Yasuhiro Ueda
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View article: Subcutaneous sarcoidosis mimicking an infiltrative malignant soft-tissue tumor: Two case reports and a literature review
Subcutaneous sarcoidosis mimicking an infiltrative malignant soft-tissue tumor: Two case reports and a literature review Open
Subcutaneous sarcoidosis is an extremely rare inflammatory disease, and the imaging characteristics are unknown. A 72-year-old woman had an elastic hard nodule, which was gradually growing, on her left upper extremity that had been present…
View article: CD44 as a pathological marker for the early detection of calcineurin inhibitor-induced nephrotoxicity post kidney transplantation
CD44 as a pathological marker for the early detection of calcineurin inhibitor-induced nephrotoxicity post kidney transplantation Open
Long-term calcineurin inhibitor (CNI) administration causes irreversible nephrotoxicity. Therefore, early CNI-induced nephrotoxicity detection is necessary for patients who will need long-term CNI administration. There is no pathological i…
View article: Fr581 EVALUATION OF SEQUENTIAL CHANGES IN THE INTESTINAL FLORA OF PATIENTS TAKING LOW-DOSE ASPIRIN AND A PROTON-PUMP INHIBITOR
Fr581 EVALUATION OF SEQUENTIAL CHANGES IN THE INTESTINAL FLORA OF PATIENTS TAKING LOW-DOSE ASPIRIN AND A PROTON-PUMP INHIBITOR Open
View article: <i>O</i>-GlcNAcylation-mediated regulation of FOXM1 expression through its ubiquitination in a human gastric adenocarcinoma cell line, NUGC-3
<i>O</i>-GlcNAcylation-mediated regulation of FOXM1 expression through its ubiquitination in a human gastric adenocarcinoma cell line, NUGC-3 Open
O-GlcNAcylation is a dynamic post-translational modification of cytonuclear molecules and regulated by only two enzymes, OGT and OGA, which add and remove a glucose metabolite, UDP-GlcNAc, respectively. Previously, we reported that augment…
View article: Distribution of Deep Gray Matter Lesions on Magnetic Resonance Imaging in Lymphomatosis Cerebri
Distribution of Deep Gray Matter Lesions on Magnetic Resonance Imaging in Lymphomatosis Cerebri Open
We herein report the distribution of gray matter lesions on magnetic resonance imaging (MRI) in two patients with lymphomatosis cerebri (LC). In our patients, the fluid-attenuated inversion recovery sequence of brain MRI demonstrated a bil…
View article: <i>O</i>-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression
<i>O</i>-GlcNAcylation-mediated degradation of FBXL2 stabilizes FOXM1 oncogenic transcription factor to promote cancer progression Open
O-GlcNAcylation is a dynamic and reversible post-translational modification of cytonuclear molecules and critical for intracellular signaling. The modification is regulated by only two enzymes, OGT and OGA, which add and remove a glucose m…
View article: <i>O</i>-GlcNAcylation stabilizes FOXM1 protein via suppression of its poly-ubiquitination
<i>O</i>-GlcNAcylation stabilizes FOXM1 protein via suppression of its poly-ubiquitination Open
O-GlcNAcylation is a post-translational modifications regulating dynamic intracellular signaling by two enzymes, OGT and OGA, which add and remove the modification, respectively. In many types of cancer cells, O-GlcNAcylation is elevated a…
View article: Bilateral Frontal Lobe Vasogenic Edema Resulting from Hypertrophic Pachymeningitis due to Granulomatosis with Polyangiitis
Bilateral Frontal Lobe Vasogenic Edema Resulting from Hypertrophic Pachymeningitis due to Granulomatosis with Polyangiitis Open
A 61-year-old woman presented with a 1-month history of decreased activities of daily living. Magnetic resonance imaging revealed abnormal intensities of the bilateral frontal lobes and enhancement of the thickened dura matter. A biopsy of…
View article: Enteral nutrient gel causes formation of a huge gastric bezoar
Enteral nutrient gel causes formation of a huge gastric bezoar Open
A 58-year-old Asian woman hung herself. When emergency medical service arrived, she was under cardiopulmonary arrest with asystolic rhythm. Sixty minutes later, her circulation was restored and she was then transferred from a rural hospita…
View article: A Case of Gastrointestinal Stromal Tumor of the Duodenum with Fistula Formation
A Case of Gastrointestinal Stromal Tumor of the Duodenum with Fistula Formation Open
症例は60歳台，男性．平成25年７月腹痛，黒色便を主訴に近医を受診し，右下腹部に巨大腫瘤を触知した．CTにて巨大腹腔内腫瘍を認め，精査加療目的で当院紹介となった．上部消化管内視鏡検査所見で十二指腸下行脚に瘻孔がみられ，瘻孔を通じて広範囲に広がる潰瘍性病変を認め，生検でGISTと診断された．CTおよびMRI検査所見からは瘻孔形成を伴う巨大小腸GISTが疑われ，PET-CT検査所見では腹膜播種や遠隔転移を認めなかった．出血・発熱も伴っていたので手術を施行した．術中所見で腫瘍は膵…