Yuhong Ren
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View article: Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone
Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone Open
View article: Development of an mRNA vaccine encoding IHNV glycoprotein protects rainbow trout (Oncorhynchus mykiss) from infection
Development of an mRNA vaccine encoding IHNV glycoprotein protects rainbow trout (Oncorhynchus mykiss) from infection Open
mRNA vaccines have demonstrated significant potential in preventing human diseases and controlling livestock infections. However, the application of mRNA vaccines in aquaculture, especially on fish, remains limited. Infectious hematopoieti…
View article: Evaluating Binary Molybdenum Alloys as Strong and Ductile High-Temperature Materials
Evaluating Binary Molybdenum Alloys as Strong and Ductile High-Temperature Materials Open
Molybdenum alloys as refractory alloys can provide strength levels at operating temperatures higher than that of Ni-base superalloys, yet their ductility is usually inferior to Ni-base alloys. Currently, commercialized Mo alloys are much f…
View article: Dental floss traction-assisted precut sphincterotomy for difficult biliary cannulation in elongated papilla
Dental floss traction-assisted precut sphincterotomy for difficult biliary cannulation in elongated papilla Open
View article: Site-specific PEGylation of Recombinant Protein SAC-TRAIL and Characterization of the Effect on Antitumor Activity
Site-specific PEGylation of Recombinant Protein SAC-TRAIL and Characterization of the Effect on Antitumor Activity Open
Background Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anti-tumor agent with selective cytotoxicity across a broad spectrum of tumor cell lines. In previous studies, we engineered a recombinant protein dr…
View article: Rolling Circle Amplification-Based Self-Assembled Cpg Nanoparticles: Immune Activation and Prevention of Edwardsiella Piscicida
Rolling Circle Amplification-Based Self-Assembled Cpg Nanoparticles: Immune Activation and Prevention of Edwardsiella Piscicida Open
View article: Delivery of dsRNA to improve RNAi efficiency by cell-penetrating disulfide polymer for spodoptera frugiperda control
Delivery of dsRNA to improve RNAi efficiency by cell-penetrating disulfide polymer for spodoptera frugiperda control Open
The application of RNA is regarded as innovative and sustainable, and it has shown excellent control efficiency against pest control in the world. However, the efficiency of RNAi in insects could be more inefficient and unreliable, and exp…
View article: Molecular Detection and Genotyping of Enterocytozoon bieneusi in Pigs in Shanxi Province, North China
Molecular Detection and Genotyping of Enterocytozoon bieneusi in Pigs in Shanxi Province, North China Open
Enterocytozoon bieneusi is a common opportunistic intestinal pathogen that can cause acute diarrhea in immunosuppressed humans and animals. Though E. bieneusi has been widely detected in pigs around the world, little is known of its preval…
View article: A CRISPRi mediated self-inducible system for dynamic regulation of TCA cycle and improvement of itaconic acid production in Escherichia coli
A CRISPRi mediated self-inducible system for dynamic regulation of TCA cycle and improvement of itaconic acid production in Escherichia coli Open
Itaconic acid (ITA), an effective alternative fossil fuel, derives from the bypass pathway of the tricarboxylic acid (TCA) cycle. Therefore, the imbalance of metabolic flux between TCA cycle and ITA biosynthetic pathway seriously limits th…
View article: Screening and characterization of a nitrilase with significant nitrile hydratase activity
Screening and characterization of a nitrilase with significant nitrile hydratase activity Open
Purpose We screened nitrilases with significant nitrile hydratase activity to exploit their potential in aromatic amide biosynthesis. We also investigated the factors affecting their hydration activity to support further research on aromat…
View article: Rapid Mining of Novel α-Glucosidase and Lipase Inhibitors from Streptomyces sp. HO1518 Using UPLC-QTOF-MS/MS
Rapid Mining of Novel α-Glucosidase and Lipase Inhibitors from Streptomyces sp. HO1518 Using UPLC-QTOF-MS/MS Open
A rapid and sensitive method using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) was applied for the analysis of the metabolic profile of acarviostatin-containing aminooligosacch…
View article: Diversion of metabolic flux towards 5-deoxy(iso)flavonoid production via enzyme self-assembly in Escherichia coli
Diversion of metabolic flux towards 5-deoxy(iso)flavonoid production via enzyme self-assembly in Escherichia coli Open
View article: Acylated Aminooligosaccharides from the Yellow Sea Streptomyces sp. HO1518 as Both α-Glucosidase and Lipase Inhibitors
Acylated Aminooligosaccharides from the Yellow Sea Streptomyces sp. HO1518 as Both α-Glucosidase and Lipase Inhibitors Open
Three new acylated aminooligosaccharide (1–3), along with five known congeners (4–8), were isolated from the marine-derived Streptomyces sp. HO1518. Their structures were fully elucidated by extensive spectroscopic analysis, mainly based o…
View article: Cadmium sulfide net framework nanoparticles for photo-catalyzed cell redox
Cadmium sulfide net framework nanoparticles for photo-catalyzed cell redox Open
CdS net framework (CdS-NF) nanoparticles were synthesized under mild reaction conditions and used to construct an Escherichia coli–CdS-NF hybrid system which used NADH regeneration to promote the redox reaction.
View article: Reversible photocontrol of oxidase activity by inserting a photosensitive domain into the oxidase
Reversible photocontrol of oxidase activity by inserting a photosensitive domain into the oxidase Open
Background Photocontrol of protein activity has become a helpful strategy for regulating biological pathways. Herein, a method for the precise and reversible photocontrol of oxidase activity was developed by using the conformational change…
View article: Photocontrolled reversible self-assembly of dodecamer nitrilase
Photocontrolled reversible self-assembly of dodecamer nitrilase Open
An efficient method was developed for the photocontrolled assembly and disassembly of dodecamer nitrilase and for scaffold-free reversible self-assembly of multiple oligomeric enzymes in vivo and in vitro, providing new ideas and methods f…
View article: Assembly of cellulases with synthetic protein scaffolds in vitro
Assembly of cellulases with synthetic protein scaffolds in vitro Open
Background Enzymatic cascades in metabolic pathways are spatially organized in such a way as to facilitate the flow of substrates. The construction of artificial cellulase complexes that mimic natural multienzyme assemblies can potentially…