Explanipedia

Effects of Diverting Stoma Creation in Minimally Invasive Surgery for Rectal Cancer Open

Hirotaka Momose, Makoto Takahashi, Masaya Kawai, Kiichi Sugimoto, H. Takahashi , et al. · 2025

DS creation is effective for avoiding reoperation for AL. Preoperative GPS ≥1 is a risk factor for AL in low anterior resection with a DS for rectal cancer. Thus, DS construction should be considered in a case with an elevated preoperative…

A pilot study on the safety and efficacy of neoadjuvant chemo‑adoptive immunotherapy for locally advanced rectal cancer Open

Yu Okazawa, Takashi Kamigaki, Kiichi Sugimoto, Takeshi Yamada, Yoichiro Yoshida , et al. · 2024

The safety and efficacy of combination therapy of immune cell therapy and chemotherapy [chemo-adoptive immunotherapy (CAIT)] for patients with stage IV or recurrent colorectal cancer have been reported. In the present study, the safety and…

Risk factors for anastomotic leakage in Low Anterior Resection with a Diverting stoma for rectal cancer: A case control study Open

Hirotaka Momose, Makoto Takahashi, Masaya Kawai, Kiichi Sugimoto, Kumpei Honjo , et al. · 2023

Background In rectal cancer surgery, a diverting stoma (DS) is used to reduce anastomotic leakage (AL). However, there is still uncertainty whether use of a DS really avoids AL. In this study, we identified risk factors for AL coexisting w…

Positive Circumferential Resection Margin in Rectal Cancer Is a Robust Predictor of Poor Long-term Prognosis With Clinicopathological Bias Between Groups Compensated by Propensity-score Matching Analysis Open

Kiichi Sugimoto, HIROMITSU TAKAHASHI, Yuki Yuki, Takahiro Irie, Megumi Kawaguchi , et al. · 2023

PS matching analysis demonstrated that RFS, LRFS, NLRFS, and CSS were significantly worse among patients in the CRM (+) group compared with those in the CRM (-) group. The present results indicate that CRM (+) is a robust predictor of long…

Local recurrence of submucosal invasive colorectal cancer after endoscopic submucosal dissection revealed by copy number variation Open

Yu Okazawa, Kiichi Sugimoto, Yuki Ii, Takahiro Irie, Megumi Kawaguchi , et al. · 2023

We report a case in which analysis of copy number variation revealed local recurrence of submucosal invasive colorectal cancer after curative endoscopic submucosal dissection (ESD). An 86‐year‐old man with a history of abdominoperineal res…

Richter’s Hernia with Reduction En Masse of Left Inguinal Hernia — A Case Report — Open

Kazumasa Kure, Ryoichi Tsukamoto, Yu Okazawa, Masaya Kawai, Koichiro Niwa , et al. · 2023

Surgical Treatment for Mucosal Prolapse after Intersphincteric Resection Open

Rina Takahashi, Makoto Takahashi, Yuki Ii, Megumi Kawaguchi, Hirotaka Momose , et al. · 2023

はじめに：括約筋間直腸切除術後（Intersphincteric resection：ISR）後の粘膜脱は，治療法として確立されたものはないが，当科ではDelorme手術を施行しており，その臨床経験を報告する．

Benefits and risks of diverting stoma creation during rectal cancer surgery Open

Masaya Kawai, Kazuhiro Sakamoto, Kumpei Honjo, Yu Okazawa, Rina Takahashi , et al. · 2022

Purpose: A consensus has been reached regarding diverting stoma (DS) construction in rectal cancer surgery to avoid reoperation related to anastomotic leakage. However, the incidence of stoma-related complications (SRCs) remains high. In t…

CHFR-Promoter-Methylation Status Is Predictive of Response to Irinotecan-based Systemic Chemotherapy in Advanced Colorectal Cancer Open

Toshiaki Hagiwara, Kiichi Sugimoto, Hirotaka Momose, Takahiro Irie, Kumpei Honjo , et al. · 2022

We investigated whether promoter methylation of the checkpoint-with-forkhead-and-ring-finger-domains (CHFR) gene is a predictor of the efficacy of irinotecan-based systemic chemotherapy for advanced colorectal cancer (CRC) patients.CHFR-pr…

Study of Purse-string Skin Closure Plus Negative-pressure Wound Therapy for Stoma Closure Open

Yu Okazawa, Yutaka Kojima, Kazuhiro Takehara, SHOUKO NOJIRI, Kota Amemiya , et al. · 2022

Our study suggests that PSC plus NPWT might be more effective for wound healing after stoma closure than only PSC.

