Lili Dong
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View article: Central Toxic Keratopathy after Small Incision Lenticule：a case report
Central Toxic Keratopathy after Small Incision Lenticule：a case report Open
Objective To report a case of central toxic keratopathy (CTK) occurring after small incision lenticule extraction (SMILE) in a monocular patient, with an 18-month follow-up. Methods The patient’s postoperative condition was monitored throu…
View article: Study on the Motion Behavior of Charged Droplets near Plant Leaves
Study on the Motion Behavior of Charged Droplets near Plant Leaves Open
Conventional spraying often results in poor deposition on the abaxial (lower) leaf surface and within the middle-to-lower canopy, where pest and disease pressures are typically highest. In this study, we evaluated the performance of electr…
View article: METTL3 blocked the progression of diabetic retinopathy through m6A-modified SOX2
METTL3 blocked the progression of diabetic retinopathy through m6A-modified SOX2 Open
We aimed to explore the regulatory effects of methyltransferase-like 3 (METTL3) on diabetic retinopathy (DR) by regulating the m6A modification of SOX2 mRNA and elucidating the underlying molecular mechanism. The DR model was established b…
View article: Baicalin alleviates the injury of human retinal pigment epithelium cells and improves branch retinal vein occlusion in rats by inhibiting the HIF-1α/VEGFA axis
Baicalin alleviates the injury of human retinal pigment epithelium cells and improves branch retinal vein occlusion in rats by inhibiting the HIF-1α/VEGFA axis Open
View article: Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review)
Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review) Open
Pancreatic ductal adenocarcinoma (PDAC) is a malignant neoplasm that typically manifests with subtle clinical manifestations in its early stages and frequently eludes diagnosis until the advanced phases of the disease. The limited therapeu…
View article: The intervention effect of psychological care combined with ondansetron, dexamethasone, and promethazine hydrochloride on chemotherapy in breast cancer surgical patients
The intervention effect of psychological care combined with ondansetron, dexamethasone, and promethazine hydrochloride on chemotherapy in breast cancer surgical patients Open
BACKGROUND: Breast cancer (BC) is one of the most common malignancies in women and imposes a significant health burden globally. According to data from the World Health Organization, the incidence of BC has been increasing steadily over th…
View article: Feasibility validation of automatic diagnosis of mitral valve prolapse from multi-view echocardiographic sequences based on deep neural network
Feasibility validation of automatic diagnosis of mitral valve prolapse from multi-view echocardiographic sequences based on deep neural network Open
Aims To address the limitations of traditional diagnostic methods for mitral valve prolapse (MVP), specifically fibroelastic deficiency (FED) and Barlow’s disease (BD), by introducing an automated diagnostic approach utilizing multi-view e…
View article: CardiacField: computational echocardiography for automated heart function estimation using two-dimensional echocardiography probes
CardiacField: computational echocardiography for automated heart function estimation using two-dimensional echocardiography probes Open
Aims Accurate heart function estimation is vital for detecting and monitoring cardiovascular diseases. While two-dimensional echocardiography (2DE) is widely accessible and used, it requires specialized training, is prone to inter-observer…
View article: Response and disease resistance evaluation of sorghum seedlings under anthracnose stress
Response and disease resistance evaluation of sorghum seedlings under anthracnose stress Open
View article: A Coronary-Friendly Device Mitigating Risk of Coronary Obstruction in Transcatheter Aortic Valve Replacement
A Coronary-Friendly Device Mitigating Risk of Coronary Obstruction in Transcatheter Aortic Valve Replacement Open
Stand-alone TAVR using the J-Valve may mitigate the risk of TAVR-induced CAO.
