Explanipedia

Topoisomerase I is an evolutionarily conserved key regulator for satellite DNA transcription Open

Zhen Teng, Lu Yang, Qian Zhang, Yujue Chen, Xianfeng Wang , et al. · 2024

Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription Open

Zhen Teng, Lu Yang, Qian Zhang, Yujue Chen, Xianfeng Wang , et al. · 2024

Repetitive satellite DNAs, divergent in nucleic-acid sequence and size across eukaryotes, provide a physical site for centromere assembly to orchestrate chromosome segregation during the cell cycle. These non-coding DNAs are transcribed by…

A109: A Study of the Relationship Between Exercise Adherence and Depression Open

Yujue Chen, Lei Jun-rong · 2024

Purpose: As the social economy rapidly advances, and competition intensifies, university students are confronted with both increased opportunities and significant psychological pressures. Notably, the incidence of depression is on the rise…

CDK11 facilitates centromeric transcription to maintain centromeric cohesion during mitosis Open

Qian Zhang, Yujue Chen, Zhen Teng, Zhen Lin, Hong Liu · 2023

Actively-transcribing RNA polymerase (RNAP)II is remained on centromeres to maintain centromeric cohesion during mitosis, although it is largely released from chromosome arms. This pool of RNAPII plays an important role in centromere funct…

P658: Hybridization-based target enrichment with Illumina Complete Long-Read assay Open

Tina C. Huang, Tiffany Truong, Yujue Chen, Gary P. Schroth, Feng Chen · 2023

Teaching Platform for Physical Training of Track and Field Events in Colleges and Universities Based on Data Mining Technology Open

Ao Yu, Hyun Choul Cho, Yujue Chen, Xi Chen, Jie Wei , et al. · 2022

To a large extent, track and field sports require strong physical fitness of athletes, and athletes’ physical fitness determines their competition results. With the improvement of people’s living standards, athletes can get better nutritio…

CDK11 Promotes Centromeric Transcription to Maintain Centromeric Cohesion during Mitosis Open

Qian Zhang, Yujue Chen, Zhen Teng, Zhen Lin, Hong Liu · 2022

Actively-transcribing RNA polymerase (RNAP)II is remained on centromeres to maintain centromeric cohesion during mitosis although it is largely released from chromosome arms. This pool of RNAPII plays an important role in centromere functi…

[Retracted] Design and Research of the AI Badminton Model Based on the Deep Learning Neural Network Open

Yujue Chen, He Hu · 2022

In view of the fact that it is difficult for existing algorithms to identify the movements of a player in an accurate way, this paper puts forward an artificial intelligence (AI) motion model on the basis of the deep learning neural networ…

An emerging role of transcription in chromosome segregation: Ongoing centromeric transcription maintains centromeric cohesion Open

Yujue Chen, Qian Zhang, Hong Liu · 2021

Non‐coding centromeres, which dictate kinetochore formation for proper chromosome segregation, are extremely divergent in DNA sequences across species but are under active transcription carried out by RNA polymerase (RNAP) II. The RNAP II‐…

Centromeric transcription maintains centromeric cohesion in human cells Open

Yujue Chen, Qian Zhang, Zhen Teng, Hong Liu · 2021

Centromeric transcription has been shown to play an important role in centromere functions. However, lack of approaches to specifically manipulate centromeric transcription calls into question that the proposed functions are a direct conse…

Multisite phosphorylation determines the formation of Ska–Ndc80 macro-complexes that are essential for chromosome segregation during mitosis Open

Qian Zhang, Liqiao Hu, Yujue Chen, Wei Tian, Hong Liu · 2020

Ska loading to kinetochore is essential for chromosome segregation during mitosis. Here we show that multisite Cdk1 phosphorylation enables the formation of Ska-Ndc80 macro-complexes, thus loading Ska to kinetochores. This process is facil…

SET binding to Sgo1 inhibits Sgo1–cohesin interactions and promotes chromosome segregation Open

Qianhui Qu, Qian Zhang, Lu Yang, Yujue Chen, Hong Liu · 2019

At anaphase onset, Sgo1 function of cohesion protection must be disabled to allow timely chromosome segregation, but how this is achieved is not fully understood. Here, we show that SET, a known PP2A inhibitor, directly binds to a domain i…

Multitasking Ska in Chromosome Segregation: Its Distinct Pools Might Specify Various Functions Open

Qian Zhang, Yujue Chen, Lu Yang, Hong Liu · 2018

The human spindle and kinetochore associated (Ska) complex is required for proper mitotic progression. Extensive studies have demonstrated its important functions in both stable kinetochore‐microtubule interactions and spindle checkpoint s…

Ska3 Phosphorylated by Cdk1 Binds Ndc80 and Recruits Ska to Kinetochores to Promote Mitotic Progression Open

Qian Zhang, Sushama Sivakumar, Yujue Chen, Haishan Gao, Lu Yang , et al. · 2017

Identification of precipitation onset based on Cloudsat observations Open

Yu Wang, Yujue Chen, Yunfei Fu, Guosheng Liu · 2016

Observations of cloud vertical structure by Cloud Profiling Radar on CloudSat satellite provide a unique opportunity to globally identify the onset of precipitation. In this study, based on a conceptual model for an adiabatic cloud, a new …

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