Yi Zhang
YOU?
Author Swipe
View article: Procalcitonin-Guided Antibiotic Therapy in Adult Sepsis: A Biochemical Perspective from a Retrospective Cohort Study
Procalcitonin-Guided Antibiotic Therapy in Adult Sepsis: A Biochemical Perspective from a Retrospective Cohort Study Open
Background: Procalcitonin (PCT), a biomarker closely associated with bacterial infections, has emerged as a valuable tool in guiding antibiotic therapy. In sepsis management, it may help optimize antibiotic use and improve clinical outcome…
View article: Effectiveness of dual-site transcranial magnetic stimulation on motor function and activities of daily living in stroke patients: a systematic review and meta-analysis of randomized controlled trials
Effectiveness of dual-site transcranial magnetic stimulation on motor function and activities of daily living in stroke patients: a systematic review and meta-analysis of randomized controlled trials Open
Background Dual-site transcranial magnetic stimulation (TMS) has emerged as a promising neuromodulation technique in stroke rehabilitation. By targeting multiple brain regions, dual-site TMS may enhance neuroplasticity more effectively tha…
View article: CONFETTI: Conversational Function-Calling Evaluation Through Turn-Level Interactions
CONFETTI: Conversational Function-Calling Evaluation Through Turn-Level Interactions Open
We introduce Conversational Function-Calling Evaluation Through Turn-Level Interactions (CONFETTI), a conversational benchmark1 designed to evaluate the function-calling capabilities and response quality of large language models (LLMs). Cu…
View article: Fe<sup>3+</sup>/Yb<sup>3+</sup> Co‐Activated MgGa<sub>2</sub>O<sub>4</sub> Phosphor as Widely Near‐Infrared Lighting for Night‐Vision, Non‐Destructive Imaging, and Plant Cultivation
Fe<sup>3+</sup>/Yb<sup>3+</sup> Co‐Activated MgGa<sub>2</sub>O<sub>4</sub> Phosphor as Widely Near‐Infrared Lighting for Night‐Vision, Non‐Destructive Imaging, and Plant Cultivation Open
Fe 3+ as an activator for Near‐infrared (NIR) phosphors has the advantages over Cr 3+ and Ni 2+ due to its abundant resource, low cost, nontoxic, and eco‐friendly features, making it a luminescence activator candidate with huge commercial …
View article: HIF-1α/LTBP2 axis activate HSCs to promote liver fibrosis by interacting with LOXL1 via the ERK pathway
HIF-1α/LTBP2 axis activate HSCs to promote liver fibrosis by interacting with LOXL1 via the ERK pathway Open
View article: Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction
Enhanced or reversible RNA N6-methyladenosine editing by red/far-red light induction Open
The RNA N6-methyladenosine (m6A) modification is a critical regulator of various biological processes, but precise and dynamic control of m6A remains a challenge. In this work, we present a red/far-red light-inducible m6A editing system th…
View article: CONFETTI: Conversational Function-Calling Evaluation Through Turn-Level Interactions
CONFETTI: Conversational Function-Calling Evaluation Through Turn-Level Interactions Open
View article: Integrated analyses and a novel nomogram for the prediction of significant fibrosis in patients
Integrated analyses and a novel nomogram for the prediction of significant fibrosis in patients Open
LTBP2 may be a new biomarker for liver fibrosis patients. The nomogram showed better diagnostic performance in patients.