View article: Association of Mitral Valve Geometry at CT with Secondary Mitral Regurgitation after Transcatheter Aortic Valve Replacement in Patients with Aortic Regurgitation
Association of Mitral Valve Geometry at CT with Secondary Mitral Regurgitation after Transcatheter Aortic Valve Replacement in Patients with Aortic Regurgitation Open
Background: The improvement rate and predictors of secondary mitral regurgitation in patients with aortic regurgitation undergoing transcatheter aortic valve replacement (TAVR) remain unclear. This study aimed to identify predictors of per…
View article: Pro-angiogenic cytokine features of left ventricular remodeling in patients with bicuspid aortic valve
Pro-angiogenic cytokine features of left ventricular remodeling in patients with bicuspid aortic valve Open
Decreased angiogenesis plays a crucial role in the occurrence and progression of LVR in patients with BAV. Disturbance in the pro- and anti-angiogenesis equilibrium in BAV patients with LVR may reflect the aggravation of endothelial injury…
View article: Feasibility Study of a Novel Transapical Chordal Implantation System in a Porcine Model
Feasibility Study of a Novel Transapical Chordal Implantation System in a Porcine Model Open
Transapical beating-heart mitral repair with chordal implantation system has been considered as an alternative treatment for degenerative mitral regurgitation. This study aimed to assess the feasibility and safety of the E-Chord system (Me…
View article: In vitro and clinical validation of different correction algorithms for the two-dimensional proximal isovelocity surface area method in a low-velocity flow field for quantifying tricuspid regurgitation
In vitro and clinical validation of different correction algorithms for the two-dimensional proximal isovelocity surface area method in a low-velocity flow field for quantifying tricuspid regurgitation Open
Using a correction factor of 0.7 in quantifying TR provides similar accuracy when compared to other techniques. This represents a valuable clinical tool for quickly correcting the underestimation of the 2D PISA method in TR. This simple me…
View article: M-mode proximal iso-velocity surface area-based dynamics of instantaneous flow rate and its implications for degenerative mitral regurgitation quantification
M-mode proximal iso-velocity surface area-based dynamics of instantaneous flow rate and its implications for degenerative mitral regurgitation quantification Open
Background Instantaneous flow rate of degenerative mitral regurgitation (DMR) showed dynamic changes. However, inconsistencies exist across literatures about the timing of measurements for flow convergence in proximal iso-velocity surface …
View article: Relative size of the effective regurgitant orifice to right ventricular cavity contributes significantly to the underestimation of 2D PISA method in tricuspid regurgitation quantitation
Relative size of the effective regurgitant orifice to right ventricular cavity contributes significantly to the underestimation of 2D PISA method in tricuspid regurgitation quantitation Open
Background 2D proximal isovelocity surface area (PISA) method underestimates tricuspid regurgitation (TR) severity largely due to the distortion of proximal flow geometry under low jet velocity. Previous studies demonstrated that the confi…
View article: Continuous 3D Myocardial Motion Tracking via Echocardiography
Continuous 3D Myocardial Motion Tracking via Echocardiography Open
Myocardial motion tracking stands as an essential clinical tool in the prevention and detection of cardiovascular diseases (CVDs), the foremost cause of death globally. However, current techniques suffer from incomplete and inaccurate moti…
View article: Association of mitral valve geometry at CT with secondary mitral regurgitation after transcatheter aortic valve replacement in patients with aortic regurgitation
Association of mitral valve geometry at CT with secondary mitral regurgitation after transcatheter aortic valve replacement in patients with aortic regurgitation Open
Purpose To determine predictors of persistent moderate to severe secondary mitral regurgitation in patients with aortic regurgitation after transcatheter aortic valve replacement (TAVR) by mitral valve geometry assessment at CT. Methods Th…
View article: Echocardiographic parameters recommended for assessing the severity of tricuspid regurgitation: concordance and discordance
Echocardiographic parameters recommended for assessing the severity of tricuspid regurgitation: concordance and discordance Open
Concordance seems limited when using echocardiographic parameters to assess TR severity. Applying only EROA, RVol, and VCW results in better concordance, as recommended by the current guidelines.
