Yuan‐Wu Chen
YOU?
Author Swipe
View article: Prognostic Significance of Programmed Death-Ligand 1 Expression in Betel Nut Chewing Patients with Oral Squamous Cell Carcinoma
Prognostic Significance of Programmed Death-Ligand 1 Expression in Betel Nut Chewing Patients with Oral Squamous Cell Carcinoma Open
Objective: This study aimed to investigate the prognostic significance of programmed death-ligand 1 (PD-L1) expression in Taiwanese patients with oral squamous cell carcinoma (OSCC) who underwent surgical treatment, particularly in those w…
View article: Baohe Pingwei power plus neoadjuvant chemotherapy for gastric cancer
Baohe Pingwei power plus neoadjuvant chemotherapy for gastric cancer Open
BACKGROUND Neoadjuvant chemotherapy improves the resection rate and reduces postoperative recurrence in gastric cancer (GC) but is often associated with significant toxicity. Traditional Chinese medicine has unique advantages in the treatm…
View article: Hard and Soft Tissue Facial Landmarks for Mandibular Angle Reduction: A Clinical Study
Hard and Soft Tissue Facial Landmarks for Mandibular Angle Reduction: A Clinical Study Open
Background: Square faces, which are influenced by genetic factors and structural features, are considered undesirable among the Asian population. Surgical interventions, such as mandibular angle reduction, aim to alter these characteristic…
View article: Radiological Analysis of the Pterygomaxillary Junction for Orthognathic Surgical Precision and Safety: A Retrospective Study
Radiological Analysis of the Pterygomaxillary Junction for Orthognathic Surgical Precision and Safety: A Retrospective Study Open
Objectives: To investigate the parameters of pterygomaxillary suture (PMS), including thickness, height, and angulation, using computed tomography (CT) scans to enhance surgical precision and maximize the safety of patients during Le Fort …
View article: Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis
Allyl Isothiocyanate Suppresses the Proliferation in Oral Squamous Cell Carcinoma via Mediating the KDM8/CCNA1 Axis Open
The dysregulated expression of cyclin genes can lead to the uncontrolled proliferation of cancer cells. Histone demethylase Jumonji-C domain-containing protein 5 (KDM8, JMJD5) and cyclin A1 (CCNA1) are pivotal in cell cycle progression. A …
View article: Allyl isothiocyanate suppressed the proliferation of oral squamous cell carcinoma in vitro, in vivo, and in patient-derived tumor xenografts by downregulating the KDM8/CCNA1 axis
Allyl isothiocyanate suppressed the proliferation of oral squamous cell carcinoma in vitro, in vivo, and in patient-derived tumor xenografts by downregulating the KDM8/CCNA1 axis Open
Background: Previous studies have shown that many cruciferous vegetables have anticancer effects, which can be connected with the presence of allyl isothiocyanate (AITC). Histone demethylase KDM8 and cyclin A1 (CCNA1) were required for cel…
View article: Regenerative Efficacy of Supercritical Carbon Dioxide-Derived Bone Graft Putty in Rabbit Bone Defect Model
Regenerative Efficacy of Supercritical Carbon Dioxide-Derived Bone Graft Putty in Rabbit Bone Defect Model Open
Bone defects can arise from numerous reasons, such as aging, tumor, trauma, infection, surgery, and congenital diseases. Bone grafts are commonly used as a substitute to fill the void and regenerate the defect. Due to its clean and green t…
View article: Association between socioeconomic status and severity of oral epithelial dysplasia using a Taiwanese Nationwide Oral Mucosal Screening Program: a retrospective analysis
Association between socioeconomic status and severity of oral epithelial dysplasia using a Taiwanese Nationwide Oral Mucosal Screening Program: a retrospective analysis Open
View article: Levitt’s CO breath test in the differential diagnosis of chronic isolated hyperbilirubinemia
Levitt’s CO breath test in the differential diagnosis of chronic isolated hyperbilirubinemia Open
A key component of the differential diagnosis of isolated hyperbilirubinemia (HB) is distinguishing between hemolytic and non-hemolytic types. Routine hemolysis screening markers have unsatisfactory sensitivity and specificity. Erythrocyte…
View article: Association Between Socioeconomic Status and Severity of Oral Epithelial Dysplasia Using a Taiwanese Nationwide Oral Mucosal Screening Program: A Retrospective Analysis
Association Between Socioeconomic Status and Severity of Oral Epithelial Dysplasia Using a Taiwanese Nationwide Oral Mucosal Screening Program: A Retrospective Analysis Open
Background: The study aimed to investigate the association between socioeconomic status and severity of oral epithelial dysplasia (OED) using current data from the Taiwanese Nationwide Oral Mucosal Screening Program (TNOMSP). Methods: This…
View article: Pretreatment Body Mass Index and Serum Uric Acid and Albumin Levels as Prognostic Predictors in Patients with Oral Squamous Cell Carcinoma
Pretreatment Body Mass Index and Serum Uric Acid and Albumin Levels as Prognostic Predictors in Patients with Oral Squamous Cell Carcinoma Open
Background: Oral squamous cell carcinoma (OSCC) is the most frequently found malignant tumor of the oral cavity, and the annual death rate of OSCC patients has been increasing rapidly among the Taiwanese population. Aim: The aim of this st…
View article: Submental and submandibular swelling should be checked before extubation in oral and neck surgery
Submental and submandibular swelling should be checked before extubation in oral and neck surgery Open
View article: Comparison of the accuracy of diagnoses of oral potentially malignant disorders with dysplasia by a general dental clinician and a specialist using the Taiwanese Nationwide Oral Mucosal Screening Program
Comparison of the accuracy of diagnoses of oral potentially malignant disorders with dysplasia by a general dental clinician and a specialist using the Taiwanese Nationwide Oral Mucosal Screening Program Open
Screening for oral potentially malignant disorders (OPMDs) with dysplasia in high-risk groups is suggested in countries with a high prevalence of the disorders. This study aimed to compare the accuracy of diagnoses of OPMDs with dysplasia …
