Yujiro Yoshihara
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View article: Category-Specific Brain Structural Changes in Psychiatric Disorders and Conditions Using Well-Qualified Harmonization Dataset from Multiple Sites
Category-Specific Brain Structural Changes in Psychiatric Disorders and Conditions Using Well-Qualified Harmonization Dataset from Multiple Sites Open
Background Large-scale, multi-site brain magnetic resonance imaging (MRI) studies have revealed neuroanatomical alterations in various psychiatric disorders. However, site-specific differences—such as sampling and measurement biases—and th…
View article: Computational mechanisms of neuroimaging biomarkers uncovered by multicenter resting-state fMRI connectivity variation profile
Computational mechanisms of neuroimaging biomarkers uncovered by multicenter resting-state fMRI connectivity variation profile Open
Resting-state functional connectivity (rsFC) is increasingly used to develop biomarkers for psychiatric disorders. Despite progress, development of the reliable and practical FC biomarker remains an unmet goal, particularly one that is cli…
View article: 557. GLUTAMATE, GLUTAMINE, AND GABA LEVELS IN ADULTS WITH AUTISM SPECTRUM DISORDER: A 7T MRS STUDY
557. GLUTAMATE, GLUTAMINE, AND GABA LEVELS IN ADULTS WITH AUTISM SPECTRUM DISORDER: A 7T MRS STUDY Open
Background Alterations in excitatory and inhibitory neuronal tones are implicated in the pathophysiology of autism spectrum disorder (ASD). Excitatory neurotransmission is primarily mediated by glutamate (Glu) and its precursor, glutamine …
View article: Enhancement of the left frontoparietal network through real‐time <scp>functional magnetic resonance imaging</scp> functional connectivity–informed neurofeedback and its impact on working memory in schizophrenia: A pilot study
Enhancement of the left frontoparietal network through real‐time <span>functional magnetic resonance imaging</span> functional connectivity–informed neurofeedback and its impact on working memory in schizophrenia: A pilot study Open
Aim Cognitive impairment in schizophrenia shows limited improvement with pharmacotherapy, indicating a need for effective treatment. The frontoparietal network supports working memory, and a biomarker has successfully predicted performance…
View article: Unsupervised feature computation-based feature selection robustly extracted resting-state functional connectivity patterns related to mental disorders
Unsupervised feature computation-based feature selection robustly extracted resting-state functional connectivity patterns related to mental disorders Open
Research on biomarkers for predicting psychiatric disorders from resting-state functional connectivity (FC) is advancing. While the focus has primarily been on the discriminative performance of biomarkers by machine learning, identificatio…
View article: NEUROBIOLOGICAL OVERLAPS AND DIFFERENCES IN METHAMPHETAMINE-INDUCED PSYCHOSIS AND SCHIZOPHRENIA: A RESTING-STATE FMRI AND MACHINE LEARNING STUDY
NEUROBIOLOGICAL OVERLAPS AND DIFFERENCES IN METHAMPHETAMINE-INDUCED PSYCHOSIS AND SCHIZOPHRENIA: A RESTING-STATE FMRI AND MACHINE LEARNING STUDY Open
Background Methamphetamine-induced psychosis (MIP) is characterized by transient episodes, but a substantial portion persists long-term (Wearne &Cornish 2018). While symptom similarities exist between MIP and schizophrenia (Sz), their neur…
View article: Nuclei-specific abnormalities of amygdala functional connectivity and their changes after multiple types of treatments for depression: a multicenter MRI study
Nuclei-specific abnormalities of amygdala functional connectivity and their changes after multiple types of treatments for depression: a multicenter MRI study Open
Exploring the neurobiological effects of various treatments for depression is pivotal in elucidating shared and unique mechanisms of action that may explain commonalities and differences in treatment outcomes. The amygdala, consisting of s…
View article: Gray and White Matter Microstructural Alterations in Major Depressive Disorder: A Multi-Center Diffusion Imaging Study
Gray and White Matter Microstructural Alterations in Major Depressive Disorder: A Multi-Center Diffusion Imaging Study Open
Alterations in gray matter (GM) and white matter (WM) microstructure have been implicated in the pathophysiology of major depressive disorder (MDD). While previous neuroimaging studies have primarily focused on WM microstructural changes, …
View article: Electroconvulsive therapy-specific volume changes in nuclei of the amygdala and their relationship to long-term anxiety improvement in depression
Electroconvulsive therapy-specific volume changes in nuclei of the amygdala and their relationship to long-term anxiety improvement in depression Open
View article: Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism
Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism Open
View article: Generalisable functional imaging classifiers of schizophrenia have multifunctionality as trait, state, and staging biomarkers
Generalisable functional imaging classifiers of schizophrenia have multifunctionality as trait, state, and staging biomarkers Open
Schizophrenia spectrum disorder (SSD) is one of the top causes of disease burden; similar to other psychiatric disorders, SSD lacks widely applicable and objective biomarkers. This study aimed to introduce a novel resting-state functional …
View article: Segmentation and Volume Estimation of the Habenula Using Deep Learning in Patients With Depression
Segmentation and Volume Estimation of the Habenula Using Deep Learning in Patients With Depression Open
View article: Paving the way for precision treatment of psychiatric symptoms with functional connectivity neurofeedback
Paving the way for precision treatment of psychiatric symptoms with functional connectivity neurofeedback Open
Introduction Major depressive disorder (MDD) remains challenging to treat, with many patients failing to respond adequately to existing therapies. Patients with MDD have heterogeneous subsets of symptoms with differing underlying neural ab…
View article: Computational Mechanisms of Neuroimaging Biomarkers Uncovered by Multicenter Resting-State fMRI Connectivity Variation Profile
