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View article: Cognitive Enhancement in PSCI: a Retrospective Study on rTMS and HBO therapy
Cognitive Enhancement in PSCI: a Retrospective Study on rTMS and HBO therapy Open
Post-stroke cognitive impairment (PSCI) severely impacts quality of life. Though repetitive transcranial magnetic stimulation (rTMS) and hyperbaric oxygen (HBO) have been researched for PSCI, their combined efficacy remains understudied. T…
View article: Full-length transcriptome analysis of papillary thyroid carcinoma reveals correlation between LAMB3 expression and clinical features
Full-length transcriptome analysis of papillary thyroid carcinoma reveals correlation between LAMB3 expression and clinical features Open
Background Thyroid carcinoma is the most common malignant endocrine tumour, and its prevalence has been on the rise in recent years. However, mechanisms underlying the metastasis of thyroid carcinoma and candidate biomarkers remain elusive…
View article: Scalable and deterministic construction of moiré superlattice in 2D materials using stressor films
Scalable and deterministic construction of moiré superlattice in 2D materials using stressor films Open
Moiré superlattice in two-dimensional (2D) materials provides a powerful platform to engineer emergent electronic states, yet the construction of moiré superlattices remains lab-scale, involving much trial and error and with little control…
View article: Identification of Risk Factors for Relapse following Rituximab Therapy in Children with Steroid-Sensitive Nephrotic Syndrome
Identification of Risk Factors for Relapse following Rituximab Therapy in Children with Steroid-Sensitive Nephrotic Syndrome Open
Introduction: Rituximab (RTX) is a key therapeutic agent for maintaining remission in steroid-dependent nephrotic syndrome and frequently relapsing nephrotic syndrome, demonstrating both efficacy and safety. However, reliable biomarkers fo…
View article: RFA-YOLOv8: A Robust Tea Bud Detection Model with Adaptive Illumination Enhancement for Complex Orchard Environments
RFA-YOLOv8: A Robust Tea Bud Detection Model with Adaptive Illumination Enhancement for Complex Orchard Environments Open
Accurate detection of tea shoots in natural environments is crucial for facilitating intelligent tea picking, field management, and automated harvesting. However, the detection performance of existing methods in complex scenes remains limi…
View article: The Distinction of Chemical Profiles of Mountainous Forest Cultivated Ginseng and Garden Ginseng Based on Calcium Oxalate Crystals, Organic Acids, and Ginsenosides
The Distinction of Chemical Profiles of Mountainous Forest Cultivated Ginseng and Garden Ginseng Based on Calcium Oxalate Crystals, Organic Acids, and Ginsenosides Open
This study aims to further analyze the chemical characteristics of mountainous forest cultivated ginseng (MFCG) and garden ginseng (GG), concerning their calcium oxalate crystals, organic acids, and ginsenosides. The results demonstrate th…
View article: Research Progress and Development Trend of Visual Detection Methods for Selective Fruit Harvesting Robots
Research Progress and Development Trend of Visual Detection Methods for Selective Fruit Harvesting Robots Open
The rapid development of artificial intelligence technologies has promoted the emergence of Agriculture 4.0, where the machines participating in agricultural activities are made smart with the capacities of self-sensing, self-decision-maki…
View article: Pseudohypoxia-Stabilized HIF2α Transcriptionally Inhibits MNRR1, a Druggable Target in MELAS
Pseudohypoxia-Stabilized HIF2α Transcriptionally Inhibits MNRR1, a Druggable Target in MELAS Open
The mitochondrial regulator MNRR1 is reduced in several pathologies, including the mitochondrial heteroplasmic disease MELAS, and genetic restoration of its level normalizes the pathological phenotype. Here, we investigate the upstream mec…
View article: OPENXRD: A Comprehensive Benchmark and Enhancement Framework for LLM/MLLM XRD Question Answering
OPENXRD: A Comprehensive Benchmark and Enhancement Framework for LLM/MLLM XRD Question Answering Open
This work presents OPENXRD, an open-book pipeline designed for crystallography question answering, which integrates textual prompts with concise supporting content generated by GPT-4.5. Instead of using scanned textbooks, which may lead to…
