Yutong Jiang
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View article: Immunogenicity and safety of co-purified diphtheria, tetanus and acellular pertussis vaccine in 6-year-old Chinese children
Immunogenicity and safety of co-purified diphtheria, tetanus and acellular pertussis vaccine in 6-year-old Chinese children Open
In recent years, China has experienced a rapid increase in the number of pertussis cases among children aged 5 to 9. We conducted this phase 4 randomized, controlled trial (NCT05870631) in Zhejiang Province, China, to compare the immunogen…
View article: A narrative review of the early diagnosis and treatment of idiopathic pulmonary fibrosis with lung cancer
A narrative review of the early diagnosis and treatment of idiopathic pulmonary fibrosis with lung cancer Open
Combining imaging with biomarkers will effectively increase the probability and reliability of early diagnosis of IPF-LC. Antifibrotic drugs not only slow IPF progression, but may also reduce LC risk by inhibiting the pro-fibrotic-cancerou…
View article: PrivWeb: Unobtrusive and Content-aware Privacy Protection For Web Agents
PrivWeb: Unobtrusive and Content-aware Privacy Protection For Web Agents Open
While web agents gained popularity by automating web interactions, their requirement for interface access introduces significant privacy risks that are understudied, particularly from users' perspective. Through a formative study (N=15), w…
View article: Eye‐Drop Nano‐Formulation of Catalase Self‐Assembled with Thiolated Chitosan for Effective Treatment of Dry Eye Disease
Eye‐Drop Nano‐Formulation of Catalase Self‐Assembled with Thiolated Chitosan for Effective Treatment of Dry Eye Disease Open
Dry eye disease (DED), the most prevalent ophthalmological condition worldwide, can cause severe ocular discomfort and even visual impairment. Effective yet safe therapeutics for severe DED are still highly demanded. Herein, considering th…
View article: Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interaction
Mesenchymal stem cell-derived extracellular vesicles alleviate autism by regulating microglial glucose metabolism reprogramming and neuroinflammation through PD-1/PD-L1 interaction Open
Neuroinflammation triggered by microglia activation is hallmark of autism spectrum disorder (ASD), and this process includes crucial metabolic reprogramming from oxidative phosphorylation to glycolysis, which may cause neuron loss and func…
View article: Mapping fatigue: discovering brain regions and genes linked to fatigue susceptibility
Mapping fatigue: discovering brain regions and genes linked to fatigue susceptibility Open
Our findings afford substantial theoretical support for the connection between the brain and fatigue, while also providing novel insights into the genetic mechanisms and therapeutic targets for fatigue, particularly central fatigue.
View article: Predicting higher risk factors for COVID-19 short-term reinfection in patients with rheumatic diseases: a modeling study based on XGBoost algorithm
Predicting higher risk factors for COVID-19 short-term reinfection in patients with rheumatic diseases: a modeling study based on XGBoost algorithm Open
We developed explainable machine learning models to predict the risk of short-term COVID-19 reinfection in patients with rheumatic diseases. SHAP analysis highlighted the importance of clinical and psychological factors. Factors included a…
View article: Causal relationship between ankylosing spondylitis and ocular inflammatory diseases: a Mendelian randomization study
Causal relationship between ankylosing spondylitis and ocular inflammatory diseases: a Mendelian randomization study Open
Background Observational studies have shown an increased risk of ocular inflammatory diseases in patients with ankylosing spondylitis (AS), but the genetically predicted association remains unclear. The aim of this study was to systematica…
View article: Quantum-inspired Beamforming Optimization for Quantized Phase-only Massive MIMO Arrays
Quantum-inspired Beamforming Optimization for Quantized Phase-only Massive MIMO Arrays Open
This paper introduces an innovative quantum-inspired method for beamforming (BF) optimization in multiple-input multiple-output (MIMO) arrays. The method leverages the simulated bifurcation (SB) algorithm to address the complex combinatori…
View article: Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway
Synergistic effect of mesenchymal stem cell-derived extracellular vesicle and miR-137 alleviates autism-like behaviors by modulating the NF-κB pathway Open
Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder predominant in childhood. Despite existing treatments, the benefits are still limited. This study explored the effectiveness of mesenchymal stem cell-derived extr…
View article: Spatial heterogeneity of long-range dependence and self-similarity of global sea surface chlorophyll concentration with their environmental impact factors analysis
Spatial heterogeneity of long-range dependence and self-similarity of global sea surface chlorophyll concentration with their environmental impact factors analysis Open
Understanding the long-range dependence and self-similarity of global sea surface chlorophyll concentration (SSCC) will enrich its characteristics description and analysis with global change patterns. The satellite SSCC products were colle…
View article: Burden of impaired awareness of hypoglycemia in people with diabetes undergoing hemodialysis
Burden of impaired awareness of hypoglycemia in people with diabetes undergoing hemodialysis Open
Introduction Impaired awareness of hypoglycemia (IAH) refers to a diminished capacity to detect hypoglycemia. IAH can result in severe and even life-threatening outcomes for individuals with diabetes, especially those in advanced stages of…
View article: The efficacy of electroacupuncture in the treatment of osteoporotic thoracolumbar compressionfractures in menopausal women:a study protocol for a prospective, two-arm, single-center randomized controlled trial.
