Yi Qian
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View article: The structural association between community environment and health vulnerability with the mediation role of sleep quality and social values among middle-aged and elderly adults in China: nationwide cross-sectional study
The structural association between community environment and health vulnerability with the mediation role of sleep quality and social values among middle-aged and elderly adults in China: nationwide cross-sectional study Open
Not applicable.
View article: Risk prediction of early-onset myocardial infarction using plasma proteomics, conventional risk factors, and polygenic risk score
Risk prediction of early-onset myocardial infarction using plasma proteomics, conventional risk factors, and polygenic risk score Open
Background and objectives Epidemiological trends indicate a concerning rise in early-onset cases of myocardial infarction (MI). We aimed to assess and compare the ability of plasma proteomics, conventional risk factors, and polygenic risk …
View article: Beyond Spatial Development: A Study on Rural Community Development in China Based on an Actor-Social Network Integration Approach
Beyond Spatial Development: A Study on Rural Community Development in China Based on an Actor-Social Network Integration Approach Open
Rural community development in China has made progress under the rapid implementation of the rural revitalization strategy; however, it has also revealed challenges such as an overemphasis on spatial construction, severe homogenization, an…
View article: From Space–Behavior Mismatch to Regional Integration: A Cross-Scale Social Network Analysis of Sustainable Rural Construction in Suburban China
From Space–Behavior Mismatch to Regional Integration: A Cross-Scale Social Network Analysis of Sustainable Rural Construction in Suburban China Open
Rapid urbanization in China has intensified spatial and social disparities between urban and rural areas, posing major challenges to sustainable rural development. Traditional top-down rural construction and evaluation models often neglect…
View article: Mitochondria-resident SBK3 confers protection against pressure overload-induced heart failure in mice
Mitochondria-resident SBK3 confers protection against pressure overload-induced heart failure in mice Open
Pathological myocardial hypertrophy, often caused by hypertension, is a well-established independent risk factor for heart failure. SBK3, a gene selectively expressed at relatively high levels in cardiac tissues, has an unclear functional …
View article: Study of AI algorithms on mpMRI and PHI for the diagnosis of clinically significant prostate cancer
Study of AI algorithms on mpMRI and PHI for the diagnosis of clinically significant prostate cancer Open
Combining multiple factors such as age, PSA, PIRADS score and PHI, adding AI algorithm based on mpMRI, the diagnostic accuracy of csPCa can be improved.
View article: Exploration of High-Risk HPV Genotyping Test as an Initial Screening Method for Cervical Cancer
Exploration of High-Risk HPV Genotyping Test as an Initial Screening Method for Cervical Cancer Open
Objective: The purpose of this study was to evaluate the clinical value of high-risk HPV typing as a primary screening method for cervical cancer. Methods: From July 2023 to June 2024, 871 women, aged 23 to 77 years old, with an average ag…
View article: Evaluating the application value of the modified Billroth-II with Braun anastomosis in laparoscopic distal gastric cancer radical surgery
Evaluating the application value of the modified Billroth-II with Braun anastomosis in laparoscopic distal gastric cancer radical surgery Open
Introduction: This retrospective study aims to compare the feasibility and efficacy of the modified Billroth-II with Braun (B-II Braun) reconstruction with the Roux-en-Y (R-Y) reconstruction following laparoscopic distal gastrectomy. Patie…
View article: Compensation preferences of home-based disabled beneficiaries in the long-term care insurance system in Guangzhou, China
Compensation preferences of home-based disabled beneficiaries in the long-term care insurance system in Guangzhou, China Open
This study explores the preferences and willingness-to-pay of home-based disabled elderly individuals for long-term care insurance (LTCI) compensation mechanisms in Guangzhou, China, using a discrete choice experiment. The research aims to…
View article: Flourishing and its influencing factors among maintenance hemodialysis patients in Shanghai, China: a cross-sectional study
Flourishing and its influencing factors among maintenance hemodialysis patients in Shanghai, China: a cross-sectional study Open
Background Maintenance hemodialysis (MHD) patients face substantial psychological challenges that impacting their overall quality of life. Flourishing, a concept within positive psychology, refers to a state of mental well-being and person…
