Young‐Min Chung
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View article: Missing data in single-cell transcriptomes reveals transcriptional shifts
Missing data in single-cell transcriptomes reveals transcriptional shifts Open
Profiling thousands of single cell transcriptomes is routine, yet cell prioritization based on response to biological perturbations is challenging and confounded by clustering, normalization and dimensionality reduction strategies. We deve…
View article: Catalytic Wet Peroxide Oxidation of Methyl Orange Over Bifunctional Pd/Fe-Mof Catalysts with In-Situ Generated H2o2
Catalytic Wet Peroxide Oxidation of Methyl Orange Over Bifunctional Pd/Fe-Mof Catalysts with In-Situ Generated H2o2 Open
View article: Ethylene Oligomerization Over Mesoporous Feni-Btc Catalysts: Effect of the Textural Properties of the Catalyst on the Reaction Performance
Ethylene Oligomerization Over Mesoporous Feni-Btc Catalysts: Effect of the Textural Properties of the Catalyst on the Reaction Performance Open
View article: Catalytic Wet Peroxide Oxidation of Organic Dye with In-Situ Generated H2o2 Over Bifunctional Fe-Pt@Pd/Sio2 Catalyst Prepared by Double-Metal Complex Salt Approach
Catalytic Wet Peroxide Oxidation of Organic Dye with In-Situ Generated H2o2 Over Bifunctional Fe-Pt@Pd/Sio2 Catalyst Prepared by Double-Metal Complex Salt Approach Open
View article: Catalytic Wet Peroxide Oxidation with In-Situ Generated H2o2: An Efficient Strategy for Improving the Stability of Metal-Organic Framework Catalysts
Catalytic Wet Peroxide Oxidation with In-Situ Generated H2o2: An Efficient Strategy for Improving the Stability of Metal-Organic Framework Catalysts Open
View article: FOXO3-dependent suppression of PD-L1 promotes anticancer immune responses via activation of natural killer cells.
FOXO3-dependent suppression of PD-L1 promotes anticancer immune responses via activation of natural killer cells. Open
Boosting anticancer immunity by blocking immune checkpoints such as the programmed death-1 (PD-1) or its ligand (PD-L1) is a breakthrough anticancer therapy. However, many cancer patients do not respond well to immune checkpoint blockades …
View article: Sensitizing tumors to anti-PD-1 therapy by promoting NK and CD8+ T cells via pharmacological activation of FOXO3
Sensitizing tumors to anti-PD-1 therapy by promoting NK and CD8+ T cells via pharmacological activation of FOXO3 Open
Background Stimulating antitumor immunity by blocking programmed death-1 (PD-1) or its ligand (programmed death-ligand 1 (PD-L1) is a promising antitumor therapy. However, numerous patients respond poorly to PD-1/PD-L1 blockade. Unresponsi…
View article: Minimizing energy demand and environmental impact for sustainable NH3 and H2O2 production—A perspective on contributions from thermal, electro-, and photo-catalysis
Minimizing energy demand and environmental impact for sustainable NH3 and H2O2 production—A perspective on contributions from thermal, electro-, and photo-catalysis Open
There is an urgent need to provide adequate and sustainable supplies of water and food to satisfy the demand of an increasing population. Catalysis plays important roles in meeting these needs by facilitating the synthesis of hydrogen pero…
View article: Ursolic acid supplementation decreases markers of skeletal muscle damage during resistance training in resistance-trained men: a pilot study
Ursolic acid supplementation decreases markers of skeletal muscle damage during resistance training in resistance-trained men: a pilot study Open
Ursolic acid (UA) supplementation was previously shown to improve skeletal muscle function in resistance-trained men. This study aimed to determine, using the same experimental paradigm, whether UA also has beneficial effects on exercise-i…
View article: Pharmacological activation of FOXO3 suppresses triple-negative breast cancer <i>in vitro</i> and <i>in vivo</i>
Pharmacological activation of FOXO3 suppresses triple-negative breast cancer <i>in vitro</i> and <i>in vivo</i> Open
Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. Lacking effective therapeutic options hinders treatment of TNBC. Here, we show that bepridil (BPD) and trifluoperazine (TFP), which are FDA-approved drugs for t…
View article: Effects of Low-Dose Bisphenol A on DNA Damage and Proliferation of Breast Cells: The Role of c-Myc
Effects of Low-Dose Bisphenol A on DNA Damage and Proliferation of Breast Cells: The Role of c-Myc Open
Low-dose BPA exerted c-Myc-dependent genotoxic and mitogenic effects on ERα-negative mammary cells. These findings provide significant evidence of adverse effects of low-dose BPA on mammary cells.
View article: A Method for Suppression of Active Metal Leaching during the Direct Synthesis of H<sub>2</sub>O<sub>2</sub>by Using Polyelectrolyte Multilayers
A Method for Suppression of Active Metal Leaching during the Direct Synthesis of H<sub>2</sub>O<sub>2</sub>by Using Polyelectrolyte Multilayers Open
본 연구에서는 일반적인 귀금속 담지법과 담체 위에 형성한 고분자 전해질 다층 박막 내에 귀금속을 내포시키는 방법으로 촉매를 제조하고, 과산화수소 직접제조 반응에 적용하여 촉매의 제조 방법이 과산화수소 생산성 및 촉매 수명에 미치는 영향을 조사하였다. 촉매의 활성은 제조 방법에 상관없이 담체의 산세기에 크게 의존하였으며, 사용한 담체들 중 산세기가 가장 강한 HBEA(SAR=25)를 사용한 경우가 활성이 가장 우수하였다. 단순…
View article: The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro
The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro Open