Young Nyun Park
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View article: Deep Learning-Based Automatic Muscle Segmentation of the Thigh Using Lower Extremity CT Images
Deep Learning-Based Automatic Muscle Segmentation of the Thigh Using Lower Extremity CT Images Open
Background/Objectives: Sarcopenia and muscle composition have emerged as significant indicators in the fields of musculoskeletal and metabolic research. The objective of this study was to develop and validate a fully automated, deep learni…
View article: 153 Intestinal Cooling Prevents Sepsis Without Coagulopathy During REBOA Management of Hemorrhage
153 Intestinal Cooling Prevents Sepsis Without Coagulopathy During REBOA Management of Hemorrhage Open
View article: Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice
Macrophage transfer promotes intestinal mucosal healing by encouraging transit-amplifying cell expansion in mice Open
Cellular therapy, including stem cell injections, has been proved to be therapeutic for patients with inflammatory bowel disease (IBDs), showing promising outcomes of disease progression. However, challenges of stem cell therapy remain, su…
View article: LB1262 Sustained epithelial alarmin contribute to persistent hyperpigmentation after psoriasis remission by biologics
LB1262 Sustained epithelial alarmin contribute to persistent hyperpigmentation after psoriasis remission by biologics Open
View article: Biliary Adenofibroma Presenting as a Hyperenhancing Solid-Cystic Liver Mass: A Case Report
Biliary Adenofibroma Presenting as a Hyperenhancing Solid-Cystic Liver Mass: A Case Report Open
Biliary adenofibroma (BAF) is an extremely rare tumor, with fewer than 30 reported cases since it was first described in 1993. It is classified as a benign biliary neoplasm according to the 2019 World Health Organization tumor classificati…
View article: Synergistic anticancer effects of regorafenib and ginsenoside Rh3 in hepatocellular carcinoma through inhibition of the STAT3 signaling pathway
Synergistic anticancer effects of regorafenib and ginsenoside Rh3 in hepatocellular carcinoma through inhibition of the STAT3 signaling pathway Open
View article: OP0329 PREDICTING THE PROGRESSION OF INTERSTITIAL LUNG DISEASE IN RHEUMATOID ARTHRITIS: A MODEL DEVELOPED FROM CLINICAL AND SEROLOGIC FACTORS IN THE KORAIL COHORT
OP0329 PREDICTING THE PROGRESSION OF INTERSTITIAL LUNG DISEASE IN RHEUMATOID ARTHRITIS: A MODEL DEVELOPED FROM CLINICAL AND SEROLOGIC FACTORS IN THE KORAIL COHORT Open
View article: Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways
Cannabidiol potentiates p53-driven autophagic cell death in non-small cell lung cancer following DNA damage: a novel synergistic approach beyond canonical pathways Open
The search for more effective and safer cancer therapies has led to an increasing interest in combination treatments that use well-established agents. Here we explore the potential of cannabidiol (CBD), a compound derived from cannabis, to…
View article: Erratum to ‘Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial’ [Clin Mol Hepatol 2024;30:807-823]
Erratum to ‘Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial’ [Clin Mol Hepatol 2024;30:807-823] Open
View article: Ginsenoside Rh3 enhances regorafenib efficacy in hepatocellular carcinoma by modulating FGFR4-STAT3-YAP signaling pathway
Ginsenoside Rh3 enhances regorafenib efficacy in hepatocellular carcinoma by modulating FGFR4-STAT3-YAP signaling pathway Open
View article: Making Sense of ‘Porto‐Sinusoidal Vascular Disorder’: What Does It Mean for the Pathologist and the Patient?
Making Sense of ‘Porto‐Sinusoidal Vascular Disorder’: What Does It Mean for the Pathologist and the Patient? Open
View article: NADPH oxidase 4-SH3 domain-containing YSC84-like 1 complex participates liver inflammation and fibrosis
NADPH oxidase 4-SH3 domain-containing YSC84-like 1 complex participates liver inflammation and fibrosis Open
There is growing evidence that NADPH oxidase 4 (Nox4) in hepatocytes contributes to liver inflammation and fibrosis during the development of metabolic dysfunction-associated steatohepatitis (MASH). However, how Nox4 is regulated and leads…
View article: Clinical Results of Os Subfibulare Resection with Ligament Repair in Chronic Lateral Ankle Instability
Clinical Results of Os Subfibulare Resection with Ligament Repair in Chronic Lateral Ankle Instability Open
Category: Sports; Ankle Introduction/Purpose: Previous studies still have conflicting views on the size of the ossicle during ligament repair after ossicle removal. However, there is no standard for measuring the size of the ossicle. Furth…
View article: Transcriptomic profiling of intermediate cell carcinoma of the liver
Transcriptomic profiling of intermediate cell carcinoma of the liver Open
Background: Intermediate cell carcinoma (Int-CA) is a rare and enigmatic primary liver cancer characterized by uniform tumor cells exhibiting mixed features of both HCC and intrahepatic cholangiocarcinoma. Despite the unique pathological f…
View article: Sarcomatoid change in combined hepatocellular carcinoma and cholangiocarcinoma as a poor prognostic factor
Sarcomatoid change in combined hepatocellular carcinoma and cholangiocarcinoma as a poor prognostic factor Open
Sarcomatoid change is a poor prognostic factor for resected cHCC-CC.
