Xiao Hu
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View article: Effects of Functional Foods and Dietary Bioactives on Human Health
Effects of Functional Foods and Dietary Bioactives on Human Health Open
Functional foods and dietary bioactives are moving from discovery to translation because we can now engineer structure and exposure together—the two levers that largely determine real-world efficacy [...]
View article: A Hybrid G-Quadruplex Structure Formed by a Sequence from the MAX Gene
A Hybrid G-Quadruplex Structure Formed by a Sequence from the MAX Gene Open
View article: An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy
An induced pluripotent stem cell-based chemical genetic approach for studying spinal muscular atrophy Open
Spinal muscular atrophy (SMA) is a genetic disease characterized by degeneration of spinal cord motor neurons and neuromuscular junctions. Despite recent development in therapies for SMA, treatment efficacy largely relies on administration…
View article: A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade
A novel long-acting C5a-blocking cyclic peptide prevents sepsis-induced organ dysfunction via effective blockade of the inflammatory cascade Open
View article: Epidemiological, clinical, and molecular characteristics of coxsackievirus A2 infections during a herpangina outbreak in children on an Island in Eastern China in 2024: a surveillance-based study
Epidemiological, clinical, and molecular characteristics of coxsackievirus A2 infections during a herpangina outbreak in children on an Island in Eastern China in 2024: a surveillance-based study Open
CV-A2 has re-emerged as the dominant herpangina-associated enterovirus in Eastern China, demonstrating distinct clinical and hematological features. This shift in serotype prevalence underscores the need for continued surveillance to monit…
View article: Temporal Evolution and Numerical Simulation of Water-Sensitive Reservoirs During Long-Term Waterflooding: A Case Study of the North 31 Wutonggou Formation
Temporal Evolution and Numerical Simulation of Water-Sensitive Reservoirs During Long-Term Waterflooding: A Case Study of the North 31 Wutonggou Formation Open
This study addresses the challenges of uneven recovery in strongly water-sensitive reservoirs through the development of a time-dependent two-phase flow model capturing the dynamic evolution of permeability and relative permeability. Based…
View article: Aortobronchial Fistula: A Case Report and Literature Review
Aortobronchial Fistula: A Case Report and Literature Review Open
This report details the urgent management of a life‐threatening aortobronchial fistula (ABF) in a 61‐year‐old male with a history of esophageal cancer surgery, who presented with massive hemoptysis, underscoring the critical role of rapid …
View article: Postoperative kinesiophobia in elderly patients with femoral neck fractures: a prospective study of psychological and social determinants
Postoperative kinesiophobia in elderly patients with femoral neck fractures: a prospective study of psychological and social determinants Open
Objectives This study examined the psychosocial correlates of postoperative kinesiophobia in elderly patients with femoral neck fractures, with a focus on the roles of psychological resilience and social support in mitigating movement-rela…
View article: Correction: Effects of high-definition transcranial direct current stimulation for the treatment of chronic insomnia: a randomized, double-blind, controlled trial
Correction: Effects of high-definition transcranial direct current stimulation for the treatment of chronic insomnia: a randomized, double-blind, controlled trial Open
View article: Cultural Sustainability Through Heritage-Led Underground Development: The Case Study
Cultural Sustainability Through Heritage-Led Underground Development: The Case Study Open
The integration of cultural heritage into sustainable urban development has garnered increasing attention, with a growing recognition of its role in fostering resilient, inclusive, and identity-rich cities. While surface-level monuments of…
View article: Cellular angiofibroma of the inguinal scrotal region: A rare case report
Cellular angiofibroma of the inguinal scrotal region: A rare case report Open
Rationale: Cellular angiofibroma (CAF) is a rare benign mesenchymal tumor, which is difficult to diagnose due to its lack of specificity in clinical and imaging manifestations. This case highlights the challenges in the preoperative diagno…
View article: Cultural Soft Power Empowering Grassroots Political Mobilization
Cultural Soft Power Empowering Grassroots Political Mobilization Open
This paper aims to explore the dual effects of cultural soft power on empowering grassroots political mobilization. In the context of globalization, culture, as a core political resource, plays an increasingly prominent role in consolidati…
View article: A Fast and Lightweight Model for Causal Audio-Visual Speech Separation
A Fast and Lightweight Model for Causal Audio-Visual Speech Separation Open
Audio-visual speech separation (AVSS) aims to extract a target speech signal from a mixed signal by leveraging both auditory and visual (lip movement) cues. However, most existing AVSS methods exhibit complex architectures and rely on futu…
View article: Blood pressure levels and risk of intracerebral hemorrhage in the general population: evidence from a large prospective cohort study
Blood pressure levels and risk of intracerebral hemorrhage in the general population: evidence from a large prospective cohort study Open
In this large cohort of adults without baseline stroke and coronary heart disease, moderately lower BP levels were associated with reduced risk of incident ICH. These findings may help refine our understanding of BP thresholds relevant to …
View article: Unraveling the multidimensional association of covert bullying, abandonment, and adolescent depression: A critical review and conceptual framework
Unraveling the multidimensional association of covert bullying, abandonment, and adolescent depression: A critical review and conceptual framework Open
This critical review examines the complex relationships between covert bullying, feelings of abandonment, and adolescent depression through an integrative analysis of contemporary literature. By synthesizing evidence from empirical studies…
