Yuichiro Nishida
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View article: Nutrient patterns and mortality: results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study
Nutrient patterns and mortality: results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study Open
The results of the present study suggest that increased adherence to nutrient patterns rich in folate, carotene, fiber, vitamin C, potassium, iron, and retinol or moderate adherence to unsaturated fatty acids and vitamin E are associated w…
View article: Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian never-smokers
Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian never-smokers Open
Background Lung adenocarcinoma in never-smokers is a major public health burden, especially among East Asian women. Polygenic risk scores (PRSs) are promising for risk stratification but are primarily developed in European-ancestry populat…
View article: Nutrient patterns and mortality: Results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study
Nutrient patterns and mortality: Results from the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study Open
Background : The consumption of a healthy diet may play an important role in the prevention of noncommunicablediseases (NCDs). Although the associationsbetween nutrient patterns and cardiometabolic risk factors or NCDs have been examined, …
View article: High-Throughput Measurement of Oxidative Stress Indicators: d-ROMs and BAP Assays in a 384-well Plate Format
High-Throughput Measurement of Oxidative Stress Indicators: d-ROMs and BAP Assays in a 384-well Plate Format Open
The body’s oxidative balance is regulated by systems that produce and eliminate reactive oxygen species (ROS), and disruptions in this balance can contribute to the development of lifestyle-related diseases. d-ROMs and BAP tests, which eva…
View article: Evaluation of the Postprandial-Hyperglycemia-Suppressing Effects and Safety of Short-Term Intake of Mulberry Leaf and Water Chestnut Tea: A Randomized Double-Blind Placebo-Controlled Crossover Trial
Evaluation of the Postprandial-Hyperglycemia-Suppressing Effects and Safety of Short-Term Intake of Mulberry Leaf and Water Chestnut Tea: A Randomized Double-Blind Placebo-Controlled Crossover Trial Open
Background/Objectives: Postprandial hyperglycemia is a risk factor for diabetes and cardiovascular diseases, even in healthy individuals. Kanzaki mulberry leaf and water chestnut tea (MW tea), a blend of mulberry (Morus alba) leaves and wa…
View article: Higher Nutritional Adequacy Is Associated With Lower All-Cause Mortality: Findings From the J-MICC Cohort Study
Higher Nutritional Adequacy Is Associated With Lower All-Cause Mortality: Findings From the J-MICC Cohort Study Open
Background: Although nutrient intake has been associated with mortality, little is known about the effect of nutritional balance in the diet on mortality. We evaluated the association between a nutritionally balanced diet and all-cause, ca…
View article: Multi‐Trait Polygenic Risk Score, Nongenetic Determinants, and Cardiovascular Disease Death: A Cohort Study of 14 086 Japanese Individuals
Multi‐Trait Polygenic Risk Score, Nongenetic Determinants, and Cardiovascular Disease Death: A Cohort Study of 14 086 Japanese Individuals Open
Background Although utility of composite trait‐specific polygenic risk score (multi‐trait PRS) has been examined among European ancestries, few studies investigated among East Asians and incorporated modifiable risk factors. We examined th…
View article: MOTS-c modulates skeletal muscle function by directly binding and activating CK2
MOTS-c modulates skeletal muscle function by directly binding and activating CK2 Open
MOTS-c is a mitochondrial microprotein that improves metabolism. Here, we demonstrate CK2 is a direct and functional target of MOTS-c. MOTS-c directly binds to CK2 and activates it in cell-free systems. MOTS-c administration to mice preven…
View article: Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers
Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers Open
Background Lung adenocarcinoma (LUAD) in never-smokers is a major public health burden, especially among East Asian women. Polygenic risk scores (PRSs) are promising for risk stratification but are primarily developed in European-ancestry …
View article: Interaction between Habitual Green Tea and Coffee Consumption and ACTN3 Genotype in Association with Skeletal Muscle Mass and Strength in Middle-Aged and Older Adults
Interaction between Habitual Green Tea and Coffee Consumption and ACTN3 Genotype in Association with Skeletal Muscle Mass and Strength in Middle-Aged and Older Adults Open
Our findings suggest that the skeletal muscle strength benefits associated with habitual green tea consumption may be contingent upon sex and the ACTN3 genotype.