View article: Nonparametric Probabilistic Prediction of Ultra-Short-Term Wind Power Based on MultiFusion–ChronoNet–AMC
Nonparametric Probabilistic Prediction of Ultra-Short-Term Wind Power Based on MultiFusion–ChronoNet–AMC Open
Accurate forecasting is crucial for enhancing the flexibility and controllability of power grids. Traditional forecasting methods mainly focus on modeling based on a single data source, which leads to an inability to fully capture the unde…
View article: Cumulative remnant cholesterol and major adverse cardiovascular events among adults with type 2 diabetes
Cumulative remnant cholesterol and major adverse cardiovascular events among adults with type 2 diabetes Open
Background Individuals with type 2 diabetes are prone to dyslipidemia. The relationship of cumulative exposure to elevated remnant cholesterol (RC) with major adverse cardiovascular events (MACEs) remains unclear for individuals with type …
View article: Rapid defect prediction and optimisation method for Ti-modified AlCuMg alloys processed by laser powder-bed fusion
Rapid defect prediction and optimisation method for Ti-modified AlCuMg alloys processed by laser powder-bed fusion Open
Ti-modified AlCuMg alloys have demonstrated great potential in improving the printability and mechanical properties of conventional Al alloys processed by laser powder-bed fusion (LPBF). However, an effective material design method, which …
View article: Overexpression of MIR-302C-3P Leads to Apoptosis in Human Renal Mesangial Cells
Overexpression of MIR-302C-3P Leads to Apoptosis in Human Renal Mesangial Cells Open
Objective: The apoptosis of glomerular mesangial cells is closely related to the occurrence and development of diabetic nephropathy (DN). However, the mechanism remains unclear. In the present study, we found that the high-glucose cultures…
View article: Development of monoclonal antibodies against <i>P. gingivalis</i> Mfa1 and their protective capacity in an experimental periodontitis model
Development of monoclonal antibodies against <i>P. gingivalis</i> Mfa1 and their protective capacity in an experimental periodontitis model Open
Porphyromonas gingivalis ( P. gingivalis ), a gram-negative, black-pigmented anaerobe, is a major etiological agent and a leading cause of periodontitis. Fimbriae protein Mfa1 is a key virulence factor of P. gingivalis and plays a crucial …
View article: From Estimands to Robust Inference of Treatment Effects in Platform Trials
From Estimands to Robust Inference of Treatment Effects in Platform Trials Open
A platform trial is an innovative clinical trial design that uses a master protocol to evaluate multiple treatments, where patients are often assigned to different subsets of treatment arms based on individual characteristics, enrollment t…
View article: Manifestation of Primary Care Features in Shanghai’s Family Doctor Service and Their Impact on Health: A Mixed-Methods Study
Manifestation of Primary Care Features in Shanghai’s Family Doctor Service and Their Impact on Health: A Mixed-Methods Study Open
CONTEXT: Mainland China’s primary care system significantly differs from those in developed countries in design, resources, and capabilities. OBJECTIVE: To evaluate the real-life experiences and impacts of primary care functional features …
View article: Less is more: Embracing sparsity and interpolation with Esiformer for time series forecasting
Less is more: Embracing sparsity and interpolation with Esiformer for time series forecasting Open
Time series forecasting has played a significant role in many practical fields. But time series data generated from real-world applications always exhibits high variance and lots of noise, which makes it difficult to capture the inherent p…
View article: Clarifying the Role of the Mantel-Haenszel Risk Difference Estimator in Randomized Clinical Trials
Clarifying the Role of the Mantel-Haenszel Risk Difference Estimator in Randomized Clinical Trials Open
The Mantel-Haenszel (MH) risk difference estimator, commonly used in randomized clinical trials for binary outcomes, calculates a weighted average of stratum-specific risk difference estimators. Traditionally, this method requires the stri…
View article: Socioeconomic disparities in the association of age at first live birth with incident stroke among Chinese parous women: A prospective cohort study
Socioeconomic disparities in the association of age at first live birth with incident stroke among Chinese parous women: A prospective cohort study Open
Older AFLB was associated with higher risks of incident stroke and its subtypes among Chinese parous women, with stronger associations between AFLB and ischaemic stroke among rural-low-SES participants. Targeted medical advice for pregnant…