View article: Triptolide suppresses oral cancer cell PD-L1 expression in the interferon-γ-modulated microenvironment in vitro, in vivo, and in clinical patients
Triptolide suppresses oral cancer cell PD-L1 expression in the interferon-γ-modulated microenvironment in vitro, in vivo, and in clinical patients Open
Biological and prognostic roles of programmed death ligand 1 (PD-L1) remain unclear in oral squamous cell carcinoma (OSCC). Moreover, the pivotal role of tumor microenvironmental interferon-gamma (IFN-γ) in host responses to malignant cell…
View article: Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model
Downregulation of Jumonji-C domain-containing protein 5 inhibits proliferation by silibinin in the oral cancer PDTX model Open
Dysregulation of histone demethylase Jumonji-C domain-containing protein 5 (JMJD5) has been identified as a great effect on tumorigenesis. Silibinin is a commonly used anti-hepatotoxic drug and exhibits anticancer effect in various cancers…
View article: Effects of lung protective ventilation on postoperative pulmonary outcomes for prolonged oral cancer combined with free flap surgery
Effects of lung protective ventilation on postoperative pulmonary outcomes for prolonged oral cancer combined with free flap surgery Open
The intraoperative lung protective ventilation with low tidal volume, positive end expiratory pressure (PEEP) and intermittent lungs recruitment was found to decrease postoperative pulmonary complications. In this retrospective medical rec…
View article: Pretreatment body mass index as a prognostic predictor in patients with oral squamous cell carcinoma
Pretreatment body mass index as a prognostic predictor in patients with oral squamous cell carcinoma Open
Objectives To evaluate whether low body mass index (BMI) is a potential adverse prognostic factor in patients with oral squamous cell carcinoma (OSCC). Material and methods This cross-sectional study included 320 patients with OSCC who und…
View article: A histopathological evaluation and potential prognostic implications of oral squamous cell carcinoma with adverse features
A histopathological evaluation and potential prognostic implications of oral squamous cell carcinoma with adverse features Open
When determining survival prognosis for patients with a pN0 status, we recommended including all adverse features. In contrast, extranodal extension was the most important prognostic factor for patients with a pN+ status.
View article: Huge lipoma in the left submandibular region
Huge lipoma in the left submandibular region Open
View article: Knee joint injection resveratrol amelioration inflammation in collagen antibody induced arthritis
Knee joint injection resveratrol amelioration inflammation in collagen antibody induced arthritis Open
Background: Resveratrol has been considered to possess anti-inflammatory properties. Here, we propose that intra-articular resveratrol injection might ameliorate acute inflammation in a single knee joint in mice with collagen antibody-indu…
View article: Triptolide Suppress Oral Cancer Cell PD-L1 Expression in the Interferon Gamma Modulated Microenvironment <i>in vitro, in vivo</i> and <i>in clinical</i>
Triptolide Suppress Oral Cancer Cell PD-L1 Expression in the Interferon Gamma Modulated Microenvironment <i>in vitro, in vivo</i> and <i>in clinical</i> Open
View article: Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model
Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model Open
Background Aberrant expression of decoy receptor 3 (DcR3) is considered to be a diagnostic and therapeutic target for human cancers. The aim of this study was to assess DcR3 as a target of the anticancer effects of triptolide (TPL) in prec…
View article: Comparative evaluation of autofluorescence imaging and histopathological investigation for oral potentially malignant disorders in Taiwan
Comparative evaluation of autofluorescence imaging and histopathological investigation for oral potentially malignant disorders in Taiwan Open
Autofluorescence imaging is a useful adjunct that can assist specialists in assessing OPMD patients prone to dysplasia without compromising patient care.
View article: Langerhans cell histiocytosis at the right mandible
Langerhans cell histiocytosis at the right mandible Open
View article: Mouth-opening device as a treatment modality in trismus patients with head and neck cancer and oral submucous fibrosis: a prospective study
Mouth-opening device as a treatment modality in trismus patients with head and neck cancer and oral submucous fibrosis: a prospective study Open
This newly designed open-mouth exercise device can facilitate trismus patients with H&N cancer and OSF and improve mouth-opening range and quality of life.
View article: Full mouth reconstruction with immediate implant placement in multiple extraction sockets
Full mouth reconstruction with immediate implant placement in multiple extraction sockets Open
Fig. 1 (AeE) Multiple missing teeth and residual roots were revealed with poor oral hygiene and loss of vertical dimension.(FeJ) Atraumatic dental extraction of multiple residual roots followed by immediate implant placement was performed …
View article: Danshen extract circumvents drug resistance and represses cell growth in human oral cancer cells
Danshen extract circumvents drug resistance and represses cell growth in human oral cancer cells Open
View article: The nasolabial subcutaneous pedicle flap for lower-lip defect reconstruction
The nasolabial subcutaneous pedicle flap for lower-lip defect reconstruction Open
View article: Comprehensive orthognathic correction of post-traumatic Le-Fort II deformity
Comprehensive orthognathic correction of post-traumatic Le-Fort II deformity Open
View article: Lymph node density as a prognostic predictor in patients with betel nut-related oral squamous cell carcinoma
Lymph node density as a prognostic predictor in patients with betel nut-related oral squamous cell carcinoma Open