Yuelei Jin
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View article: Effects of Nitric Oxide Expression on Hearing Loss
Effects of Nitric Oxide Expression on Hearing Loss Open
The role of nitric oxide (NO) in the onset and pathogenesis of hearing loss remains a matter of debate. To address this, we conducted a narrative review of the literature on the subject. We performed a literature search of SCOPUS, PubMed, …
View article: Association between B‑<i>Myb</i> proto‑oncogene and the development of malignant tumors (Review)
Association between B‑<i>Myb</i> proto‑oncogene and the development of malignant tumors (Review) Open
B-Myb is a critical transcription factor in regulating cell cycle. Dysregulated expression of B-Myb promotes tumor formation and development. B-Myb is a proto-oncogene ubiquitously expressed in proliferating cells, which maintains normal c…
View article: Role of homocysteine in the development and progression of Parkinson’s disease
Role of homocysteine in the development and progression of Parkinson’s disease Open
Homocysteine is an essential intermediate product of biochemical reactions that is present in various tissues of the human body. Homocysteine may be associated with the development and progression of Parkinson’s disease. Plasma homocystein…
View article: Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance via PTEN-mediated crosstalk between the PI3K/Akt and Erk/MAPKs signaling pathways in the skeletal muscles of db/db mice
Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance via PTEN-mediated crosstalk between the PI3K/Akt and Erk/MAPKs signaling pathways in the skeletal muscles of db/db mice Open
Background Globally, 1 in 11 adults have diabetes mellitus, and 90% of the cases are type 2 diabetes mellitus. Insulin resistance is a central defect in type 2 diabetes mellitus, and although multiple drugs have been developed to ameliorat…
View article: Gut Microbiota Dysbiosis Drives the Development of Colorectal Cancer
Gut Microbiota Dysbiosis Drives the Development of Colorectal Cancer Open
Background: The gut microbiota is a diverse community of microbes that maintain the stability of the intestinal environment. Dysbiosis of the gut microbiota has been linked to gastrointestinal diseases, such as colorectal cancer (CRC) – a …
View article: B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3
B-Myb Mediates Proliferation and Migration of Non-Small-Cell Lung Cancer via Suppressing IGFBP3 Open
B-Myb has been shown to play an important oncogenic role in several types of human cancers, including non-small-cell lung cancer (NSCLC). We previously found that B-Myb is aberrantly upregulated in NSCLC, and overexpression of B-Myb can si…
View article: B-Myb Is Up-Regulated and Promotes Cell Growth and Motility in Non-Small Cell Lung Cancer
B-Myb Is Up-Regulated and Promotes Cell Growth and Motility in Non-Small Cell Lung Cancer Open
B-Myb is a transcription factor that is overexpressed and plays an oncogenic role in several types of human cancers. However, its potential implication in lung cancer remains elusive. In the present study, we have for the first time invest…