Yuko Kimura
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View article: Vaseline Coating on Paw Soles Alters the Spontaneous Gait of Rats
Vaseline Coating on Paw Soles Alters the Spontaneous Gait of Rats Open
Spontaneous walking behavior is modulated by various factors, but it remains almost unknown whether and how moisturizing paw soles of rats alters their gait. To this end, we allowed rats to spontaneously walk on a disk-shaped treadmill bef…
View article: Hepatocellular carcinoma with gastric adenocarcinoma treated with atezolizumab and bevacizumab
Hepatocellular carcinoma with gastric adenocarcinoma treated with atezolizumab and bevacizumab Open
Key Clinical Message Atezolizumab and bevacizumab combination therapy might be one of the treatment options for hepatocellular carcinoma concurrent with gastric adenocarcinoma.
View article: Hepatocellular carcinoma with gastric adenocarcinoma treated with atezolizumab and bevacizumab
Hepatocellular carcinoma with gastric adenocarcinoma treated with atezolizumab and bevacizumab Open
Hepatocellular carcinoma concurent with gastric adenocarcinoma is a rare but possible case. In addition, selecting an effective treatment for two primary cancers is often difficult. In this report, we present the first case of hepatocellul…
View article: Successful treatment of adalimumab for older Behçet's disease complicated with pulmonary artery thrombosis: A case report
Successful treatment of adalimumab for older Behçet's disease complicated with pulmonary artery thrombosis: A case report Open
Behçet's disease (BD) is a chronic systemic disorder characterized by inflammation of multiple organs, such as eyes, mucosa, skin, brain, joints, and vessels.1 Vascular manifestations, which consist of arterial involvements and venous invo…
View article: Novel MprF amino acid mutations contributing to daptomycin non-susceptibility
Novel MprF amino acid mutations contributing to daptomycin non-susceptibility Open
Background Daptomycin (DAP) is a cyclic lipopeptide antibiotic with potent bactericidal activity against gram-positive bacteria, and use to treat infections due to methicillin-resistant Staphylococcus aureus (MRSA). It was reported that Mp…
View article: Correction: Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis
Correction: Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis Open
[This corrects the article DOI: 10.1371/journal.pone.0202601.].
View article: Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis
Serum matrix metalloproteinase 3 levels are associated with an effect of iguratimod as add-on therapy to biological DMARDs in patients with rheumatoid arthritis Open
Our findings suggest that the ratios of the serum MMP-3 levels at baseline to those at 12 weeks could be used to predict remission in RA patients who are administered iguratimod as an add-on to bDMARDs.
View article: Antibody Inhibition of Properdin Prevents Complement-Mediated Intravascular and Extravascular Hemolysis
Antibody Inhibition of Properdin Prevents Complement-Mediated Intravascular and Extravascular Hemolysis Open
Paroxysmal nocturnal hemoglobinuria (PNH) is a serious blood disorder characterized by dysregulated complement activation on blood cells. Eculizumab, the current standard therapy and a humanized anti-C5 mAb, relieves anemia and thrombosis …
View article: A case of situs inversus with repeated sigmoid volvulus
A case of situs inversus with repeated sigmoid volvulus Open
An 81-year-old man who had been diagnosed as having situs inversus totalis and had suffered from repeated episodes of sigmoid volvulus was admitted with a history of right upper quadrant abdominal pain. Physical examination showed no evide…
View article: Nutritional status and management of risks due to physical therapy in patients hospitalized for long periods
Nutritional status and management of risks due to physical therapy in patients hospitalized for long periods Open
[Purpose] This study aimed to understand the nutritional status of patients hospitalized for long periods and the risk of physical therapy (PT) for such patients. [Subjects and Methods] Participants were selected from patients who were hos…
View article: A case report on a muco-submucosal elongated polyp of the duodenum treated with endoscopic resection
A case report on a muco-submucosal elongated polyp of the duodenum treated with endoscopic resection Open
Colonic muco-submucosal elongated polyps (MSEPs) are a new clinical entity first reported in 1994. The existence of long and slender polypoid lesion like an MSEP in the duodenum is rare. A 76-year-old man who complained of epigastralgia wa…