View article: CardiacField: Computational Echocardiography for Universal Screening
CardiacField: Computational Echocardiography for Universal Screening Open
Cardiovascular diseases, the worldwide leading cause of death, are preventable and treatable. Early diagnosis and monitoring using ultrasound, x-ray or MRI are crucial clinical tools. Routine imaging is, however, currently cost prohibitive…
View article: Echocardiographic myocardial work in pre-adolescent male basketball players: a comparison with cardiopulmonary exercise test-derived aerobic capacity
Echocardiographic myocardial work in pre-adolescent male basketball players: a comparison with cardiopulmonary exercise test-derived aerobic capacity Open
Background: Pressure-strain loop (PSL) analysis provides a novel, less load-dependent non-invasive method to quantify myocardial work and demonstrates a significant correlation with the contractile reserve in adult athletes. We aim to vali…
View article: Short-Term Outcomes After Transcatheter Aortic Valve Replacement in Predominant Aortic Regurgitation with Left Ventricular Dysfunction
Short-Term Outcomes After Transcatheter Aortic Valve Replacement in Predominant Aortic Regurgitation with Left Ventricular Dysfunction Open
Patients with aortic stenosis and low left ventricular ejection fraction (LVEF) would benefit from transcatheter aortic valve replacement. However, the safety and efficacy of transcatheter aortic valve replacement in patients with aortic r…
View article: Transcatheter Mitral Valve-in-Valve Implantation With a New Transcatheter Heart Valve for Bioprosthetic Degeneration
Transcatheter Mitral Valve-in-Valve Implantation With a New Transcatheter Heart Valve for Bioprosthetic Degeneration Open
Background Transcatheter mitral valve-in-valve (TMVIV) procedure with aortic transcatheter heart valves has recently become a less invasive alternative for patients with mitral bioprosthetic dysfunction. This study reports the initial expe…
View article: Knockdown of KCNQ1OT1 Alleviates the Activation of NLRP3 Inflammasome Through miR-17-5p/TXNIP Axis in Retinal Müller Cells
Knockdown of KCNQ1OT1 Alleviates the Activation of NLRP3 Inflammasome Through miR-17-5p/TXNIP Axis in Retinal Müller Cells Open
Diabetic retinopathy (DR) is one of the most severe and common complications caused by diabetic mellites. Inhibiting NLRP3 inflammasome activation displays a crucial therapeutic value in DR. Studies have shown that KCNQ1OT1 plays a critica…
View article: Clinical Performance of a Powered Surgical Stapler for Left Atrial Appendage Resection in a Video-Assisted Thoracoscopic Ablation for Patients with Nonvalvular Atrial Fibrillation
Clinical Performance of a Powered Surgical Stapler for Left Atrial Appendage Resection in a Video-Assisted Thoracoscopic Ablation for Patients with Nonvalvular Atrial Fibrillation Open
Left atrial appendage (LAA) has been found to be associated with the occurrence of thromboembolism in patients with nonvalvular atrial fibrillation (NVAF). Stapling exclusion of LAA during surgical ablation could be an alternative to oral …
View article: Current status of comprehensive metabolic control and predictive model of blood glucose control in low-income patients with type 2 diabetes
Current status of comprehensive metabolic control and predictive model of blood glucose control in low-income patients with type 2 diabetes Open
Objective: The purpose of this study was to comprehensively evaluate and explore the current situation of comprehensive metabolic control, the factors that influence glycemic control and the relationships among these factors in patients wi…
View article: Trendelenburg maneuver predicts fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation
Trendelenburg maneuver predicts fluid responsiveness in patients on veno-arterial extracorporeal membrane oxygenation Open
View article: Three-dimensional transthoracic echocardiographic evaluation of tricuspid regurgitation severity using proximal isovelocity surface area: comparison with volumetric method
Three-dimensional transthoracic echocardiographic evaluation of tricuspid regurgitation severity using proximal isovelocity surface area: comparison with volumetric method Open
View article: Mechanisms, features, and significance of diastolic mitral regurgitation: a case series
Mechanisms, features, and significance of diastolic mitral regurgitation: a case series Open
Background Diastolic mitral regurgitation (DMR) is a type of functional mitral regurgitation. Its occurrence in the diastolic phase of cardiac cycle renders DMR an easily ignored entity. Confusing it with systolic mitral regurgitation occa…
View article: Three-dimensional Transthoracic Echocardiographic Evaluation of Tricuspid Regurgitation Severity Using Proximal Isovelocity Surface Area: Comparison With Volumetric Method
Three-dimensional Transthoracic Echocardiographic Evaluation of Tricuspid Regurgitation Severity Using Proximal Isovelocity Surface Area: Comparison With Volumetric Method Open
Background The quantification of tricuspid regurgitation(TR) using three-dimensional(3D) proximal isovelocity surface area (PISA)derived effective regurgitant orifice area (EROA) is feasible in functional TR. The aim of our study was to ex…