View article: Multifunctional Near-Infrared Luminescence Performance of Nd3+ Doped SrSnO3 Phosphor
Multifunctional Near-Infrared Luminescence Performance of Nd3+ Doped SrSnO3 Phosphor Open
The phosphors with persistent luminescence in the NIR (near-infrared) region and the NIR-to-NIR Stokes luminescence properties have received considerable attention owing to their inclusive application prospects in the in vivo imaging field…
View article: Distributed cooperative guidance strategy based on virtual negotiation and rolling optimization
Distributed cooperative guidance strategy based on virtual negotiation and rolling optimization Open
The problem of multi-UAV cooperative guidance under target maneuvering conditions is studied, and a distributed cooperative guidance strategy based on virtual negotiation mechanism and rolling horizon optimization is proposed. Firstly, in …
View article: Identifying modifiable factors associated with neuroimaging markers of brain health
Identifying modifiable factors associated with neuroimaging markers of brain health Open
Aims Brain structural alterations begin long before the presentation of brain disorders; therefore, we aimed to systematically investigate a wide range of influencing factors on neuroimaging markers of brain health. Methods Utilizing data …
View article: Cerebellar transcranial magnetic stimulation for improving balance capacity and activity of daily living in stroke patients: a systematic review and meta-analysis
Cerebellar transcranial magnetic stimulation for improving balance capacity and activity of daily living in stroke patients: a systematic review and meta-analysis Open
View article: Factors associated with immune-related thyroid dysfunction induced by PD-1/PD-L1 inhibitors in cancer patients: an observational study
Factors associated with immune-related thyroid dysfunction induced by PD-1/PD-L1 inhibitors in cancer patients: an observational study Open
This study aimed to identify the potential factors associated with immune thyroid dysfunction caused by programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) inhibitors in cancer patients. We conducted a retrospective study of thyroi…
View article: Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis
Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis Open
Background The synthetic liver X receptor ligand (LXR) T0901317 (T0) has been reported to attenuate atherosclerosis (AS) without hyperglyceridemia due to innovative drug combination or nano-sized drug delivery. Given the key roles of mangi…
View article: A Bayesian disease progression model for Major Depressive Disorder
A Bayesian disease progression model for Major Depressive Disorder Open
View article: Memory Box: Exploring the Potential of VR in Memory and Loneliness Healing
Memory Box: Exploring the Potential of VR in Memory and Loneliness Healing Open
View article: High SNHG expression may predict a poor lung cancer prognosis based on a meta-analysis
High SNHG expression may predict a poor lung cancer prognosis based on a meta-analysis Open
Background An increasing number of small nucleolar RNA host genes (SNHGs) have been revealed to be dysregulated in lung cancer tissues, and abnormal expression of SNHGs is significantly correlated with the prognosis of lung cancer. The pur…
View article: Construction and validation of a novel IGFBP3-related signature to predict prognosis and therapeutic decision making for Hepatocellular Carcinoma
Construction and validation of a novel IGFBP3-related signature to predict prognosis and therapeutic decision making for Hepatocellular Carcinoma Open
Background IGFBP3 plays a pivotal role in carcinogenesis by being anomalously expressed in some malignancies. However, the clinical value of IGFBP3 and the role of IGFBP3-related signature in HCC remain unclear. Methods Multiple bioinforma…
View article: Identification of pyroptosis-related long non-coding RNAs with prognosis and therapy in lung squamous cell carcinoma
Identification of pyroptosis-related long non-coding RNAs with prognosis and therapy in lung squamous cell carcinoma Open
View article: Hepatitis B Virus X Protein Is Stabilized by the Deubiquitinating Enzyme VCPIP1 in a Ubiquitin-Independent Manner by Recruiting the 26S Proteasome Subunit PSMC3
Hepatitis B Virus X Protein Is Stabilized by the Deubiquitinating Enzyme VCPIP1 in a Ubiquitin-Independent Manner by Recruiting the 26S Proteasome Subunit PSMC3 Open
HBx is a multifunctional viral oncoprotein that plays an essential role in the viral life cycle and hepatocarcinogenesis. HBx degradation occurs through the ubiquitin-proteasome system (UPS).
