Yueshuang Lu
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View article: Antagonistic regulation of LINE-1/Alu elements and their repressor APOBEC3B in cellular senescence
Antagonistic regulation of LINE-1/Alu elements and their repressor APOBEC3B in cellular senescence Open
Long Interspersed Nuclear Elements-1 (LINE-1 or L1) make up approximately 21% of the human genome, with some L1 loci containing intact open reading frames (ORFs) that facilitate retrotransposition. Because retrotransposition can have delet…
View article: Inhibition of placental trophoblast fusion by guanylate-binding protein 5
Inhibition of placental trophoblast fusion by guanylate-binding protein 5 Open
Syncytin-1 and Syncytin-2 are envelope glycoproteins encoded by human endogenous retroviruses that have been exapted for the fusion of cytotrophoblast cells into syncytiotrophoblasts during placental development. Pregnancy complications li…
View article: Viral influencers: deciphering the role of endogenous retroviral LTR12 repeats in cellular gene expression
Viral influencers: deciphering the role of endogenous retroviral LTR12 repeats in cellular gene expression Open
The human genome is like a museum of ancient retroviral infections. It contains a large number of endogenous retroviruses (ERVs) that bear witness to past integration events. About 5,000 of them are so-called long terminal repeat 12 (LTR12…
View article: An Arabidopsis root phloem pole cell atlas reveals <i>PINEAPPLE</i> genes as transitioners to autotrophy
An Arabidopsis root phloem pole cell atlas reveals <i>PINEAPPLE</i> genes as transitioners to autotrophy Open
Single cell sequencing has recently allowed the generation of exhaustive root cell atlases. However, some cell types are elusive and remain underrepresented. Here, we use a second- generation single cell approach, where we zoom in on the r…