Yuehua Pu
YOU?
Author Swipe
View article: A one-pot, visual, multiplex microfluidic digital PCR chip for simultaneous point-of-care detection, genotyping, and macrolide resistance assessment of Mycoplasma pneumoniae
A one-pot, visual, multiplex microfluidic digital PCR chip for simultaneous point-of-care detection, genotyping, and macrolide resistance assessment of Mycoplasma pneumoniae Open
Mycoplasma pneumoniae (M. pneumoniae) is a leading cause of community-acquired pneumonia, especially concerning for young children. Effective management and infection control necessitate rapid, convenient, and user-friendly methods for ear…
View article: Predicting sarcopenia risk in stroke patients: a comprehensive nomogram incorporating demographic, anthropometric, and biochemical indicators
Predicting sarcopenia risk in stroke patients: a comprehensive nomogram incorporating demographic, anthropometric, and biochemical indicators Open
Objective Although there is a strong correlation between stroke and sarcopenia, there has been a lack of research into the potential risks associated with post-stroke sarcopenia. Predictors of sarcopenia are yet to be identified. We aimed …
View article: Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization
Deviation From Personalized Blood Pressure Targets Correlates With Worse Outcome After Successful Recanalization Open
Background Personalized blood pressure (BP) management for patients with acute ischemic stroke after successful endovascular thrombectomy lacks evidence. We aimed to investigate whether the deviation of BP from cerebral autoregulation limi…
View article: Deviation from Personalized Blood Pressure Targets Correlates with Worse Outcome after Successful Recanalization
Deviation from Personalized Blood Pressure Targets Correlates with Worse Outcome after Successful Recanalization Open
Background Personalized blood pressure (BP) management for acute ischemic stroke patients after successful recanalization lacks evidence. Our study aimed to investigate whether the deviation of BP from cerebral autoregulation (CA) limits, …
View article: Detailed phenotype of <i>RNF213</i> p.R4810K variant identified by the Chinese patients with acute ischaemic stroke or transient ischaemic attack
Detailed phenotype of <i>RNF213</i> p.R4810K variant identified by the Chinese patients with acute ischaemic stroke or transient ischaemic attack Open
Background and purpose The ring finger protein 213 gene ( RNF213 ) p.R4810K variant increased the risk of acute ischaemic stroke (AIS) attributable to intracranial arterial stenosis (ICAS) in the Japanese and Korean populations. In this st…
View article: Brain symmetry index predicts 3-month mortality in patients with acute large hemispheric infarction
Brain symmetry index predicts 3-month mortality in patients with acute large hemispheric infarction Open
Quantitative electroencephalography data are helpful to predict outcomes of cerebral infarction patients. The study was performed to evaluate the value of brain symmetry index by quantitative electroencephalography in predicting 3-month mo…
View article: Increased serum uric acid level is associated with better outcome after endovascular treatment for acute ischemic stroke—a prospective cohort study
Increased serum uric acid level is associated with better outcome after endovascular treatment for acute ischemic stroke—a prospective cohort study Open
Among patients with acute LVO type of stroke who received EVT, baseline high SUA level may predict a better 90-day functional outcome.
View article: Nocturnal High Systolic Blood Pressure is Associated with Poor Discharge Outcome in Spontaneous Subarachnoid Hemorrhage Patients: Results from the Chinese Stroke Center Alliance Study
Nocturnal High Systolic Blood Pressure is Associated with Poor Discharge Outcome in Spontaneous Subarachnoid Hemorrhage Patients: Results from the Chinese Stroke Center Alliance Study Open
Background and purpose Spontaneous subarachnoid hemorrhage is a neurological emergency with high mortality and disability. Hypertensive states are related to a bad prognosis and a higher risk of rebleeding. However, the relationship betwee…
View article: Posterior circulation stroke due to intracranial artery disease in the Chinese population
Posterior circulation stroke due to intracranial artery disease in the Chinese population Open
Background Little is known about the distribution of the intracranial arteries that are responsible for noncardiogenic posterior circulation stroke (PCS) in the Chinese population. Furthermore, few studies have compared the imaging manifes…
View article: The role of hypertension and diabetes mellitus on the etiology of middle cerebral artery disease
The role of hypertension and diabetes mellitus on the etiology of middle cerebral artery disease Open
Background Ischemic stroke (IS) caused by middle cerebral artery (MCA) disease is the most common type of IS caused by intracranial artery disease in the Chinese population. Hypertension and diabetes mellitus are the common risk factors of…
View article: Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients
Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients Open
Background Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high disability and mortality. MicroRNAs (miRNAs) are reported to play a modulating role in aSAH. We investigated specific plasma microRNAs (miRNAs) …
View article: Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion
Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion Open
Background and purpose It remains controversial if endovascular treatment (EVT) can improve the outcome of patients with acute basilar artery occlusion (BAO). This study aims to compare the functional outcomes between EVT with and without …
View article: The change index of quantitative electroencephalography for evaluating the prognosis of large hemispheric infarction
The change index of quantitative electroencephalography for evaluating the prognosis of large hemispheric infarction Open
A growing number of studies have demonstrated the role of quantitative electroencephalography in assessing brain function in neuro-intensive care units. Still, few studies have examined patients with large hemisphere infarction. Thirty pat…