View article: Pan-Mitochondrial Genomic Analysis of Ginseng (Panax ginseng) Reveals Structural Variation, Phylogenetic Relationships, and Genetic Diversity
Pan-Mitochondrial Genomic Analysis of Ginseng (Panax ginseng) Reveals Structural Variation, Phylogenetic Relationships, and Genetic Diversity Open
Ginseng (Panax ginseng), a vital medicinal plant, faces challenges in genetic stability and directed breeding. This study aimed to elucidate mitochondrial genome structure, evolution, and phylogenetic relationships to guide germplasm conse…
View article: Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation
Serine/threonine/tyrosine kinase 1 drives pancreatic carcinogenesis via GSK3β sequestration-mediated Wnt/β-catenin pathway hyperactivation Open
View article: The role of MYEOV gene: a review and future directions
The role of MYEOV gene: a review and future directions Open
The overexpressed gene MYEOV in multiple myeloma, as an oncogene, has been widely recognized for its high expression levels in various malignant tumors. MYEOV plays a significant role in multiple malignancies, particularly in diseases such…
View article: YOLOv8-TEA: Recognition Method of Tender Shoots of Tea Based on Instance Segmentation Algorithm
YOLOv8-TEA: Recognition Method of Tender Shoots of Tea Based on Instance Segmentation Algorithm Open
With the continuous development of artificial intelligence technology, the transformation of traditional agriculture into intelligent agriculture is quickly accelerating. However, due to the diverse growth postures of tender shoots and com…
View article: Identification of Risk Factors for Relapse Following Rituximab Therapy in Children with Steroid-Sensitive Nephrotic Syndrome
Identification of Risk Factors for Relapse Following Rituximab Therapy in Children with Steroid-Sensitive Nephrotic Syndrome Open
Background Rituximab (RTX) is a key therapeutic agent for maintaining remission in steroid-dependent nephrotic syndrome (SDNS) and frequently relapsing nephrotic syndrome (FRNS), demonstrating both efficacy and safety. However, relapse ris…
View article: Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review)
Multiple roles of S100P in pan carcinoma: Biological functions and mechanisms (Review) Open
This article examines the multifaceted roles of the S100P gene in pan‑cancer, with the aim of exploring its biological functions and related mechanisms in depth. S100P is a small calcium‑binding protein that recent studies have identified …
View article: Targeting mixed lineage kinase domain-like protein's non-necroptosis role: A new horizon in anti-inflammatory therapy for alcoholic liver disease
Targeting mixed lineage kinase domain-like protein's non-necroptosis role: A new horizon in anti-inflammatory therapy for alcoholic liver disease Open
Although mixed lineage kinase domain-like protein (MLKL) is widely recognized as a critical effector in the necroptotic signaling pathway, MLKL plays broader regulatory roles beyond programmed necroptosis. Notably, Xuan Yuan et al demonstr…
View article: Association of middle cerebral artery aneurysms and variation of the A1 segment
Association of middle cerebral artery aneurysms and variation of the A1 segment Open
Objective The disturbance of blood flow caused by variations in the circle of Willis is an important factor in the occurrence and development of aneurysms. Previous studies have confirmed that a fetal-type posterior cerebral artery(PCA) is…
View article: Screening and Application of DNA Markers for Novel Quality Consistency Evaluation in Panax ginseng
Screening and Application of DNA Markers for Novel Quality Consistency Evaluation in Panax ginseng Open
Quality control remains a challenge in traditional Chinese medicine (TCM). This study introduced a novel genetic-based quality control method for TCM. Genetic variations in ginseng were evaluated across whole-genome, chloroplast genome, an…
View article: Granulomatous Lobular Mastitis: A Rare Case of Erythema Nodosum
Granulomatous Lobular Mastitis: A Rare Case of Erythema Nodosum Open
View article: Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury
Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury Open
