Shiying Yu
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View article: SWE-Compass: Towards Unified Evaluation of Agentic Coding Abilities for Large Language Models
SWE-Compass: Towards Unified Evaluation of Agentic Coding Abilities for Large Language Models Open
Evaluating large language models (LLMs) for software engineering has been limited by narrow task coverage, language bias, and insufficient alignment with real-world developer workflows. Existing benchmarks often focus on algorithmic proble…
View article: Identification of key genes and signaling pathways of liver cancer and model construction for prognosis and diagnosis based on bioinformatics analysis
Identification of key genes and signaling pathways of liver cancer and model construction for prognosis and diagnosis based on bioinformatics analysis Open
Objective This study aims to identify key genes, biomarkers, and associated signaling pathways involved in liver cancer progression by analyzing differentially expressed genes (DEGs) between normal and cancerous liver tissues, with the goa…
View article: Complex-Valued Optoelectronic Hybrid Neural Networks For Image Classification Based on Optical 4f Systems
Complex-Valued Optoelectronic Hybrid Neural Networks For Image Classification Based on Optical 4f Systems Open
View article: Functional Genomics of Root Development in <i>Populus</i> and Its Ecological Implications
Functional Genomics of Root Development in <i>Populus</i> and Its Ecological Implications Open
View article: Genetic Basis of Growth Traits in Shrimp Based on QTL and GWAS Studies
Genetic Basis of Growth Traits in Shrimp Based on QTL and GWAS Studies Open
View article: Preliminary study on the cellular and molecular mechanisms of Cms1 ribosomal small subunit homolog promoting hepatocellular carcinoma progression via activation of the homolog family member A/yes-associated protein 1 signaling pathway
Preliminary study on the cellular and molecular mechanisms of Cms1 ribosomal small subunit homolog promoting hepatocellular carcinoma progression via activation of the homolog family member A/yes-associated protein 1 signaling pathway Open
Objective: The precise mechanism of action of cms1 ribosomal small subunit homolog (CMSS1) in hepatocellular carcinoma (HCC) is yet unknown, although it may be essential to the malignant evolution of disease. The aim of this study was to r…
View article: Covalent Bonding of MXene/COF Heterojunction for Ultralong Cycling Li-Ion Battery Electrodes
Covalent Bonding of MXene/COF Heterojunction for Ultralong Cycling Li-Ion Battery Electrodes Open
Covalent organic frameworks (COFs) have emerged as promising renewable electrode materials for LIBs and gained significant attention, but their capacity has been limited by the densely packed 2D layer structures, low active site availabili…
View article: Socioeconomic Status as a Factor of Male Domestic Violence: Adaptations Due to Paternity Uncertainty Theory
Socioeconomic Status as a Factor of Male Domestic Violence: Adaptations Due to Paternity Uncertainty Theory Open
This article proposes the hypothesis that males of low socioeconomic status (SES) would more likely be a perpetrator of domestic violence due to selection pressures branching from paternity uncertainty. This article would address two point…
View article: The Role of High-Performance Computing in Modern Biology: Tackling Big Data Challenges
The Role of High-Performance Computing in Modern Biology: Tackling Big Data Challenges Open
View article: The Classification Study and Categorization of Medicinal Properties in Traditional Chinese Medicine
The Classification Study and Categorization of Medicinal Properties in Traditional Chinese Medicine Open
Traditional Chinese medicine (TCM), as a significant component of Chinese traditional medicine, has accumulated rich knowledge and experience over thousands of years of history. Different categories of TCM play unique roles and have specif…
View article: Efficacy and safety of Genolimzumab in previously treated PD-L1-Positive recurrent or metastatic cervical cancer: a multicenter open-label, single-arm, phase Ⅱ study
Efficacy and safety of Genolimzumab in previously treated PD-L1-Positive recurrent or metastatic cervical cancer: a multicenter open-label, single-arm, phase Ⅱ study Open
Purpose This phase II trial investigated the efficacy and safety of Genolimzumab (GB226) in patients with previously treated, PD-L1-Positive recurrent or metastatic cervical cancer. Methods We conducted a two-stage, phase II trial to enrol…
View article: The Essential Network (TEN): engagement and mental health insights from a digital mental health assessment tool for Australian health professionals during COVID-19
The Essential Network (TEN): engagement and mental health insights from a digital mental health assessment tool for Australian health professionals during COVID-19 Open
Background Health professionals are at risk of poor mental health outcomes due to the COVID-19 pandemic. The Essential Network (TEN) is a blended care mental health support service for Australian health professionals, funded by the Austral…
View article: Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1
Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1 Open
Skeletal muscle wasting is the most remarkable phenotypic feature of cancer cachexia that increases the risk of morbidity and mortality. However, there are currently no effective drugs against cancer cachexia. Ursolic acid (UA) is a lipoph…
View article: Supplementary figure, tables and information from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Supplementary figure, tables and information from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer Open
Supplementary Figure 1 HN31 cells with BAP1 vector control, knockdown, and wild-type variants were immunoblotted for the expression of various proteins associated with the DNA damage response (both homologous recombination [BAP1] and non-h…
View article: Data from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Data from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer Open
Purpose: This study examined the potential role of the nuclear deubiquitinating enzyme BRCA1-associated protein-1 (BAP1) in radioresistance in head and neck squamous cell cancer (HNSCC).Experimental Design: We overexpressed, …
