Explanipedia

P11.21.B CLINICAL CHARACTERISTICS AND TREATMENT STRATEGIES FOR CANCER CASES PRESENTING WITH CENTRAL NERVOUS SYSTEM SYMPTOMS AS THE INITIAL MANIFESTATION Open

Nozomi Hirai, Tetsuya Tsukamoto, Munekazu Takeda, Yuki Koyahara, Yuki Hiramoto , et al. · 2025

BACKGROUND Historically, metastatic brain tumors have been associated with a poor prognosis, with median survival reported at approximately six months. Accordingly, brain metastases have often been regarded as a terminal-stage manifestatio…

A case of traumatic intrapleural foreign body with progressive supranuclear palsy removed by thoracoscopic surgery Open

Muneyuki Koyama, Kazuo Matai, Akiyoshi Kinoshita, Shunta Ishizaki, Kouhei Okazaki , et al. · 2023

Transcatheter arterial embolization followed by surgical laparotomy for hemorrhagic shock due to intestinal bleeding: a case report Open

Sayumi Kurita, Kazuo Kitagawa, Naoki Toya, Mutsumi Kaji, Satoshi Yoshioka , et al. · 2022

A Case of Pathological Complete Remission for Colon Cancer with <i>BRAF</i> V600E Mutation and MSI-high Plus Multiple Metastasis by Pembrolizumab after Bevacizumab Plus FOLFOXIRI Therapy Open

Kazuo Kitagawa, Naoto Takahashi, Mutsumi Kaji, Sayumi Kurita, Satoshi Yoshioka , et al. · 2022

【症例】70歳台,女性.【現病歴】上行結腸癌,多発肝転移,肺転移の診断で結腸右半切除術を施行した.病理はpT3pN2b cM1b pStageIVb,RAS野生型,BRAF V600E変異型であった.Bevacizumab+FOLFOXIRI療法を開始したが,Microsatellite instability-high(以下,MSI-H)であったため,Pembrolizumabに変更した.肺転移は消失,肝切除を施行した.病理はpCRで癌細胞は認めなかった.【考察】BRAF…

Segment IV Approach is Useful for Whole-Layer Laparoscopic Cholecystectomy for Gallbladder Polyps Open

Yoshiaki Tanji, Shuichi Fujioka, Hironori Shiozaki, Yuki Takano, Naoto Takahashi , et al. · 2021

Background Whole-layer laparoscopic cholecystectomy (W-LC) has recently been advocated as a total biopsy for potentially malignant neoplasms of the gallbladder; however, it is not an injury-proof procedure. This study reports W-LC using th…

Preoperative Neutrophil–lymphocyte Ratio Is a Predictor of High-output Ileostomy After Colorectal Surgery Open

Yuki Hiramoto, Hidejiro Kawahara, Tomo Matsumoto, Mitsumasa Takeda, Takeyuki Misawa , et al. · 2019

Preoperative NLR seems to be a useful predictor of HOI after colorectal surgery.

Spontaneous Perforation of Sigmoid Colon Due to Chronic Constipation Open

Tomo Matsumoto, Hidejiro Kawahara, Yuki Hiramoto, Mitsumasa Takeda, Takeyuki Misawa and · 2019

Background/Aim: Spontaneous perforation of the sigmoid colon is defined as a sudden perforation of the normal colon in the absence of diseases.However, its etiology remains unclear.Methods: Between January 2010 and December 2017, twenty-th…

Unusual Postoperative Pouch Related Complication in Two Ulcerative Colitis Cases Open

Yuki Hiramoto, Hidejiro Kawahara, Mitsumasa Takeda, Tomo Matsumoto, Takeyuki Misawa , et al. · 2019

A restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has been considered a gold standard surgical procedure for patients with ulcerative colitis (UC).Even if patients with UC underwent high quality IPAA after proctocolect…

Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation Open

Akimasa Seno, Akifumi Mizutani, Kazuki Aizawa, Ryoma Onoue, Junko Masuda , et al. · 2019

Aim: To identify a drug that can effectively eliminate these cancer stem cells (CSCs) and determine its mode of action. Methods: CSCs were obtained from mouse induced pluripotent stem cells (miPSCs) using cancer cell-conditio…

Anthropometric Assessment After Proctocolectomy Due to Ulcerative Colitis Open

Hidejiro Kawahara, Yuki Hiramoto, Mitsumasa Takeda, Nori Matsumoto, Takeyuki Misawa , et al. · 2018

BMI appears to be the most useful predictor of clinical and nutritional changes postoperatively.

Intestinal obstruction caused by primary adenosquamous cell carcinoma of the small intestine: A case report and review of the literature Open

Naotake Funamizu, Yukio Nakabayashi, Katsushi Dairaku, Kenta Tomori, Yuki Hiramoto , et al. · 2018

Primary adenosquamous cell carcinoma (ASCC) arising from the ileum is an exceptionally rare malignant neoplasm exhibiting mixed glandular and squamous differentiation. The clinicopathological characteristics of ASCC have not been clearly d…

Long-term Outcome of Adjuvant Chemotherapy with S-1 Consisting of 3-week Administration Followed by 1-week Rest for Stage III Colorectal Cancer Open

Hidejiro Kawahara, Yuki Hiramoto, Mitsumasa Takeda, Tomo Matusmoto, Takeyuki Misawa , et al. · 2018

Background/Aims: The aim of this study is to evaluate long-term outcome of 3-week method (3-week administration followed by 1-week rest) for colorectal cancer as adjuvant chemotherapy with an oral anticancer drug, S-1.Methods: Between 2008…

Intra-Abdominal Hemorrhage Caused by Ruptured Aneurysm of the Left Gastric Artery : A Case Report (Case Report) Open

Funamizu Naotake, Yukio Nakabayashi, Muneyuki Koyama, Masamichi Momose, Yuki Hiramoto , et al. · 2017

Successful Anal Preservation by Neoadjuvant Imatinib Mesylate Treatment for Resection of Rectal Gastrointestinal Stromal Tumor (GIST): A Case Report Open

Makoto Kosuge, Ken Eto, Ryousuke Hashizume, Mitsumasa Takeda, Yoshiko Uno , et al. · 2016

症例は65歳，女性．検診で便潜血陽性を指摘され，近医で下部消化管内視鏡検査を施行したところ肛門縁近傍の直腸後壁に約３cm大の粘膜下腫瘍を認め当科紹介となった．超音波内視鏡下に穿刺吸引生検を施行しgastrointestinal stromal tumor（GIST）と診断した．根治性を考え腹腔鏡下直腸切断術を提示したが，患者本人の強い肛門温存希望があったため，十分なインフォームドコンセントのもとでメシル酸イマチニブでの術前補助療法を施行した．投与開始後明らかな副作用は認めず…

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