View article: Long-term impact of COVID-19-related nonpharmaceutical interventions on tuberculosis: an interrupted time series analysis using Bayesian method
Long-term impact of COVID-19-related nonpharmaceutical interventions on tuberculosis: an interrupted time series analysis using Bayesian method Open
COVID-19 has had medium- and long-term impacts on TB epidemics, while the overall trend of TB incidence in Henan is generally declining. The BSTS model can be an effective option for accurately predicting the epidemic patterns of TB, and i…
View article: Differentiation of Mountainous Forest Cultivated Ginseng and Garden Ginseng Through the Calcium Oxalate Crystals, Oxalic Acid, and Other Organic Acids
Differentiation of Mountainous Forest Cultivated Ginseng and Garden Ginseng Through the Calcium Oxalate Crystals, Oxalic Acid, and Other Organic Acids Open
View article: Seeing the Unseen: A Cross-Domain Enhancement Framework with Prior-Guided Fusion for Subtle Chip-Surface Defect Detection
Seeing the Unseen: A Cross-Domain Enhancement Framework with Prior-Guided Fusion for Subtle Chip-Surface Defect Detection Open
View article: Sliding ferroelectric memories and synapses based on rhombohedral-stacked bilayer MoS2
Sliding ferroelectric memories and synapses based on rhombohedral-stacked bilayer MoS2 Open
Recent advances have uncovered an exotic sliding ferroelectric mechanism, which endows to design atomically thin ferroelectrics from non-ferroelectric parent monolayers. Although notable progress has been witnessed in understanding the fun…
View article: Polyketides and alkaloids from the fungus Aspergillus Fumigatus YB4-17 and ent-Fumiquinazoline J induce apoptosis, paraptosis in human hepatoma HepG2 cells
Polyketides and alkaloids from the fungus Aspergillus Fumigatus YB4-17 and ent-Fumiquinazoline J induce apoptosis, paraptosis in human hepatoma HepG2 cells Open
Hepatocellular carcinoma (HCC) is one of the most common malignancies. The currently available clinical drugs for HCC frequently cause serious side effects and the treatment outcomes are unsatisfactory. It is urgent to develop effective dr…
View article: A Visualized Bibliometric Analysis of Translation Studies of Mo Yan’s Works Using VOSviewer from 2000 to 2024
A Visualized Bibliometric Analysis of Translation Studies of Mo Yan’s Works Using VOSviewer from 2000 to 2024 Open
Mo Yan’s works hold a significant position in the global literary field, and the study of the translations of these works is considered a key approach to promoting literary cross-cultural communication and academic discussions in translati…
View article: Identification of regulatory network and potential drugs in spinal cord injury based on comprehensive bioinformatics analysis
Identification of regulatory network and potential drugs in spinal cord injury based on comprehensive bioinformatics analysis Open
Spinal cord injury (SCI) is a significant neurological disorder that results in permanent impairment of motor and sensory functions below the injury site. Oligodendrocytes and oligodendrocyte precursor cells (ODC/OPC) play a crucial role i…
View article: Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review
Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review Open
Marine fungi represent a treasure trove of bioactive secondary metabolites, with benzopyran compounds emerging as a significant class of these natural products. This review delves into the structural diversity, biological activities, and s…
View article: Pseudohypoxia-stabilized HIF2⍺ transcriptionally inhibits MNRR1, a druggable target in MELAS
Pseudohypoxia-stabilized HIF2⍺ transcriptionally inhibits MNRR1, a druggable target in MELAS Open
The observation that amounts of the mitochondrial regulator MNRR1 (CHCHD2, AAG10, PARK22) are reduced in several pathologies, and that restoration of its level normalizes the pathological phenotype, prompted a search for compounds that cou…
View article: Epidermolysis Bullosa Pruriginosa treated with baricitinib: A case report
Epidermolysis Bullosa Pruriginosa treated with baricitinib: A case report Open
Introduction: Epidermolysis Bullosa Pruriginosa (EBP) is a persistent, recurring disease that seriously affects quality of life. Fewer than 100 cases of EBP have been reported to date. Numerous inflammatory dermatoses are driven by soluble…