Computational Mechanisms of Neuroimaging Biomarkers Uncovered by Multicenter Resting-State fMRI Connectivity Variation Profile Open
Resting-state functional connectivity (rsFC) is increasingly used to develop biomarkers for psychiatric disorders. Despite progress, development of the reliable and practical FC biomarker remains an unmet goal, particularly one that is cli…
View article: Generalisable functional imaging classifiers of schizophrenia have multifunctionality as trait, state, and staging biomarkers
Generalisable functional imaging classifiers of schizophrenia have multifunctionality as trait, state, and staging biomarkers Open
Schizophrenia spectrum disorder (SSD) is one of the top causes of disease burden; similar to other psychiatric disorders, SSD lacks widely applicable and objective biomarkers. This study aimed to introduce a novel resting-state functional …
View article: Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study
Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study Open
View article: Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study
Generalizable neuromarker for autism spectrum disorder across imaging sites and developmental stages: A multi-site study Open
Autism spectrum disorder (ASD) is a lifelong condition, and its underlying biological mechanisms remain elusive. The complexity of various factors, including inter-site and development-related differences, makes it challenging to develop g…
View article: Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders
Distinctive alterations in the mesocorticolimbic circuits in various psychiatric disorders Open
Aim Increasing evidence suggests that psychiatric disorders are linked to alterations in the mesocorticolimbic dopamine‐related circuits. However, the common and disease‐specific alterations remain to be examined in schizophrenia (SCZ), ma…
View article: Aberrant Large-Scale Network Interactions Across Psychiatric Disorders Revealed by Large-Sample Multi-Site Resting-State Functional Magnetic Resonance Imaging Datasets
Aberrant Large-Scale Network Interactions Across Psychiatric Disorders Revealed by Large-Sample Multi-Site Resting-State Functional Magnetic Resonance Imaging Datasets Open
Background and Hypothesis Dynamics of the distributed sets of functionally synchronized brain regions, known as large-scale networks, are essential for the emotional state and cognitive processes. However, few studies were performed to elu…
View article: Development of a classifier for gambling disorder based on functional connections between brain regions
Development of a classifier for gambling disorder based on functional connections between brain regions Open
Aim Recently, a machine‐learning (ML) technique has been used to create generalizable classifiers for psychiatric disorders based on information of functional connections (FCs) between brain regions at resting state. These classifiers pred…
View article: Depressive symptoms reduce when dorsolateral prefrontal cortex-precuneus connectivity normalizes after functional connectivity neurofeedback
Depressive symptoms reduce when dorsolateral prefrontal cortex-precuneus connectivity normalizes after functional connectivity neurofeedback Open
View article: A multi-site, multi-disorder resting-state magnetic resonance image database
A multi-site, multi-disorder resting-state magnetic resonance image database Open
View article: Reduction of brooding and more general depressive symptoms after fMRI neurofeedback targeting a melancholic functional-connectivity biomarker
Reduction of brooding and more general depressive symptoms after fMRI neurofeedback targeting a melancholic functional-connectivity biomarker Open
Depressive disorders contribute heavily to global disease burden; This is possibly because patients are usually treated homogeneously, despite having heterogeneous symptoms with differing underlying neural mechanisms. On the contrary, trea…
View article: Cognition and interpersonal coordination of patients with schizophrenia who have sports habits
Cognition and interpersonal coordination of patients with schizophrenia who have sports habits Open
Team sports activities are effective for improving the negative symptoms and cognitive functions in patients with schizophrenia. However, the interpersonal coordination during the sports and visual cognition of patients with schizophrenia …
View article: Publisher Correction: Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants
Publisher Correction: Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants Open
View article: Early and late effects of electroconvulsive therapy associated with different temporal lobe structures
Early and late effects of electroconvulsive therapy associated with different temporal lobe structures Open
View article: S235. COGNITION AND SOCIAL BEHAVIORS IN SPORTS FOR PATIENTS WITH SCHIZOPHRENIA ENGAGED IN SPORTS HABITS
S235. COGNITION AND SOCIAL BEHAVIORS IN SPORTS FOR PATIENTS WITH SCHIZOPHRENIA ENGAGED IN SPORTS HABITS Open
Background Several studies have reported that team sports are effective for maintaining and improving mental health among patients with schizophrenia. Social behavior, such as adjusting an individual’s motion while reading others’ intentio…
View article: Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants
Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants Open
View article: Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity
Overlapping but Asymmetrical Relationships Between Schizophrenia and Autism Revealed by Brain Connectivity Open
Although the relationship between schizophrenia spectrum disorder (SSD) and autism spectrum disorder (ASD) has long been debated, it has not yet been fully elucidated. The authors quantified and visualized the relationship between ASD and …
View article: Harmonization of resting-state functional MRI data across multiple imaging sites via the separation of site differences into sampling bias and measurement bias
Harmonization of resting-state functional MRI data across multiple imaging sites via the separation of site differences into sampling bias and measurement bias Open
When collecting large amounts of neuroimaging data associated with psychiatric disorders, images must be acquired from multiple sites because of the limited capacity of a single site. However, site differences represent a barrier when acqu…