Yuki Owada
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Author Swipe
View article: Enhanced Potential of Therapeutic Applications of Curcumin Using Solid-in-Water Nanodispersion Technique
Enhanced Potential of Therapeutic Applications of Curcumin Using Solid-in-Water Nanodispersion Technique Open
Curcumin (Cur), a hydrophobic polyphenol compound, holds promising potential as an anticancer agent. However, the poor solubility in water and the low bioavailability of curcumin have limited its therapeutic applications. In this regard, w…
View article: Quantitative T-cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination
Quantitative T-cell repertoire analysis of peripheral blood mononuclear cells from lung cancer patients following long-term cancer peptide vaccination Open
View article: The efficacy of the Kampo medicine rikkunshito for chemotherapy-induced anorexia (RICH trial): study protocol for a randomized controlled trial
The efficacy of the Kampo medicine rikkunshito for chemotherapy-induced anorexia (RICH trial): study protocol for a randomized controlled trial Open
Japan Pharmaceutical Information Center Clinical Trials Information (JAPIC CTI), trial registration: JAPIC CTI-142747 . Registered on 15 December 2014; the RICH trial.
View article: Epidermal growth factor receptor mutation status is strongly associated with smoking status in patients undergoing surgical resection for lung adenocarcinoma
Epidermal growth factor receptor mutation status is strongly associated with smoking status in patients undergoing surgical resection for lung adenocarcinoma Open
In our cohort of patients who underwent surgical resection for lung adenocarcinoma, EGFR mutation status was strongly associated with smoking status, especially smoking index.
View article: Clinical and pathological aspects of microscopic thymoma with myasthenia gravis and review of published reports
Clinical and pathological aspects of microscopic thymoma with myasthenia gravis and review of published reports Open
Microscopic thymomas tend to be multifocal type A thymomas. Anti-AchR Ab titers decreased significantly in all groups. It is very important to both perform complete extended thymectomies in patients with myasthenia gravis and pathological …
View article: Serum Nitric Oxide as a Predictive Biomarker for Bevacizumab in Non-small Cell Lung Cancer Patients
Serum Nitric Oxide as a Predictive Biomarker for Bevacizumab in Non-small Cell Lung Cancer Patients Open
Serum nitric oxide levels could be a predictive biomarker for response to bevacizumab in NSCLC patients.
View article: Efficacy and tolerability of nanoparticle albumin-bound paclitaxel in combination with carboplatin as a late-phase chemotherapy for recurrent and advanced non-small-cell lung cancer: A multi-center study of the Fukushima lung cancer association group of surgeons
Efficacy and tolerability of nanoparticle albumin-bound paclitaxel in combination with carboplatin as a late-phase chemotherapy for recurrent and advanced non-small-cell lung cancer: A multi-center study of the Fukushima lung cancer association group of surgeons Open
The present retrospective multi-center study aimed to evaluate the efficacy and feasibility of nanoparticle albumin-bound (nab)-paclitaxel plus carboplatin as a second or late-phase chemotherapy in patients with non-small cell lung cancer …
View article: Outcomes after surgical resection of thymic carcinoma
Outcomes after surgical resection of thymic carcinoma Open
View article: FDG-PET in the evaluation of response to nivolumab in recurrent non-small-cell lung cancer
FDG-PET in the evaluation of response to nivolumab in recurrent non-small-cell lung cancer Open
View article: Epidermal growth factor receptor gene mutation as risk factor for recurrence in patients with surgically resected lung adenocarcinoma: a matched-pair analysis
Epidermal growth factor receptor gene mutation as risk factor for recurrence in patients with surgically resected lung adenocarcinoma: a matched-pair analysis Open
EGFR-gene mutation might be a favourable recurrence-risk factor in patients with surgically resected lung ADC, but further studies in larger cohorts are needed to verify this hypothesis.
View article: Revisiting of cancer vaccine?—Specific immunotherapy comes to field with the biomarker
Revisiting of cancer vaccine?—Specific immunotherapy comes to field with the biomarker Open
Coley et al ., advocated a hypothesis of immune response against malignant tumors and he applied his concept by providing patients with the first cancer immunotherapy in 1906 (1). A few decades later, Bacillus Calmette-Guerin was introduce…
View article: Ground-glass nodule in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK)-positive lung cancer: a case report
Ground-glass nodule in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK)-positive lung cancer: a case report Open
View article: Successful Management of Crizotinib-Induced Neutropenia in a Patient with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Case Report
Successful Management of Crizotinib-Induced Neutropenia in a Patient with Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer: A Case Report Open
Crizotinib, the first clinically available inhibitor of anaplastic lymphoma kinase (ALK) gene rearrangement, is generally well tolerated. In contrast, neutropenia induced by crizotinib is a commonly reported grade 3 or 4 adverse event. In …
View article: Development of Novel See-through Head-Mounted Display (ST-HMD) for Medical Clinical Use —Laboratory Experiment Using Central Venous Catheter Insertion Simulator—
Development of Novel See-through Head-Mounted Display (ST-HMD) for Medical Clinical Use —Laboratory Experiment Using Central Venous Catheter Insertion Simulator— Open
View article: Clinical significance of expanded Foxp3+ Helios− regulatory T cells in patients with non-small cell lung cancer
Clinical significance of expanded Foxp3+ Helios− regulatory T cells in patients with non-small cell lung cancer Open
The functions of different regulatory T cell (Treg) types in cancer progression are unclear. Recently, expression of the transcription factor Helios was proposed as a marker for natural (non-induced) Tregs. The present study investigated t…
View article: Examination of resection for pulmonary metastasis of breast cancer
Examination of resection for pulmonary metastasis of breast cancer Open
1978年から2013年に当科で手術を行った乳癌肺転移63例を対象とし，予後因子について統計学的に検討した．単変量解析の結果，予後不良因子は，肺転移最大腫瘍型3 cm以上，ER（estrogen receptor）陰性，乳癌手術時病期StageIII/IV，無病生存期間DFI（desease free interval：乳癌原発巣手術から肺転移手術までの期間）24ヵ月未満，肺手術時の縦隔・肺門部リンパ節転移陽性であった．完全切除と非完全切除例では生存率に有意差は無く手術療法…
View article: A case of anaphylactic shock induced by TachoSil<sup>®</sup> during surgery
A case of anaphylactic shock induced by TachoSil<sup>®</sup> during surgery Open
症例は70代男性．直腸癌，両側転移性肺腫瘍術後経過観察中，右転移性肺腫瘍を疑う結節影が出現し，手術を行った．開胸創を中心に再手術による広範な癒着を認めた．腫瘍摘出後に，剥離の際に生じた気瘻に対し，タコシール®を使用した．貼付約20分後に血圧低下を認めた．エフェドリン，フェニレフリンの効果に乏しく顔面および四肢紅潮を伴い，タコシール®によるアナフィラキシーと判断した．直ちに除去し温生食で洗浄すると，約5分後に血圧は回復した．タコシール®によるアナフィラキシーショックをきたした…
View article: Prognostic Impact of Hypoxia-Inducible<i>miRNA-210</i>in Patients with Lung Adenocarcinoma
Prognostic Impact of Hypoxia-Inducible<i>miRNA-210</i>in Patients with Lung Adenocarcinoma Open
Objective . The aim of this study was to investigate the prognostic value of MicroRNA-210 ( miR-210 ) expression in patients with non-small-cell lung cancer (NSCLC). Methods . We examined the miR-210 expression of samples of 80 patients, w…