotarolimus-Eluting Stent (Resolute Onyx<sup>TM</sup>) in Patients With Diffuse Long Coronary Artery Disease: Intravascular Ultrasound-guided vs. Angiography-guided Percutaneous Coronary Intervention Open
View article: Valve-in-Valve TAVR With Bioprosthetic Valve Fracture and Snaring Technique in Extreme Horizontal Aorta
Valve-in-Valve TAVR With Bioprosthetic Valve Fracture and Snaring Technique in Extreme Horizontal Aorta Open
View article: Management of Abrupt Vessel Closure During Percutaneous Coronary Intervention: A Narrative Review
Management of Abrupt Vessel Closure During Percutaneous Coronary Intervention: A Narrative Review Open
View article: Non-culprit Lesion Location and FFR-guided Revascularization in Acute Myocardial Infarction With Multivessel Disease: FRAME-AMI Substudy
Non-culprit Lesion Location and FFR-guided Revascularization in Acute Myocardial Infarction With Multivessel Disease: FRAME-AMI Substudy Open
The NCL location did not affect the favorable outcomes of FFR-guided PCI over angiography-guided PCI in patients with AMI and MVD.
View article: Strategies of Revascularization and Mechanical Circulatory Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock: A Systematic Review With Updated Evidence
Strategies of Revascularization and Mechanical Circulatory Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock: A Systematic Review With Updated Evidence Open
View article: Differential statin intensity and outcomes in patients following myocardial infarction with very low low-density lipoprotein cholesterol
Differential statin intensity and outcomes in patients following myocardial infarction with very low low-density lipoprotein cholesterol Open
Statin intensity appeared to have no significant impact on clinical outcomes in AMI patients with LDL-C levels < 55 mg/dL. These results underscore the need for further investigations aimed at refining treatment strategies for this specifi…
View article: Impact of Total Coronary Occlusion on Long-term Outcomes in Patients with ST-segment Elevation Myocardial Infarction
Impact of Total Coronary Occlusion on Long-term Outcomes in Patients with ST-segment Elevation Myocardial Infarction Open
Purpose: This study aimed to investigate the impact of preprocedural total coronary occlusion on long-term cardiovascular outcomes in patients with ST-segment elevation myocardial infarction (STEMI) in the contemporary percutaneous coronar…
View article: YAK577 Attenuates Cardiac Remodeling and Fibrosis in Isoproterenol-Infused Heart Failure Mice by Downregulating MMP12
YAK577 Attenuates Cardiac Remodeling and Fibrosis in Isoproterenol-Infused Heart Failure Mice by Downregulating MMP12 Open
YAK577 acts as a novel heart failure drug through the HDAC8/MMP12 pathway.
View article: The Effects of Nicotine on Re-endothelialization, Inflammation, and Neoatherosclerosis After Drug-Eluting Stent Implantation in a Porcine Model
The Effects of Nicotine on Re-endothelialization, Inflammation, and Neoatherosclerosis After Drug-Eluting Stent Implantation in a Porcine Model Open
Nicotine inhibited re-endothelialization and promoted inflammation and NIH after PCI with DES in a porcine model.
View article: Ten-year trends in lipid management among patients after myocardial infarction in South Korea
Ten-year trends in lipid management among patients after myocardial infarction in South Korea Open
Background Dyslipidemia is an important risk factor for acute myocardial infarction. However, real-world data on its prevalence and lipid management trends for Korean patients with acute myocardial infarction are limited. This study aimed …
View article: Comparison of Clinical Outcomes between Drug-Eluting Balloons and Drug-Eluting Stents in Patients with Small Coronary Artery Disease
Comparison of Clinical Outcomes between Drug-Eluting Balloons and Drug-Eluting Stents in Patients with Small Coronary Artery Disease Open
Background/Aims: Drug-eluting balloons (DEBs) represent a novel therapeutic approach for patients with small coronary artery disease. However, further studies are needed to compare the clinical efficacy of DEBs versus drug-eluting stents (…
View article: Long‐Term Risk of Cardiovascular Death in Patients With Mildly Reduced Ejection Fraction After Acute Myocardial Infarction: A Multicenter, Prospective Registry Study
Long‐Term Risk of Cardiovascular Death in Patients With Mildly Reduced Ejection Fraction After Acute Myocardial Infarction: A Multicenter, Prospective Registry Study Open
Background The prognostic implication of mildly reduced ejection fraction (mrEF) after acute myocardial infarction has not been clearly demonstrated. We investigated the long‐term risk of cardiovascular death and its predictors in patients…
View article: Optimal timing of revascularization for patients with non-ST segment elevation myocardial infarction and severe left ventricular dysfunction
Optimal timing of revascularization for patients with non-ST segment elevation myocardial infarction and severe left ventricular dysfunction Open
Optimal timing of revascularization for patients who presented with non-ST segment elevation myocardial infarction (NSTEMI) and severe left ventricular (LV) dysfunction is unclear. A total of 386 NSTEMI patients with severe LV dysfunction …
View article: Widespread Use of Imaging-Guided PCI in Asia
Widespread Use of Imaging-Guided PCI in Asia Open
In recent years, a wealth of clinical data has emerged regarding intravascular imaging involving either intravascular ultrasound or optical coherence tomography. This surge in data has propelled the adoption of intravascular imaging-guided…
View article: Clinical Impact of Self-Recognition of Recurrent Acute Myocardial Infarction: From KRMI-RCC
Clinical Impact of Self-Recognition of Recurrent Acute Myocardial Infarction: From KRMI-RCC Open
Background/Objectives: Self-recognition of recurrent myocardial infarction (re-MI) may be essential for reducing prehospital time contrast to awareness of re-MI symptoms. However, data on the current status and clinical impact of self-reco…
View article: Drug-Coated Balloon Angioplasty in Patients Undergoing Complex Percutaneous Coronary Intervention
Drug-Coated Balloon Angioplasty in Patients Undergoing Complex Percutaneous Coronary Intervention Open
DCB-based PCI showed comparable risks of TVF vs those of DES-only PCI in patients with complex coronary artery lesions. DCB might be considered as a suitable alternative device to DES in patients undergoing complex PCI. (Long-term Outcomes…
View article: Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model
Efficacy and Safety Evaluation of Tacrolimus-Eluting Stent in a Porcine Coronary Artery Model Open
View article: Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial
Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial Open
gov. Unique identifier: NCT04626882; and URL: https://cris.nih.go.kr. Unique identifier: KCT0004457.
View article: Prognostic Implications of N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Non-ST-Elevation Myocardial Infarction
Prognostic Implications of N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Non-ST-Elevation Myocardial Infarction Open
In patients with NSTEMI who underwent PCI, an initial elevated NT-proBNP concentration was associated with higher risk of MACE at 3 years, driven primarily by higher risks of cardiac death or admission for heart failure. These results sugg…