Yujian Lan
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View article: The impact of aging on achilles tendon ossification in mice
The impact of aging on achilles tendon ossification in mice Open
Atp5o, Mmp2 and Mmp13 were identified as relevant signature genes for the effects of aging on Achilles tendon ossification in mice. Atp5o, Mmp2, and Mmp13 may influence tendon ossification by affecting mitochondrial function as well as ext…
View article: Identification and Characterisation of Potential Targets for N6-methyladenosine (m6A) Modification during Intervertebral Disc Degeneration
Identification and Characterisation of Potential Targets for N6-methyladenosine (m6A) Modification during Intervertebral Disc Degeneration Open
Background: The mechanism for RNA methylation during disc degeneration is unclear. The aim of this study was to identify N6-methyladenosine (m6A) markers and therapeutic targets for the prevention and treatment of intervertebral disc degen…
View article: Elucidating common biomarkers and pathways of osteoporosis and aortic valve calcification: insights into new therapeutic targets
Elucidating common biomarkers and pathways of osteoporosis and aortic valve calcification: insights into new therapeutic targets Open
View article: Animal models of tendon calcification: Past, present, and future
Animal models of tendon calcification: Past, present, and future Open
Tendon calcification is a common clinical condition that frequently occurs as a complication after tendon injury and surgery, or as an expression of fibrodysplasia ossificans progressiva. This condition can be referred to by various names …
View article: Sirtuins in intervertebral disc degeneration: current understanding
Sirtuins in intervertebral disc degeneration: current understanding Open
Background Intervertebral disc degeneration (IVDD) is one of the etiologic factors of degenerative spinal diseases, which can lead to a variety of pathological spinal conditions such as disc herniation, spinal stenosis, and scoliosis. IVDD…
View article: Advances focusing on the application of decellularization methods in tendon-bone healing
Advances focusing on the application of decellularization methods in tendon-bone healing Open
View article: Targeting signaling pathways in osteosarcoma: Mechanisms and clinical studies
Targeting signaling pathways in osteosarcoma: Mechanisms and clinical studies Open
Osteosarcoma (OS) is a highly prevalent bone malignancy among adolescents, accounting for 40% of all primary malignant bone tumors. Neoadjuvant chemotherapy combined with limb‐preserving surgery has effectively reduced patient disability a…
View article: External stimulation: A potential therapeutic strategy for tendon-bone healing
External stimulation: A potential therapeutic strategy for tendon-bone healing Open
Injuries at the tendon-bone interface are very common in the field of sports medicine, and healing at the tendon-bone interface is complex. Injuries to the tendon-bone interface can seriously affect a patient’s quality of life, so it is es…