Yu Ah Hong
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View article: Carbamazepine-induced pure red cell aplasia in an elderly patient with ESKD on hemodialysis: a case report
Carbamazepine-induced pure red cell aplasia in an elderly patient with ESKD on hemodialysis: a case report Open
View article: Abdominal computed tomography–assessed muscle quality and its prognostic value in patients with advanced chronic kidney disease initiating hemodialysis
Abdominal computed tomography–assessed muscle quality and its prognostic value in patients with advanced chronic kidney disease initiating hemodialysis Open
Background Skeletal muscle density (SMD), assessed via L3 level computed tomography (CT), is a critical marker of muscle quality with remarkable prognostic value in various clinical settings. This study investigates prognostic values of th…
View article: Clinical challenges and individualized approaches to dialysis therapy in older adults
Clinical challenges and individualized approaches to dialysis therapy in older adults Open
Global population aging has substantially increased in the number of older adults who undergo kidney replacement therapy (KRT). Age-related physiological changes and functional dependence in this population lead to the multifaceted clinica…
View article: Effects of hospitalization before hemodialysis on mortality in dialysis patients
Effects of hospitalization before hemodialysis on mortality in dialysis patients Open
View article: MNQ derivative D19 alleviates LPS-induced inflammation and oxidative stress in sheep follicular granulosa cells through the GPX4-mediated ferroptosis
MNQ derivative D19 alleviates LPS-induced inflammation and oxidative stress in sheep follicular granulosa cells through the GPX4-mediated ferroptosis Open
Introduction 2-methoxy-1,4-naphthoquinone (MNQ), a compound derived from Impatiens balsamina L ., is recognized for its anti-inflammatory and antioxidant properties. However, the effects of D19, a derivative of MNQ, remain unexplored. This…
View article: Associated factors of osteoporosis and the impact of osteoporosis on all-cause mortality in incident hemodialysis older patients
Associated factors of osteoporosis and the impact of osteoporosis on all-cause mortality in incident hemodialysis older patients Open
We should consider the importance of bone health in patients undergoing incident hemodialysis and pay attention to the use of phosphate binders and fracture prevention.
View article: The organelle-tethering protein PDZD8 regulates endolysosomal maturation and TLR9-NF-κB signaling in cisplatin-induced acute kidney injury
The organelle-tethering protein PDZD8 regulates endolysosomal maturation and TLR9-NF-κB signaling in cisplatin-induced acute kidney injury Open
This study reveals the critical role of PDZD8 in maintaining endolysosomal homeostasis and regulating the TLR9-NF-κB inflammatory pathway in cisplatin-induced acute kidney injury (AKI). Loss of PDZD8 impaired endolysosomal function, suppre…
View article: Strengthening monocarboxylate transporters by adiponectin receptor agonist ameliorates diabetic peripheral neuropathy
Strengthening monocarboxylate transporters by adiponectin receptor agonist ameliorates diabetic peripheral neuropathy Open
BACKGROUND: Disruption of energy support to peripheral nerves leads to dysfunction and degeneration of both neuronal axons and Schwann cells (SCs). METHODS: We evaluated the effects of the adiponectin receptor (AdipoR) agonist, AdipoRon on…
View article: Prediction model for 6-month mortality in incident older hemodialysis patients in South Korea
Prediction model for 6-month mortality in incident older hemodialysis patients in South Korea Open
Background: Early mortality following hemodialysis initiation hinders survival improvement in older patients. This study aimed to develop a clinical risk model for predicting 6-month mortality after dialysis initiation in older Korean hemo…
View article: Association Between Alcohol Consumption and the Risk of Incident Chronic Kidney Disease: A Korean Nationwide Study of Community-Dwelling Older Adults
Association Between Alcohol Consumption and the Risk of Incident Chronic Kidney Disease: A Korean Nationwide Study of Community-Dwelling Older Adults Open
Background/Objectives: This study examined the effects of alcohol consumption on chronic kidney disease (CKD) risk in community-dwelling older adults. Methods: A nationwide retrospective observational study was conducted using NHIS-Senior …
View article: The impact of body mass index on mortality according to age in hemodialysis patients: an analysis of the Korean Renal Data System
The impact of body mass index on mortality according to age in hemodialysis patients: an analysis of the Korean Renal Data System Open
The impact of age on the relationship between body mass index (BMI) and all-cause mortality in hemodialysis (HD) patients is not clearly understood. Using data from the Korean Renal Data System (2001–2022), we analyzed 66,129 HD patients, …
View article: Impact of Heart Function on Elderly Incident Hemodialysis Patients
Impact of Heart Function on Elderly Incident Hemodialysis Patients Open
View article: Skeletal Muscle Measurements Based on Abdominal Computerized Tomography (CT) Predict Risk of Osteoporosis in Incident Hemodialysis Patients
Skeletal Muscle Measurements Based on Abdominal Computerized Tomography (CT) Predict Risk of Osteoporosis in Incident Hemodialysis Patients Open
Objective: Osteoporosis is prevalent in patients with chronic kidney disease (CKD), with risk increasing as CKD progresses, subsequently elevating fracture risk. While previous studies have shown a link between low skeletal muscle mass and…
View article: Organelle communication maintains mitochondrial and endosomal homeostasis during podocyte lipotoxicity
Organelle communication maintains mitochondrial and endosomal homeostasis during podocyte lipotoxicity Open
Organelle stress exacerbates podocyte injury, contributing to perturbed lipid metabolism. Simultaneous organelle stresses can occur in the kidney in the diseased state; therefore, a thorough analysis of organelle communication is crucial f…
View article: Mortality in patients receiving renal replacement therapy in South Korea
Mortality in patients receiving renal replacement therapy in South Korea Open
While annual mortality and survival probability after dialysis initiation have generally improved in dialysis patients, there has been a temporary deterioration during the COVID-19 pandemic, most pronounced in the elderly.