View article: Haemostatic therapy in spontaneous intracerebral haemorrhage patients with high-risk of haematoma expansion by CT marker: a systematic review and meta-analysis of randomised trials
Haemostatic therapy in spontaneous intracerebral haemorrhage patients with high-risk of haematoma expansion by CT marker: a systematic review and meta-analysis of randomised trials Open
Background and purpose Current randomised controlled trials (RCTs) showed an uncertain benefit of haemostatic therapy on preventing haematoma expansion and improving the outcome in patients with intracerebral haemorrhage (ICH). This meta-a…
View article: Tranexamic acid for acute intracerebral haemorrhage growth based on imaging assessment (TRAIGE): a multicentre, randomised, placebo-controlled trial
Tranexamic acid for acute intracerebral haemorrhage growth based on imaging assessment (TRAIGE): a multicentre, randomised, placebo-controlled trial Open
Background Studies show tranexamic acid can reduce the risk of death and early neurological deterioration after intracranial haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma expansion and improves outcome in intrac…
View article: Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status
Adverse Outcomes Associated With Higher Mean Blood Pressure and Greater Blood Pressure Variability Immediately After Successful Embolectomy in Those With Acute Ischemic Stroke, and the Influence of Pretreatment Collateral Circulation Status Open
Background To investigate whether collateral status could modify the associations between post‐thrombectomy blood pressure (BP) measures and outcomes. Methods and Results Patients with anterior‐circulation large‐vessel‐occlusion successful…
View article: Prior Antithrombotic Therapy is Associated with Increased Risk of Death in Patients with Intracerebral Hemorrhage: Findings from the Chinese Stroke Center Alliance (CSCA) Study
Prior Antithrombotic Therapy is Associated with Increased Risk of Death in Patients with Intracerebral Hemorrhage: Findings from the Chinese Stroke Center Alliance (CSCA) Study Open
The association of preceding antithrombotic therapy with outcomes of patients with intracerebral hemorrhage (ICH) has not been well clarified. We investigated the characteristics and associations of prior antithrombotic therapy (oral antic…
View article: Intracranial Atherosclerosis Coexisting With White Matter Hyperintensities May Predict Unfavorable Functional Outcome in Patients With Acute Cerebral Ischemia
Intracranial Atherosclerosis Coexisting With White Matter Hyperintensities May Predict Unfavorable Functional Outcome in Patients With Acute Cerebral Ischemia Open
Background and Purpose: This study aimed to assess the effect of baseline white matter hyperintensities (WMH) on 1-year stroke recurrence and the functional outcome for patients with intracranial atherosclerosis (ICAS). Methods: We analyze…
View article: Plaque morphology in acute symptomatic intracranial atherosclerotic disease
Plaque morphology in acute symptomatic intracranial atherosclerotic disease Open
Background Intracranial atherosclerotic disease (ICAD) is globally a major ischaemic stroke subtype with high recurrence. Understanding the morphology of symptomatic ICAD plaques, largely unknown by far, may help identify vulnerable lesion…
View article: Cortical Microinfarcts Associated With Worse Outcomes in Patients With Acute Ischemic Stroke Receiving Endovascular Treatment
Cortical Microinfarcts Associated With Worse Outcomes in Patients With Acute Ischemic Stroke Receiving Endovascular Treatment Open
Background and Purpose: We aimed to evaluate the impact of cortical microinfarcts (CMIs) on functional outcome after endovascular treatment in patients with acute ischemic stroke. Methods: In a multicenter registration study for RESCUE-RE …
View article: Concurrent intracranial and extracranial artery stenosis and the prognosis of transient ischaemic symptoms or imaging-negative ischaemic stroke
Concurrent intracranial and extracranial artery stenosis and the prognosis of transient ischaemic symptoms or imaging-negative ischaemic stroke Open
Background and purpose Transient ischaemic attack (TIA), transient symptoms with infarction (TSI) and diffusion-weighted imaging (DWI)-negative acute ischaemic stroke (AIS) share similar aetiologies but are considered to have a rather beni…
View article: Hemodynamic Significance of Middle Cerebral Artery Stenosis Associated With the Severity of Ipsilateral White Matter Changes
Hemodynamic Significance of Middle Cerebral Artery Stenosis Associated With the Severity of Ipsilateral White Matter Changes Open
Background: Previous studies conflicted in the association between intracranial atherosclerotic stenosis (ICAS) and the severity of white matter changes (WMC). Aims: We aimed to investigate the relationships between the severity of luminal…
View article: Causal relationship between neuronal activity and cerebral hemodynamics in patients with ischemic stroke
Causal relationship between neuronal activity and cerebral hemodynamics in patients with ischemic stroke Open
A causal relationship from EEG→FV may exist in patients with ischemic stroke. The strength of G-causality may be related to stroke severity at discharge.
View article: Clinical, imaging features and outcome in internal carotid artery versus middle cerebral artery disease
Clinical, imaging features and outcome in internal carotid artery versus middle cerebral artery disease Open
The clinical, radiologic characteristics and outcome are distinctively different between ICA and MCA disease. Compared to MCA disease, ICA disease has more serious clinical and radiologic manifestation, and poorer outcome.
View article: Cerebral Hemodynamic Evaluation After Cerebral Recanalization Therapy for Acute Ischemic Stroke
Cerebral Hemodynamic Evaluation After Cerebral Recanalization Therapy for Acute Ischemic Stroke Open
Cerebral recanalization therapy, either intravenous thrombolysis or mechanical thrombectomy, improves the outcomes in patients with acute ischemic stroke (AIS) by restoring the cerebral perfusion of the ischemic penumbra. Cerebral hemodyna…