Youngheun Cho
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View article: Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance
Development of Polymersomes Co-Delivering Doxorubicin and Melittin to Overcome Multidrug Resistance Open
Multidrug resistance (MDR) is one of the major barriers in chemotherapy. It is often related to the overexpression of efflux receptors such as P-glycoprotein (P-gp). Overexpressed efflux receptors inhibit chemotherapeutic efficacy by pumpi…
View article: Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos
Phospholipid-based nanodrill technology for enhanced intracellular delivery of nano-sized cargos Open
Nanosized drug delivery systems typically enter the cell via endocytosis. However, a significant amount of the endocytosed cargo cannot effectively escape from the endosome, resulting in drug degradation. Therefore, there are several ongoi…