View article: The association between physical fitness and mental health among college students: a cross-sectional study
The association between physical fitness and mental health among college students: a cross-sectional study Open
Introduction Physical inactivity and mental health disorders are emerging threats to public health in China. Previous research on links between exercise and mental wellbeing have focused on clinical populations, with little evidence from t…
View article: Trends in clinical outcomes of older hemodialysis patients: data from the 2023 Korean Renal Data System (KORDS)
Trends in clinical outcomes of older hemodialysis patients: data from the 2023 Korean Renal Data System (KORDS) Open
With an increasing aging population, the mean age of patients with end-stage kidney disease (ESKD) is globally increasing. However, the current clinical status of elderly patients undergoing hemodialysis (HD) is rarely reported in Korea. T…
View article: Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway
Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway Open
View article: #1522 Comparative analysis of clinical and pathological traits in IgA nephropathy with nephrotic range proteinuria based on serum albumin level
#1522 Comparative analysis of clinical and pathological traits in IgA nephropathy with nephrotic range proteinuria based on serum albumin level Open
Background and Aims Presently, the clinical outcomes associated with IgA nephropathy exhibiting heavy proteinuria and the potential correlation between decreasing serum albumin levels and adverse prognosis have not been conclusively establ…
View article: #939 Association between alcohol consumption and the risk of incident chronic kidney disease in community-dwelling older adults
#939 Association between alcohol consumption and the risk of incident chronic kidney disease in community-dwelling older adults Open
Background and Aims The relationship between alcohol consumption and kidney function decline is not well established, especially in older adults. This study aimed to investigate the effects of alcohol consumption on the risk of incident ch…
View article: Understanding the Korean Dialysis Cohort for Mineral, Vascular Calcification, and Fracture (ORCHESTRA) Study: Design, Method, and Baseline Characteristics
Understanding the Korean Dialysis Cohort for Mineral, Vascular Calcification, and Fracture (ORCHESTRA) Study: Design, Method, and Baseline Characteristics Open
Introduction: End-stage renal disease (ESRD) is a growing disease worldwide, including Korea. This is an important condition that affects patient outcome. To provide optimal management for mineral disturbance, vascular calcif…
View article: Author Correction: Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study
Author Correction: Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study Open
View article: Impact of obesity on renal function in elderly Korean adults: a national population-based cohort study
Impact of obesity on renal function in elderly Korean adults: a national population-based cohort study Open
In elderly Korean adults, metabolic syndrome and the number of its components were associated with a higher risk of renal function decline, but BMI or WC was not significant.
View article: Association between dementia diagnosis at dialysis initiation and mortality in older patients with end-stage kidney disease in South Korea
Association between dementia diagnosis at dialysis initiation and mortality in older patients with end-stage kidney disease in South Korea Open
Background: The prevalence of dementia is 2- to 7-fold higher among patients with end-stage kidney disease (ESKD) than among the general population; however, its clinical implications in this population remain unclear. Therefore, this stud…
View article: Status and trends in epidemiologic characteristics of diabetic end-stage renal disease: an analysis of the 2021 Korean Renal Data System
Status and trends in epidemiologic characteristics of diabetic end-stage renal disease: an analysis of the 2021 Korean Renal Data System Open
Korean Renal Data System (KORDS) is a nationwide end-stage renal disease (ESRD) registry database operated by the Korean Society of Nephrology (KSN). Diabetes mellitus is currently the leading cause of ESRD in Korea; this article provides …
View article: Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study
Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study Open
View article: Association between alcohol consumption and the risk of incident chronic kidney disease in community-dwelling older adults: a Korean nationwide population-based senior cohort study
Association between alcohol consumption and the risk of incident chronic kidney disease in community-dwelling older adults: a Korean nationwide population-based senior cohort study Open
Background The relationship between alcohol consumption and kidney function decline is not well established, especially in older adults. This study aimed to investigate the effects of alcohol consumption on the risk of incident chronic kid…
View article: Adiponectin Receptor Agonist Ameliorates Diabetic Peripheral Neuropathy by Strengthening Metabolic Modulation of Monocarboxylate Transporters
Adiponectin Receptor Agonist Ameliorates Diabetic Peripheral Neuropathy by Strengthening Metabolic Modulation of Monocarboxylate Transporters Open
View article: Clinical significance of neutrophil-to-lymphocyte ratio on the risk of abdominal aortic calcification and decreased bone mineral density in patients with end-stage kidney disease
Clinical significance of neutrophil-to-lymphocyte ratio on the risk of abdominal aortic calcification and decreased bone mineral density in patients with end-stage kidney disease Open
Inflammation plays a major role in the pathogenesis of chronic kidney disease (CKD), but the relationship between systemic inflammation and CKD-mineral bone disease is unclear. We aimed to investigate whether the neutrophil-to-lymphocyte r…
View article: Effect of low-density lipoprotein level and mortality in older incident statin-naïve hemodialysis patients
Effect of low-density lipoprotein level and mortality in older incident statin-naïve hemodialysis patients Open
Background This study aimed to analyze low-density lipoprotein cholesterol (LDL-C) levels and their relationship with mortality in order to identify the appropriate lipid profile for older Korean hemodialysis patients. Methods We enrolled …