Yuanyi Yue
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View article: The status and influencing factors of COVID-19 vaccination in patients with COPD
The status and influencing factors of COVID-19 vaccination in patients with COPD Open
View article: <i>SCARF2</i> is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation
<i>SCARF2</i> is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation Open
Age‐related chronic inflammatory lung diseases impose a threat on public health, including idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). However, their etiology and potential targets have not been cl…
View article: Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS)
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-generation sequencing (mNGS) Open
Objective: Inhaled corticosteroids (ICS) are widely used in chronic obstructive pulmonary disease (COPD) patients as a treatment option. However, ICS may also increase the risk of pneumonia and alter the composition of airway microbiota. I…
View article: Copper homeostasis dysregulation in respiratory diseases: a review of current knowledge
Copper homeostasis dysregulation in respiratory diseases: a review of current knowledge Open
Cu is an essential micronutrient for various physiological processes in almost all human cell types. Given the critical role of Cu in a wide range of cellular processes, the local concentrations of Cu and the cellular distribution of Cu tr…
View article: Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review
Imbalance of gut microbiota is involved in the development of chronic obstructive pulmonary disease: A review Open
Chronic obstructive pulmonary disease (COPD) is a common chronic disease characterized by chronic airway inflammation and remodeling, which seriously endangers human health. Recent developments in genomics and metabolomics have revealed th…
View article: STAT3 regulates 5‐Fu resistance in human colorectal cancer cells by promoting Mcl‐1–dependent cytoprotective autophagy
STAT3 regulates 5‐Fu resistance in human colorectal cancer cells by promoting Mcl‐1–dependent cytoprotective autophagy Open
Chemoresistance to 5‐fluorouracil (5‐Fu)‐based chemotherapy is one of the primary reasons for the failure of colorectal cancer (CRC) management. STAT3 can mediate tumor drug resistance through a variety of diverse mechanisms. Nonetheless, …
View article: Prediction of Prognosis in Crohn's Disease Patients by Clinical Combined Feature Sets Through Advanced Machine Learning
Prediction of Prognosis in Crohn's Disease Patients by Clinical Combined Feature Sets Through Advanced Machine Learning Open
View article: Clusterin as a serum biomarker candidate contributes to the lung fibroblasts activation in chronic obstructive pulmonary disease
Clusterin as a serum biomarker candidate contributes to the lung fibroblasts activation in chronic obstructive pulmonary disease Open
Background: Fibrosis in the peripheral airways contributes to airflow limitation in patients with chronic obstructive pulmonary disease (COPD). However, the key proteins involved in its development are still poorly understood. Thus, we aim…
View article: CX3CR1 Acts as a Protective Biomarker in the Tumor Microenvironment of Colorectal Cancer
CX3CR1 Acts as a Protective Biomarker in the Tumor Microenvironment of Colorectal Cancer Open
The tumor microenvironment (TME) plays an important role in the pathogenesis of many cancers. We aimed to screen the TME-related hub genes of colorectal adenoma (CRAD) and identify possible prognostic biomarkers. The gene expression profil…
View article: all_cancer.rar
all_cancer.rar Open
The dataset for all cancers.
View article: IP<sub>3</sub>R attenuates oxidative stress and inflammation damage in smoking‐induced COPD by promoting autophagy
IP<sub>3</sub>R attenuates oxidative stress and inflammation damage in smoking‐induced COPD by promoting autophagy Open
Tobacco smoking is one of the most important risk factors for chronic obstructive pulmonary disease (COPD). However, the most critical genes and proteins remain poorly understood. Therefore, we aimed to investigate these hub genes and prot…
View article: Neurotrophic factor levels in the serum and cerebrospinal fluid of neonates infected with human cytomegalovirus
Neurotrophic factor levels in the serum and cerebrospinal fluid of neonates infected with human cytomegalovirus Open
Human cytomegalovirus (HCMV) is most likely to damage the central nervous system (CNS) during early embryonic development; however, the early neurodevelopmental abnormalities caused by HCMV infection and the regulation of cytokines remain …
View article: <p>Gene Expression Along with Genomic Copy Number Variation and Mutational Analysis Were Used to Develop a 9-Gene Signature for Estimating Prognosis of COAD</p>
Gene Expression Along with Genomic Copy Number Variation and Mutational Analysis Were Used to Develop a 9-Gene Signature for Estimating Prognosis of COAD Open
In this study, 9-gene signature is constructed as a new prognostic marker to predict the survival of COAD patients.
View article: Editing and Expression of miR-589-5p as an Important Biomarker in Colorectal Cancer
Editing and Expression of miR-589-5p as an Important Biomarker in Colorectal Cancer Open
Objectives: Colorectal cancer (CRC) is recognized as the third most common cancer worldwide. Recently, emerging evidence showed that microRNA (miRNA) A-to-I editing plays crucial roles in cancer prognosis as well as cancer therapy. However…
View article: Prediction of COVID-19 Severity Using Chest Computed Tomography and Laboratory Measurements: Evaluation Using a Machine Learning Approach
Prediction of COVID-19 Severity Using Chest Computed Tomography and Laboratory Measurements: Evaluation Using a Machine Learning Approach Open
Background Most of the mortality resulting from COVID-19 has been associated with severe disease. Effective treatment of severe cases remains a challenge due to the lack of early detection of the infection. Objective This study aimed to de…
View article: Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions
Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions Open
COVID-19 (Coronavirus Disease 2019) has been an ongoing pandemic, resulting in an increase in people being infected globally. Understanding the potential risk of infection for people under different respiratory system conditions is importa…
View article: STAT1 expression and HPV16 viral load predict cervical lesion progression
STAT1 expression and HPV16 viral load predict cervical lesion progression Open
Cervical cancer is the fourth leading cause of cancer-associated mortality worldwide. However, its underlying molecular mechanisms are unclear. It is important to explore these mechanisms in order to identify novel diagnostic and prognosti…
View article: Bibliometric analysis of subject trends and knowledge structures of gut microbiota
Bibliometric analysis of subject trends and knowledge structures of gut microbiota Open
Some subjects were not yet fully studied according to the strategic coordinates; and the emerging hotspots in the social network map can be considered as directions of future research.
View article: Prediction of COVID-19 Severity Using Chest Computed Tomography and Laboratory Measurements: Evaluation Using a Machine Learning Approach (Preprint)
Prediction of COVID-19 Severity Using Chest Computed Tomography and Laboratory Measurements: Evaluation Using a Machine Learning Approach (Preprint) Open
BACKGROUND Most of the mortality resulting from COVID-19 has been associated with severe disease. Effective treatment of severe cases remains a challenge due to the lack of early detection of the infection. OBJECTIVE This study aimed to…
View article: Electronic cigarettes: Emerging trends and research hotspots
Electronic cigarettes: Emerging trends and research hotspots Open
Results suggest that some currently immature topics in strategic coordinates and emerging hotspots in social network graphs can be used as future research directions.