View article: Severe acute liver disease in adults: Contemporary role of histopathology
Severe acute liver disease in adults: Contemporary role of histopathology Open
Liver biopsies have consistently contributed to our understanding of the pathogenesis and aetiologies of acute liver disease. As other diagnostic modalities have been developed and refined, the role of biopsy in the management of patients …
View article: Macroscopic Characterization of Hepatocellular Carcinoma: An Underexploited Source of Prognostic Factors
Macroscopic Characterization of Hepatocellular Carcinoma: An Underexploited Source of Prognostic Factors Open
The macroscopic appearance of a tumor such as hepatocellular carcinoma (HCC) may be defined as its phenotype which is de facto dictated by its genotype. Therefore, macroscopic characteristics of HCC are unlikely random but rather re…
View article: Predictive modeling provides insight into the clinical heterogeneity associated with<i>TARS1</i>loss-of-function mutations
Predictive modeling provides insight into the clinical heterogeneity associated with<i>TARS1</i>loss-of-function mutations Open
Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed, essential enzymes that complete the first step of protein translation: ligation of amino acids to cognate tRNAs. Genes encoding ARSs have been implicated in myriad dominant and …
View article: Biallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder
Biallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder Open
View article: Prognostic Significance of the Macrotrabecular-Massive Hepatocellular Carcinoma Subtype in Liver Transplantation: A Retrospective Cohort Study
Prognostic Significance of the Macrotrabecular-Massive Hepatocellular Carcinoma Subtype in Liver Transplantation: A Retrospective Cohort Study Open
View article: <scp>ERS</scp>: A simple scoring system to predict early recurrence after surgical resection for hepatocellular carcinoma
<span>ERS</span>: A simple scoring system to predict early recurrence after surgical resection for hepatocellular carcinoma Open
Background Surgical resection (SR) is a potentially curative treatment of hepatocellular carcinoma (HCC) hampered by high rates of recurrence. New drugs are tested in the adjuvant setting, but standardised risk stratification tools of HCC …
View article: Steatotic hepatocellular carcinoma: Association of <scp>MRI</scp> findings to underlying liver disease and clinicopathological characteristics
Steatotic hepatocellular carcinoma: Association of <span>MRI</span> findings to underlying liver disease and clinicopathological characteristics Open
Background & Aims Fatty change is commonly observed in hepatocellular carcinoma (HCC); however, the characteristics of steatotic and steatohepatitic HCCs are not well understood. Methods This retrospective study included patients with HCCs…
View article: Supplementary Table 5 from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Supplementary Table 5 from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma Open
Coverage Statistics and List of Genes for Targeted Sequencing.
View article: Supplementary Methods and Supplementary Figure and Table Legends from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Supplementary Methods and Supplementary Figure and Table Legends from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma Open
Further details of methods, in addition to the supplementary figure and table legends.
View article: Supplementary Figure 2 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma
Supplementary Figure 2 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma Open
PDF file - 2527K, Relationship between RASSF1A, YAP, and AREG histoscores.
View article: Supplementary Figure 1 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma
Supplementary Figure 1 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma Open
PDF file - 1379K, Immunohistochemical analysis of nuclear and cytoplasmic YAP protein localization in human multistep hepatocarcinogenesis.
View article: Data from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Data from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma Open
Cholangiocarcinoma (CCA) is a hepatobiliary malignancy exhibiting high incidence in countries with endemic liver-fluke infection. We analyzed 489 CCAs from 10 countries, combining whole-genome (71 cases), targeted/exome, copy-number, gene …
View article: Supplementary Methods and Supplementary Figure and Table Legends from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Supplementary Methods and Supplementary Figure and Table Legends from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma Open
Further details of methods, in addition to the supplementary figure and table legends.
View article: Supplementary Figures 1-6 from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma
Supplementary Figures 1-6 from Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma Open
Supplementary Figure 1. Unsupervised Clustering on CCA samples. Supplementary Figure 2. Alterations Found in CCA Clusters. Supplementary Figure 3. MAP2K4 Homozygous Deletions and ERBB2 Amplifications. Supplementary Figure 4. Alterations Re…
View article: Supplementary Figure 2 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma
Supplementary Figure 2 from RASSF1A-Mediated Regulation of AREG via the Hippo Pathway in Hepatocellular Carcinoma Open
PDF file - 2527K, Relationship between RASSF1A, YAP, and AREG histoscores.