View article: Association between oxidative balance score and inflammatory markers in middle‐aged and older Japanese people
Association between oxidative balance score and inflammatory markers in middle‐aged and older Japanese people Open
Purpose This study aimed to investigate the association between oxidative balance score (OBS), wherein higher OBSs indicate lower oxidative stress, and high‐sensitivity C‐reactive protein (hs‐CRP), as well as inflammatory scores, in a larg…
View article: Dietary diversity and the risk of metabolic syndrome in a Japanese population: An analysis of baseline cross-sectional data from the J-MICC study
Dietary diversity and the risk of metabolic syndrome in a Japanese population: An analysis of baseline cross-sectional data from the J-MICC study Open
Background: With the increasing burden of metabolic syndrome, it is crucial to focus on lifestyle interventions to reduce the risk. Diet is a modifiable factor that can reduce the risk of metabolic syndrome. Methods: We examined the associ…
View article: Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study
Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study Open
Objective: Although small fish are an important source of micronutrients, the relationship between their intake and mortality remains unclear. This study aimed to clarify the association between intake of small fish and all-cause and cause…
View article: Seven‐plus hours of daily sedentary time and the subsequent risk of breast cancer: Japan Multi‐Institutional Collaborative Cohort Study
Seven‐plus hours of daily sedentary time and the subsequent risk of breast cancer: Japan Multi‐Institutional Collaborative Cohort Study Open
This study aimed to investigate the association between daily sedentary time and the risk of breast cancer (BC) in a large Japanese population. The participants were 36,023 women aged 35–69 years from the Japan Multi‐Institutional Collabor…
View article: Association Between Awareness of Limiting Food Intake and All-cause Mortality: A Cohort Study in Japan
Association Between Awareness of Limiting Food Intake and All-cause Mortality: A Cohort Study in Japan Open
Awareness of limiting food intake had a limited effect on reducing all-cause mortality risk.
View article: The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults
The Association between Oxidative Balance Score and Urinary Levels of 8-Hydroxydeoxyguanosine among Japanese Adults Open
The oxidative balance score (OBS), wherein higher OBSs indicate lower oxidative stress, was designed to assess a composite measure of multiple pro-oxidant and antioxidant effects on an individual’s oxidative stress status. This study aimed…
View article: Association Between the Appendicular Extracellular-to-Intracellular Water Ratio and All-Cause Mortality: A 10-Year Longitudinal Study
Association Between the Appendicular Extracellular-to-Intracellular Water Ratio and All-Cause Mortality: A 10-Year Longitudinal Study Open
The appendicular extracellular-to-intracellular water ratio (A-E/I) is a potential marker of skeletal muscle quality, reflecting the balance of water distribution between the extracellular and intracellular compartments of the appendicular…
View article: Association between green tea and coffee consumption and body iron storage in Japanese men and women: a cross-sectional study from the J-MICC Study Saga
Association between green tea and coffee consumption and body iron storage in Japanese men and women: a cross-sectional study from the J-MICC Study Saga Open
Purpose This study examined the association between daily green tea and coffee consumption and body iron stores among Japanese middle-aged and older adults. Methods This cross-sectional study used data obtained from 2005 to 2007. A total o…
View article: GWAS of Folate Metabolism With Gene–environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study
GWAS of Folate Metabolism With Gene–environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study Open
The present GWAS revealed the folate metabolism-associated genetic loci and gene-environment interactions with drinking and physical activity in Japanese, suggesting the possibility of future personalized cardiovascular disease prevention.
View article: Exercise Capacity and Ventilatory Efficiency in Patients With Pulmonary Arterial Hypertension
Exercise Capacity and Ventilatory Efficiency in Patients With Pulmonary Arterial Hypertension Open
Background The symptom for identification of pulmonary arterial hypertension (PAH) is dyspnea on exertion, with a concomitant decrease in exercise capacity. Even patients with hemodynamically improved PAH may have impaired exercise toleran…
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Issue Information Open
No abstract is available for this article.
View article: Dose-response relationship between daily step count and prevalence of sarcopenia: A cross-sectional study
Dose-response relationship between daily step count and prevalence of sarcopenia: A cross-sectional study Open
The study found a significant inverse association between daily step count and the prevalence of sarcopenia, with the association plateauing when the daily step count exceeded approximately 8000 steps. These findings suggest that 8000 step…
View article: Refractory Retroperitoneal Abscess Due to Anastomosis Leakage after Transanal Total Mesorectal Excision Combined with Robotic Rectal Resection with Diverting Ileostomy: A Case Report
Refractory Retroperitoneal Abscess Due to Anastomosis Leakage after Transanal Total Mesorectal Excision Combined with Robotic Rectal Resection with Diverting Ileostomy: A Case Report Open
症例は54歳の男性で，下部直腸癌（RbRa 2型cT3N1aM0 cStage IIIb）の診断で術前化学療法後に手術を予定した．通常の前処置を行ったが，便排泄は不完全で手術直前まで泥状便が持続した．Transanal total mesorectal excision（以下，TaTMEと略記）併用ロボット支援下部分的内肛門括約筋切除術とD2郭清を行い，吻合は1列全層縫合を行った．併せて回腸人工肛門造設術を行った．術直後から泥状便が持続し，術後3日目から炎症反応の著明な上昇…