View article: Data from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Data from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer Open
Purpose: This study examined the potential role of the nuclear deubiquitinating enzyme BRCA1-associated protein-1 (BAP1) in radioresistance in head and neck squamous cell cancer (HNSCC).Experimental Design: We overexpressed, …
View article: Supplementary figure, tables and information from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Supplementary figure, tables and information from BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer Open
Supplementary Figure 1 HN31 cells with BAP1 vector control, knockdown, and wild-type variants were immunoblotted for the expression of various proteins associated with the DNA damage response (both homologous recombination [BAP1] and non-h…
View article: Advances in pharmacotherapies in cancer-related cachexia*
Advances in pharmacotherapies in cancer-related cachexia* Open
Cancer-related cachexia is highly prevalent in patients with advanced cancer, affecting approximately 50%-80% of patients and seriously interfering with active therapy, quality of life, and survival time. There are currently no effective t…
View article: Research progress on immune checkpoint inhibitors in neoadjuvant therapy for gastric cancer
Research progress on immune checkpoint inhibitors in neoadjuvant therapy for gastric cancer Open
In recent years, immune checkpoint inhibitors (ICIs) have become an important treatment strategy for advanced gastric cancer. Immunotherapy has gradually transitioned from a later-line to a first-line treatment for advanced gastric cancer.…
View article: GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis
GTF2E2 is a novel biomarker for recurrence after surgery and promotes progression of esophageal squamous cell carcinoma via miR-139-5p/GTF2E2/FUS axis Open
View article: Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting Open
Background: Cachexia is a multifactorial disorder characterized by weight loss and muscle wasting, making up for about 20% of cancer-related death. However, there are no effective drugs to combat cachexia at present. Methods: In this study…
View article: Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ
Preclinical Investigation of Alpinetin in the Treatment of Cancer-Induced Cachexia via Activating PPARγ Open
The ongoing loss of skeletal muscle is a central event of cancer cachexia, and its consequences include adverse effects on patient’s quality of life and survival. Alpinetin (Alp), a natural plant-derived flavonoid obtained from Alpinia kat…
View article: Corrigendum to “Performance of Distress Thermometer and Associated Factors of Psychological Distress among Chinese Cancer Patients”
Corrigendum to “Performance of Distress Thermometer and Associated Factors of Psychological Distress among Chinese Cancer Patients” Open
[This corrects the article DOI: 10.1155/2020/3293589.].
View article: The efficiency of distress thermometer in the determination of supporting needs for cancer inpatients
The efficiency of distress thermometer in the determination of supporting needs for cancer inpatients Open
Psychological distress scale is highly recommended for cancer patients' care. Several psychological scales have been implemented in cancer outpatient clinics. However, the use of the psychological distress scale, particularly distress ther…
View article: Performance of Distress Thermometer and Associated Factors of Psychological Distress among Chinese Cancer Patients
Performance of Distress Thermometer and Associated Factors of Psychological Distress among Chinese Cancer Patients Open
Objective . We aimed to examine the performance of the distress thermometer (DT) and identify the prevalence and risk factors associated with psychological distress (PD) in heterogeneous cancer patients. Methods . This cross-sectional stud…
View article: Mental health status of cancer caregivers, assessment tools, and psychological interventions*
Mental health status of cancer caregivers, assessment tools, and psychological interventions* Open
Many studies pointed out that psychological pain is not limited to the cancer patients themselves, but their caregivers also experience different levels of psychological problems such as depression, anxiety, and stress. This article attemp…
View article: Assessing anxiety, depression, and stress among inpatients with cancer*
Assessing anxiety, depression, and stress among inpatients with cancer* Open
Objective This study aimed to assess anxiety, depression, and stress among inpatients with cancer. Methods Two hundred thirty-five hospitalized patients with cancer were surveyed with the Depression Anxiety Stress Scales (simplified Chines…
View article: Genetic alterations and expression characteristics of ARID1A impact tumor immune contexture and survival in early-onset gastric cancer.
Genetic alterations and expression characteristics of ARID1A impact tumor immune contexture and survival in early-onset gastric cancer. Open
The AT-rich Interactive Domain 1A (ARID1A) is one of the most frequently mutated genes in gastric cancer. Here, we found that genetic variants in noncoding regions of ARID1A associated with altered protein levels by target sequencing. Nota…
View article: Bevacizumab Plus Erlotinib in Chinese Patients with Untreated, <i>EGFR</i>-Mutated, Advanced NSCLC (ARTEMIS-CTONG1509): A Multicenter Phase 3 Study
Bevacizumab Plus Erlotinib in Chinese Patients with Untreated, <i>EGFR</i>-Mutated, Advanced NSCLC (ARTEMIS-CTONG1509): A Multicenter Phase 3 Study Open
View article: Oral vinorelbine versus intravenous vinorelbine, in combination with epirubicin as first-line chemotherapy in Chinese patients with metastatic breast cancer
Oral vinorelbine versus intravenous vinorelbine, in combination with epirubicin as first-line chemotherapy in Chinese patients with metastatic breast cancer Open
Oral VRL offers easier administration, better quality of life, and cost saving. This study aimed to evaluate the treatment efficacy in terms of tumor response of the two formulations of vinorelbine (VRL, oral and IV) in combination with ep…