Yuki Kojima
2024
Incidence of skeletal‐related events in patients with Ewing sarcoma: An observational retrospective study in Japan
2024 • Hisaki Aiba, Yuki Kojima, Tatsunori Shimoi, Kazuki Sudo, Shu Yazaki, Toru Imai, Akihiko Yoshida, Shintaro Iwata, Eisuke Kobayashi, Akira Kawai, Ayu...
Exploring foci of
2024-03-01
Incidence of skeletal‐related events in patients with Ewing sarcoma: An observational retrospective study in Japan
2024-03-01 • Hisaki Aiba, Yuki Kojima, Tatsunori Shimoi, Kazuki Sudo, Shu Yazaki, Toru Imai, Akihiko Yoshida, Shintaro Iwata, Eisuke Kobayashi, Akira Kawai, Ayu...
Abstract Background Skeletal‐related events (SREs), including the pathological fracture, surgical treatment or radiation of bone lesions, malignant spinal cord compression, hypercalcemia, are important considerations when managing metastatic bone tumors; however, owing to their rarity, the incidence of SREs in patients with Ewing sarcoma remains unknown. Methods We retrospectively reviewed the clinical data from 146 patients with Ewing sarcoma treated at a single institution from 2005 to 2019. The median age at di…
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Exploring foci of
2024-09-16
Supplementary Table S6 from Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study
2024-09-16 • Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitoshi Ichikawa, Shinji Kohsaka, Ryo Sadachi,...
<p>Targeted sequencing analysis of cell-free DNA samples</p>
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2024-09-16
Supplementary Table S8 from Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study
2024-09-16 • Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitoshi Ichikawa, Shinji Kohsaka, Ryo Sadachi,...
<p>Eligibility and exclusion criteria</p>
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Exploring foci of
2024-09-16
Supplementary Table S3A-B from Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study
2024-09-16 • Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitoshi Ichikawa, Shinji Kohsaka, Ryo Sadachi,...
<p>Pharmacokinetics</p>
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Exploring foci of
2024-09-16
Supplementary Figure S4A from Clinical activity and exploratory resistance mechanism of milademetan, an MDM2 inhibitor, in intimal sarcoma with MDM2 amplification: an open-label phase 1b/2 study
2024-09-16 • Takafumi Koyama, Toshio Shimizu, Yuki Kojima, Kazuki Sudo, Hitomi Sumiyoshi Okuma, Tatsunori Shimoi, Hitoshi Ichikawa, Shinji Kohsaka, Ryo Sadachi,...
<p>Anti-tumor activity</p>
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