View article: Microglia polarization in heat-induced early neural injury
Microglia polarization in heat-induced early neural injury Open
Introduction In the occurrence and development of heat stroke (HS), factors such as hyperthermia, ischemia and hypoxia are essential to the central nervous system (CNS) inflammatory response, but the main mechanism underlying CNS inflammat…
View article: Epidemiology and association rules analysis for pulmonary tuberculosis cases with extrapulmonary tuberculosis from age and gender perspective: a large-scale multi-center observational study in China
Epidemiology and association rules analysis for pulmonary tuberculosis cases with extrapulmonary tuberculosis from age and gender perspective: a large-scale multi-center observational study in China Open
Background Tuberculosis (TB), a multi-systemic disease with protean presentation, remains a major global health problem. Although concurrent pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) cases are commonly observed cl…
View article: Effect of PDCA-based nursing intervention on activities of daily living, neurological function and self-management in acute cerebral stroke.
Effect of PDCA-based nursing intervention on activities of daily living, neurological function and self-management in acute cerebral stroke. Open
PDCA-based nursing intervention can substantially enhance the daily living ability, neurological function, and self-management ability of patients, thus contributing to improve the clinical prognosis of patients and as such is worth popula…
View article: The Human Brain Is Best Described as Being on a Female/Male Continuum: Evidence from a Neuroimaging Connectivity Study
The Human Brain Is Best Described as Being on a Female/Male Continuum: Evidence from a Neuroimaging Connectivity Study Open
Psychological androgyny has long been associated with greater cognitive flexibility, adaptive behavior, and better mental health, but whether a similar concept can be defined using neural features remains unknown. Using the neuroimaging da…
View article: Small hepatitis B virus surface antigen promotes malignant progression of hepatocellular carcinoma via endoplasmic reticulum stress-induced FGF19/JAK2/STAT3 signaling
Small hepatitis B virus surface antigen promotes malignant progression of hepatocellular carcinoma via endoplasmic reticulum stress-induced FGF19/JAK2/STAT3 signaling Open
Chronic hepatitis B virus (HBV) infection is one of the major global health problems. Although the small protein of hepatitis B virus surface antigen (HBsAg), SHBs, is the most abundant HBV viral protein, its pathogenic role and molecular …
View article: Effect of Circhipk3 on Polarization of Microglial Cells in Nerve Injury Caused by Heat Radiation
Effect of Circhipk3 on Polarization of Microglial Cells in Nerve Injury Caused by Heat Radiation Open
Background: Circular RNAs play an important regulatory role in the occurrence and development of nerve damage and related diseases, but there is little research on non-coding RNAs in heat sickness, especially circRNAs, and there has been n…
View article: Regulation effects of total flavonoids in Morus alba L. on hepatic cholesterol disorders in orotic acid induced NAFLD rats
Regulation effects of total flavonoids in Morus alba L. on hepatic cholesterol disorders in orotic acid induced NAFLD rats Open
Background Mulberry leaves are the dried leaves of Morus alba L., flavonoids from mulberry leaves (MLF) has showed regulatory effect on abnormal lipid metabolism, but the regulatory mechanism of MLF on cholesterol metabolism is still missi…
View article: Nuciferine prevents hepatic steatosis by regulating lipid metabolismin diabetic rat model
Nuciferine prevents hepatic steatosis by regulating lipid metabolismin diabetic rat model Open
Objective This study investigatesthe nuciferine capacity to regulate the liver’s lipid metabolism regarding steatosis and injury in STZ-induced diabetic rats. Materials and Methods The rats were randomly divided into groups control, diabet…
View article: Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model
Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model Open
Previous postmortem and animal studies have shown decreases in the prefrontal cortex (PFC) volume and the number of glial cells in the PFC of depression. Running exercise has been shown to alleviate depressive symptoms. However, the effect…
View article: MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling
MiR-27a promotes insulin resistance and mediates glucose metabolism by targeting PPAR-γ-mediated PI3K/AKT signaling Open
This study aimed to establish a high-fat diet (HFD)-fed obese mouse model and a cell culture model of insulin resistance (IR) in mature 3T3-L1 adipocytes. A dual-luciferase reporter assay (DLRA) was confirmed interaction between miR-27a an…