Yuki Maki
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View article: Prognostic Impact of Gastrointestinal Immune-Related Adverse Events Depends on Nutritional Status in Cancer Patients Treated with Immune Checkpoint Inhibitors
Prognostic Impact of Gastrointestinal Immune-Related Adverse Events Depends on Nutritional Status in Cancer Patients Treated with Immune Checkpoint Inhibitors Open
Background: Gastrointestinal immune-related adverse events (GI-irAEs) are recognized complications of immune checkpoint inhibitors (ICIs), but their prognostic relevance and associated risk factors remain unclear. This study aimed to asses…
View article: Distinct age-related effects of homologous recombination deficiency on genomic profiling and treatment efficacy in gastric cancer
Distinct age-related effects of homologous recombination deficiency on genomic profiling and treatment efficacy in gastric cancer Open
Background The incidence of gastric cancer among younger patients is increasing globally, with growing attention being paid to the role of homologous recombination deficiency (HRD). However, the effect of HRD on treatment outcomes and prog…
View article: Color density spectral array findings on continuous EEG during therapeutic hypothermia in children with acute encephalopathy
Color density spectral array findings on continuous EEG during therapeutic hypothermia in children with acute encephalopathy Open
This study provides preliminary evidence that reduced HFLs on CDSA predict unfavorable outcomes in AE-affected children undergoing TH. This suggests that maintaining high-frequency waves is critical for optimal brain function.
View article: Reading impairment after neonatal hypoglycemia with parieto-temporo-occipital injury without cortical blindness: A case report
Reading impairment after neonatal hypoglycemia with parieto-temporo-occipital injury without cortical blindness: A case report Open
Patients with perinatal brain injuries in the parietotemporal area require attention and may benefit from additional reading instructions.
View article: Involvement of the Thalamus, Hippocampus, and Brainstem in Hypsarrhythmia of West Syndrome: Simultaneous Recordings of Electroencephalography and fMRI Study
Involvement of the Thalamus, Hippocampus, and Brainstem in Hypsarrhythmia of West Syndrome: Simultaneous Recordings of Electroencephalography and fMRI Study Open
Positive blood oxygen level-dependent responses with hypsarrhythmia appeared in the brainstem, thalamus, and hippocampus on earlier hemodynamic response functions than the cerebral cortices, suggesting the propagation of epileptogenic acti…
View article: Comparison of Clinical Characteristics of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Young Children
Comparison of Clinical Characteristics of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Young Children Open
Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are the leading causes of acute respiratory tract infection in children, and clinical manifestations of these virus infections are considered similar. To investigate the di…
View article: De novo PHACTR1 mutations in West syndrome and their pathophysiological effects
De novo PHACTR1 mutations in West syndrome and their pathophysiological effects Open
Trio-based whole exome sequencing identified two de novo heterozygous missense mutations [c.1449T > C/p.(Leu500Pro) and c.1436A > T/p.(Asn479Ile)] in PHACTR1, encoding a molecule critical for the regulation of protein phosphatase 1 (PP1) a…