Yuho Ono
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View article: MicroRNA-21 is a potential therapeutic agent targeting Tgfbi and mitigating high-fat-diet-induced liver disease and cancer
MicroRNA-21 is a potential therapeutic agent targeting Tgfbi and mitigating high-fat-diet-induced liver disease and cancer Open
View article: miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice
miR-21: A therapeutic target for delaying severe liver disease and hepatocellular carcinoma in high-fat-diet-fed mice Open
Liver disease, including hepatocellular carcinoma (HCC), is a major global health concern, claiming approximately 2 million lives worldwide annually, yet curative treatments remain elusive. In this study, we aimed to investigate the role o…
View article: Spontaneous Tumor Lysis Syndrome Secondary to Metastatic Pancreatic Adenocarcinoma
Spontaneous Tumor Lysis Syndrome Secondary to Metastatic Pancreatic Adenocarcinoma Open
Spontaneous tumor lysis syndrome (STLS) secondary to metastatic pancreatic adenocarcinoma is a rare clinical phenomenon. An 86-year-old woman with a history of pancreatic cysts presented to the emergency department with progressive fatigue…
View article: DISEASE MODELING IN INFLAMMATORY BOWEL DISEASE (IBD) USING PATIENT-DERIVED EXPLANTS (PDE) REVEALS CHEMOKINES AS A RELEVANT TARGET OF JAK INHIBITION
DISEASE MODELING IN INFLAMMATORY BOWEL DISEASE (IBD) USING PATIENT-DERIVED EXPLANTS (PDE) REVEALS CHEMOKINES AS A RELEVANT TARGET OF JAK INHIBITION Open
Despite a recent explosion of approved drugs for IBD that primarily target cytokines and T-cell trafficking, therapeutic response rates remain low (30-50 %), underscoring the need for more efficacious treatments with fewer side effects. Fr…
View article: Immune microenvironment and lymph node yield in colorectal cancer
Immune microenvironment and lymph node yield in colorectal cancer Open
View article: Case Report and Mini-Review: Sarcina ventriculi in the Stomach of an 80-Year-Old Female
Case Report and Mini-Review: Sarcina ventriculi in the Stomach of an 80-Year-Old Female Open
In infectious disease and clinical microbiology, rarely encountered species are often of special concern simply by virtue of their unfamiliarity, especially in settings of complicated underlying disease. This is all the more so when the in…
View article: A Case of Prostate Cancer Harboring Androgen Receptor T878A Progesterone-Responsive Mutant Emerging After Abiraterone Acetate Treatment Responding to Darolutamide
A Case of Prostate Cancer Harboring Androgen Receptor T878A Progesterone-Responsive Mutant Emerging After Abiraterone Acetate Treatment Responding to Darolutamide Open
Article Tools CASE REPORTS Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/PO.21.00091 JCO Precision Oncology no. 6 (…
View article: Attitudes Regarding the World Health Organization–Recommended Term <i>Sessile Serrated Lesion</i> : Results From an International Survey
Attitudes Regarding the World Health Organization–Recommended Term <i>Sessile Serrated Lesion</i> : Results From an International Survey Open
To the Editor.—In our recent descriptive timeline of the nomenclature changes for sessile serrated lesion of the colorectum,1 we referenced our international survey assessing pathologist attitudes regarding the World Health Organization (W…
View article: From Mixed Hyperplastic/Adenomatous Polyp to Sessile Serrated Lesion: A Long and Winding Road for Long and Winding Crypts
From Mixed Hyperplastic/Adenomatous Polyp to Sessile Serrated Lesion: A Long and Winding Road for Long and Winding Crypts Open
Context.— During the past 3 decades, numerous articles in the literature have offered terminology, diagnostic criteria, and consensus recommendations regarding the entity currently referred to by the World Health Organization as sessile se…