Diverting Stoma Complications in Rectal Cancer Surgery. Open

Masaya Kawai, Kazuhiro Sakamoto, Kumpei Honjo, Yu Okazawa, Rina Takahashi , et al. · 2021

Background : A consensus regarding diverting stoma (DS) construction in rectal cancer surgery was reached to avoid reoperation related to anastomotic leakage. However, the incidence of stoma-related complications (SRCs) remains high. In th…

Case of Incarcerated Femoral Hernia Treated with Laparoscopic Surgery after Groin Hernia Repair Open

Yuki Tsuchiya, Hirotaka Momose, Kazumasa Kure, Hisashi Ro, Rina Takahashi , et al. · 2021

An 81-year-old man was brought to our hospital due to a suspicion of left incarcerated femoral hernia. He was previously diagnosed with incarcerated left groin hernia and was treated using the mesh plug method 1 month back at another hospi…

Usefulness of an IL-6 Semi-Quantification Kit in Patients with Perforative Peritonitis Open

Ryosuke Ichikawa, Kiichi Sugimoto, Kazumasa Kure, Kumpei Honjo, Rina Takahashi , et al. · 2021

Objective: As gastrointestinal tract perforation frequently causes severe sepsis, it is associated with a poor prognosis. We investigated the usefulness of measuring blood interleukin-6 (IL-6) levels using a simple semi-quantitative analys…

Laparoscopic Surgery and Robot-Assisted Surgery for Colorectal Cancer With Persistent Descending Mesocolon Open

Yutaka Kojima, Kazuhiro Sakamoto, Masaya Kawai, Yu Okazawa, Kazumasa Kure , et al. · 2020

Background: Persistent descending mesocolon (PDM) is a case of colonic replacement and adhesion as a result of abnormal fixation of the gastrointestinal tract. In laparoscopic surgery, it is performed when the patient is in an unconscious …

Simultaneous robot-assisted surgery for rectal cancer and prostatic lesions Open

Yutaka Kojima, Kazuhiro Sakamoto, Shigeo Horie, Yuichi Tomiki, Masaya Kawai , et al. · 2020

Robotic surgery has become prevalent in many departments all over the world because of its usefulness. It is used in many cases, as well as in gastrointestinal surgery, which treats the rectum as pelvic surgery, urology and gynecology. We …

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2020

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kinase levels postoperatively. In this study, we compared postoperative complications between patients undergoing robo…

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2020

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kina se levels postoperatively. In this study, we compared postoperative complications between patients undergoing rob…

A case of ileus surgery using the water pressure method against ileus caused by incarceration into the inverted bladder diverticulum Open

Hirotsugu Morioka, Jun Aoki, Kazuyoshi Fujino, Yuki Sugahara, Michihiro Orihata , et al. · 2020

Background Ileus is quite a common disease, but is associated with various causes. As far as we know, there have only been one case of ileus due to inverted bladder diverticulum, which is extremely rare. Case presentation The patient was a…

Two Cases of Two-stage Surgery Preceded by Endovascular Aneurysm Repair for Colorectal Cancer with Abdominal Aortic Aneurysm Open

Kosuke Mizukoshi, Hirotaka Momose, Yu Okazawa, Hisashi Ro, Masaya Kawai , et al. · 2020

腹部大動脈瘤を併存した大腸癌に対し，ステントグラフト内挿術を先行し，二期的手術を施行した2例を経験したので報告する．

Significance of Serum p53 Antibody as a Tumor Marker in Colorectal Cancer Open

Rina Takahashi, Kazuhiro Sakamoto, Kiichi Sugimoto, Shunsuke Motegi, Ryoichi Tsukamoto , et al. · 2019

Objective . We examined serum anti-p53 antibodies (S-p53Ab) in colorectal cancer. Specifically, we retrospectively investigated the use of S-p53Ab as a prognostic marker after surgery for colorectal cancer. Materials and Methods . The leve…