View article: Photodoping strategies in two‐dimensional semiconductors: Mechanisms, characterizations, and emerging applications
Photodoping strategies in two‐dimensional semiconductors: Mechanisms, characterizations, and emerging applications Open
The rapid expansion of two‐dimensional (2D) van der Waals semiconductors has enabled new possibilities for next‐generation electronic and optoelectronic technologies. However, the absence of robust, scalable, and CMOS‐compatible doping str…
View article: Current status and influencing factors of decision-making readiness among lung cancer patients during chemotherapy: a cross-sectional study based on CSM model
Current status and influencing factors of decision-making readiness among lung cancer patients during chemotherapy: a cross-sectional study based on CSM model Open
Objective This study aimed to investigate the current status of decision - making readiness (DMR) among lung cancer patients during chemotherapy and to explore its influencing factors, with the goal of informing targeted clinical intervent…
View article: Screening and verification of EmMYB5 in flavonoids biosynthesis in Elaeagnus mollis dies kernel
Screening and verification of EmMYB5 in flavonoids biosynthesis in Elaeagnus mollis dies kernel Open
Flavonoids are natural bioactive compounds with demonstrated health benefits in humans. Elaeagnus mollis Diels is a novel developing woody oil crop, and the flavonoids in E. mollis have attracted more attention. However, the composition co…
View article: APPLICATION OF <italic>BACILLUS SUBTILIS</italic> TO IMPROVE GROWTH, IMMUNITY, AND RESISTANCE TO <italic>VIBRIO PARAHAEMOLYTICUS</italic> INFECTION IN <italic>LITOPENAEUS VANNAMEI</italic>
APPLICATION OF <italic>BACILLUS SUBTILIS</italic> TO IMPROVE GROWTH, IMMUNITY, AND RESISTANCE TO <italic>VIBRIO PARAHAEMOLYTICUS</italic> INFECTION IN <italic>LITOPENAEUS VANNAMEI</italic> Open
View article: Atomic‐Level Dual‐Cation Engineering Enables High‐Performance Na<sub>4</sub>VMn(PO<sub>4</sub>)<sub>3</sub> Cathodes for Sodium‐Ion Batteries
Atomic‐Level Dual‐Cation Engineering Enables High‐Performance Na<sub>4</sub>VMn(PO<sub>4</sub>)<sub>3</sub> Cathodes for Sodium‐Ion Batteries Open
Na Super Ionic Conductor (NASICON)‐type Na 4 VMn(PO 4 ) 3 (NVMP) is a promising cathode for sodium‐ion batteries (SIBs) but suffers from sluggish Na‐ion transport and capacity fading. Here, we propose a site‐selective dual‐cation engineeri…
View article: Extrapulmonary metastases impact survival outcomes of thermal ablation for colorectal lung oligometastases: A multicenter study
Extrapulmonary metastases impact survival outcomes of thermal ablation for colorectal lung oligometastases: A multicenter study Open
BACKGROUND Colorectal cancer (CRC) frequently metastasizes to the lungs, and image-guided thermal ablation (IGTA) has emerged as a promising treatment for oligometastatic colorectal lung metastases (CRLM). However, high-quality multicenter…
View article: Spectral Sidebands Formed in Soliton Fiber Lasers
Spectral Sidebands Formed in Soliton Fiber Lasers Open
Spectral sideband formation is a fundamental phenomenon in soliton fiber lasers, arising from multiple mechanisms. The most recognized are Kelly sidebands, generated from the linear interference between a soliton and dispersive waves due t…
View article: Intracardiac vs Transesophageal Echocardiography in Atrial Fibrillation Ablation
Intracardiac vs Transesophageal Echocardiography in Atrial Fibrillation Ablation Open
Importance Transesophageal echocardiography (TEE) is the standard imaging modality for thrombus screening prior to atrial fibrillation (AF) ablation but carries procedural risks. Intracardiac echocardiography (ICE) is an alternative that m…
View article: Medication stewardship by clinical pharmacists in acute ischemic stroke care: a retrospective analysis of drug-related problem reduction and cost-saving outcomes
Medication stewardship by clinical pharmacists in acute ischemic stroke care: a retrospective analysis of drug-related problem reduction and cost-saving outcomes Open
Background In China’s evolving Diagnosis-Intervention Packet (DIP) payment system, suboptimal medication practices in acute ischemic stroke (AIS) care exacerbate healthcare costs and antimicrobial resistance. This study evaluates the clini…
View article: Information-theoretic multi-scale geometric pre-training for enhanced molecular property prediction
Information-theoretic multi-scale geometric pre-training for enhanced molecular property prediction Open
Maximizing information transfer across different structural scales is critical for effective molecular representation learning. Current molecular graph neural networks fail to fully capture the multi-scale nature of molecular geometry, lea…
View article: The Debate on RLVR Reasoning Capability Boundary: Shrinkage, Expansion, or Both? A Two-Stage Dynamic View
The Debate on RLVR Reasoning Capability Boundary: Shrinkage, Expansion, or Both? A Two-Stage Dynamic View Open
The ongoing debate on whether reinforcement learning with verifiable rewards (RLVR) expands or shrinks the reasoning capabilities of large language models (LLMs) remains unresolved. Some studies contend that RLVR mainly improves sampling e…
View article: Specific human antibodies against SARS-CoV-2 and monkeypox virus generated via a rapid construction and screening system
Specific human antibodies against SARS-CoV-2 and monkeypox virus generated via a rapid construction and screening system Open
View article: MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentation
MATCH: Multi-faceted Adaptive Topo-Consistency for Semi-Supervised Histopathology Segmentation Open
In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…
View article: A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma
A Tonic Signaling Code Predicts CAR-T Cell Efficacy in Diffuse Midline Glioma Open
Summary Diffuse midline glioma (DIPG/DMG) is a uniformly fatal pediatric brain tumor with no effective cure. Although CAR T-cell therapy shows promise, clinical outcomes remain inconsistent due to limited persistence and premature exhausti…
View article: Experimental analysis and quality optimization of honeycomb seal structures processed via grinding-assisted electrochemical discharge machining
Experimental analysis and quality optimization of honeycomb seal structures processed via grinding-assisted electrochemical discharge machining Open