Yuanjun Zeng
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View article: LncRNA16 inhibits pyroptosis and promotes platinum resistance in non-small cell lung cancer by sponging miRNA1827 to regulate MBD3/GSDME expression
LncRNA16 inhibits pyroptosis and promotes platinum resistance in non-small cell lung cancer by sponging miRNA1827 to regulate MBD3/GSDME expression Open
We identified a novel function of lncRNA16 in inhibiting pyroptosis and proposed an effective therapeutic drug, the miRNA1827 agomir, for chemosensitization. This study offers a potential strategy for treating patients with NSCLC, especial…
View article: A single residue switch mediates the broad neutralization of Rotaviruses
A single residue switch mediates the broad neutralization of Rotaviruses Open
Broadly neutralizing antibodies (bNAbs) could offer escape-tolerant and lasting protection against viral infections and therefore guide development of broad-spectrum vaccines. The increasing challenge posed by viral evolution and immune ev…
View article: The Association Between Metabolic Score for Visceral Fat and Cognitive Function Among Older Adults in the United States
The Association Between Metabolic Score for Visceral Fat and Cognitive Function Among Older Adults in the United States Open
Background: Although several studies have demonstrated a link between obesity and cognitive function, the majority have primarily utilized body mass index (BMI) and waist circumference, ignoring the distribution of body fat. Evidence regar…
View article: Estimating the prevalence of six common respiratory viral infections in Zhangzhou, China using nasopharyngeal swabs in adults and throat swabs in Children
Estimating the prevalence of six common respiratory viral infections in Zhangzhou, China using nasopharyngeal swabs in adults and throat swabs in Children Open
Acute respiratory viral infections are a major public health concern worldwide, causing significant morbidity and economic burden. Understanding the epidemiological characteristics of these infections is crucial for effective control and p…
View article: Targeted plasma metabolomics reveals potential biomarkers of the elderly with mild cognitive impairment in Qingdao rural area
Targeted plasma metabolomics reveals potential biomarkers of the elderly with mild cognitive impairment in Qingdao rural area Open
Introduction Previous research has suggested a link between the onset of Alzheimer’s disease (AD) and metabolic disorder; however, the findings have been inconsistent. To date, the majority of metabolomics studies have focused on AD, resul…
View article: Construction of fluorescence system of felodipine–tetracyanovinyl–2,2′-bipyridine complex
Construction of fluorescence system of felodipine–tetracyanovinyl–2,2′-bipyridine complex Open
Felodipine (FEL)–tetracyanoethylene (TCNE)–2,2′-bipyridine (Bpy) complex was prepared with FEL, TCNE–Bpy and characterized by fluorescence, ultraviolet, and infrared. By exploring the concentration and dosage of Bpy, it was found that 1 mL…
View article: GPI: An indicator for immune infiltrates and prognosis of human breast cancer from a comprehensive analysis
GPI: An indicator for immune infiltrates and prognosis of human breast cancer from a comprehensive analysis Open
Glucose-6-phosphate isomerase ( GPI ) plays an important part in gluconeogenesis and glycolysis through the interconversion of d -glucose-6-phosphate and d -fructose-6-phosphate, and its clinical significance still remains unclear in breas…
View article: Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses
Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses Open
Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development…
View article: Comprehensive Analysis of Prognostic and immune infiltrates for FOXPs Transcription Factors in Human Breast Cancer
Comprehensive Analysis of Prognostic and immune infiltrates for FOXPs Transcription Factors in Human Breast Cancer Open
Forkhead-box-P family include FOXP1/2/3/4 and its clinical significance still remains unclear in breast cancer (BRCA). We analysed the expressions of FOXPs in BRCA patients to determine diagnostic and prognostic values. Our results indicat…
View article: Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production
Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production Open
Non-replicating rotavirus vaccines are alternative strategies that may improve the protective efficacy of rotavirus vaccines in low- and middle-income countries. The truncated spike protein VP4 (aa26-476, VP4*)was a candidate antigen for t…
View article: Comprehensive Analysis of Prognostic And Immune Infiltrates For Foxps Transcription Factors In Human Breast Cancer
Comprehensive Analysis of Prognostic And Immune Infiltrates For Foxps Transcription Factors In Human Breast Cancer Open
Forkhead-box-P family include FOXP1/2/3/4 and its clinical significance still remains unclear in breast cancer(BRCA). We analysed the expressions of FOXPs in BRCA patients to determine diagnostic and prognostic values. Our results indicate…
View article: Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases
Inflammatory pseudotumor-like follicular dendritic cell sarcoma: A brief report of two cases Open
EBV probe-based in situ hybridization and detection of immunohistochemical markers of FDC play an important role in the diagnosis and differential diagnosis of inflammatory pseudotumor-like FDC sarcoma. Complete surgical excision co…
View article: Immunogenicity and protective efficacy of rotavirus VP8<b>*</b>fused to cholera toxin B subunit in a mouse model
Immunogenicity and protective efficacy of rotavirus VP8<b>*</b>fused to cholera toxin B subunit in a mouse model Open
In attempts to develop recombinant subunit vaccines against rotavirus disease, it was previously shown that the N-terminal truncated VP8* protein, VP8-1 (aa26-231), is a good vaccine candidate when used for immunization in combination with…