Creatine kinase elevation after robotic surgery for rectal cancer due to a prolonged lithotomy position Open

Yuki Tsuchiya, Shinya Munakata, Ryoichi Tsukamoto, Yu Okazawa, Kosuke Mizukoshi , et al. · 2019

Background Robotic surgery for rectal cancer, which is now performed worldwide, can be associated with elevated creatine kina se levels postoperatively. In this study, we compared postoperative complications between patient undergoing robo…

Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state Open

Kosuke Mizukoshi, Yu Okazawa, Hiroshi Haeno, Yu Koyama, Kaidiliayi Sulidan , et al. · 2019

Emerging evidence supports the theory that tumor cell clusters efficiently metastasize to distant organs. However, the roles of epithelial‐to‐mesenchymal transition (EMT) in metastasizing tumor cell clusters have not yet been fully elucida…

Effectiveness of Endoscopic Sclerotherapy with Aluminum Potassium Sulfate and Tannic Acid as a Non-Surgical Treatment for Internal Hemorrhoids Open

Yuichi Tomiki, Jun Aoki, Shunsuke Motegi, Rina Takahashi, Toshiaki Hagiwara , et al. · 2019

Endoscopic ALTA sclerotherapy is equivalent to standard ALTA therapy in terms of efficacy, adverse events, and recurrence. Therefore, it is a useful non-surgical option for patients with internal hemorrhoids who prefer a less invasive trea…

Colorectal Perforation in Patients with Connective Tissue Disease Open

Kiichi Sugimoto, Kazuhiro Sakamoto, Yu Okazawa, Rina Takahashi, Kosuke Mizukoshi , et al. · 2019

Purpose. The goal of this retrospective study was to identify prognostic factors associated with mortality after surgery for colorectal perforation among patients with connective tissue disease (CTD) and to review postoperative outcomes ba…

Study on the Efficacy of Daikenchuto on Bowel Motility after Laparoscopic Resection of Colorectal Cancer Open

Yutaka Kojima, Kazuhiro Sakamoto, Yuichi Tomiki, Kunihiko Nagakari, Atsushi Okuzawa , et al. · 2019

Laparoscopic right colectomy for a patient with situs inversus totalis Open

Yutaka Kojima, Kazuhiro Sakamoto, Yuichi Tomiki, Kiichi Sugimoto, Yu Okazawa , et al. · 2019

Situs inversus totalis (SIT) is rare congenital anomaly characterized by an inversion of the thoracic and abdominal viscera that crates a mirror image. Recently, several laparoscopic operations have been reported in patients with SIT. We h…

Surgery in a Case of Rectosigmoid Colon Cancer Associated with a Type II Endoleak as a Complication after Endovascular Aneurysm Repair (EVAR) for Abdominal Aortic Aneurysm (AAA) Open

Kiichi Sugimoto, Kazuhiro Sakamoto, Toshiaki Hagiwara, Yurika Makino, Yu Okazawa , et al. · 2019

Device used for Laparoscopic Management of Urachal Remnants at our Department Open

Yu Okazawa, Hirotsugu Morioka, Michitoshi Goto, Michihiro Orihata, Kazuhiro Sakamoto , et al. · 2019

目的:当科で5例の尿膜管遺残症患者に対して施行した腹腔鏡下尿膜管摘出術に関して報告する.

High-sensitivity Detection of Micrometastases Generated by GFP Lentivirus-transduced Organoids Cultured from a Patient-derived Colon Tumor Open

Yu Okazawa, Kosuke Mizukoshi, Yu Koyama, Shoki Okubo, Hiromitsu Komiyama , et al. · 2018

Despite current advances in human colorectal cancer (CRC) treatment, few radical therapies are effective for the late stages of CRC. To overcome this clinical challenge, tumor xenograft mouse models using long-established human carcinoma c…

Two Patients with Large Colonic Lipomas for which Endoscopic Unroofing was Ineffective Open

Yuichi Tomiki, Koichiro Niwa, Kiichi Nagayasu, Yu Okazawa, Shingo Ito , et al. · 2016

Endoscopic unroofing is effective for treating large colonic lipomas. However, additional endoscopic resection is occasionally required when the outcomes of initial unroofing are incomplete. The colonoscopy of an 82-year-old woman with abd…

Yu Okazawa YOU? Author Swipe