The efficacy of electroacupuncture in the treatment of osteoporotic thoracolumbar compressionfractures in menopausal women:a study protocol for a prospective, two-arm, single-center randomized controlled trial. Open
Background Osteoporotic vertebral compression fracture(OVCF) of menopausal women is more prone to result in functional pain, limitations, and significant disability due to lower estrogen levels. Acupuncture therapy is widely used to treat …
View article: Mechanism of <i>Schisandra chinensis</i> in Treatment of Insomnia by Sleep–Wake Cycle Based on Network Pharmacology
Mechanism of <i>Schisandra chinensis</i> in Treatment of Insomnia by Sleep–Wake Cycle Based on Network Pharmacology Open
Background Schisandra chinensis (SC) is the dried fruit of SC of Magnoliaceae, which has been used to treat many diseases, such as asthma, cough, insomnia, spontaneous sweating, and so on, for more than 2000 years. Lignans are important ac…
View article: Macrophage extracellular traps promote tumor-like biologic behaviors of fibroblast-like synoviocytes through cGAS-mediated PI3K/Akt signaling pathway in patients with rheumatoid arthritis
Macrophage extracellular traps promote tumor-like biologic behaviors of fibroblast-like synoviocytes through cGAS-mediated PI3K/Akt signaling pathway in patients with rheumatoid arthritis Open
Rheumatoid arthritis is an autoimmune disease characterized by synovium hyperplasia and bone destruction. Macrophage extracellular traps are released from macrophages under various stimuli and may generate stable autoantigen–DNA complexes,…
View article: AB0010 FERROPTOSIS PROMOTES DYSFUNCTION OF NTREG BUT NOT ITREG IN RHEUMATOID ARTHRITIS
AB0010 FERROPTOSIS PROMOTES DYSFUNCTION OF NTREG BUT NOT ITREG IN RHEUMATOID ARTHRITIS Open
Background Magnetic resonance imaging and histological studies have shown that iron levels are dysregulated in rheumatoid arthritis (RA) patients, with iron accumulation in gray matter and a considerable loss in healthy white matter. Iron …
View article: Application of Synthetic DINCAE–BME Spatiotemporal Interpolation Framework to Reconstruct Chlorophyll–a from Satellite Observations in the Arabian Sea
Application of Synthetic DINCAE–BME Spatiotemporal Interpolation Framework to Reconstruct Chlorophyll–a from Satellite Observations in the Arabian Sea Open
Chlorophyll–a (Chl–a) concentration is an indicator of phytoplankton pigment, which is associated with the health of marine ecosystems. A commonly used method for the determination of Chl–a is satellite remote sensing. However, due to clou…
View article: Asprosin in the Paraventricular Nucleus Induces Sympathetic Activation and Pressor Responses via cAMP-Dependent ROS Production
Asprosin in the Paraventricular Nucleus Induces Sympathetic Activation and Pressor Responses via cAMP-Dependent ROS Production Open
Asprosin is a newly discovered adipokine that is involved in regulating metabolism. Sympathetic overactivity contributes to the pathogenesis of several cardiovascular diseases. The paraventricular nucleus (PVN) of the hypothalamus plays a …
View article: Programmable metasurface RCS prediction under obstacles based on DNN
Programmable metasurface RCS prediction under obstacles based on DNN Open
Programmable metasurfaces have attracted significant attention in various applications such as radar and 6G communications, owing to their ability freely shape the far-field pattern. However, complex calculations and simulations are always…
View article: Parked in the Park: pandemic traffic congestion in Acadia National Park Based on Regression Analysis
Parked in the Park: pandemic traffic congestion in Acadia National Park Based on Regression Analysis Open
Contemporarily, the COVID-19 has strongly affected plenty of fields including travel industry. This paper takes Acadia National Park in the United States as a reference to investigate the impact of the epidemic on the number of visitors to…
View article: Application and Analysis of XCO2 Data from OCO Satellite Using a Synthetic DINEOF–BME Spatiotemporal Interpolation Framework
Application and Analysis of XCO2 Data from OCO Satellite Using a Synthetic DINEOF–BME Spatiotemporal Interpolation Framework Open
Carbon dioxide (CO2) is one of the main greenhouse gases leading to global warming, and the ocean is the largest carbon reservoir on the earth that plays an important role in regulating CO2 concentration on a global scale. The column-avera…
View article: Mechanical Behavior and Microstructure Evolution during High-Temperature Tensile Deformation of MnE21 Magnesium Alloy
Mechanical Behavior and Microstructure Evolution during High-Temperature Tensile Deformation of MnE21 Magnesium Alloy Open
In this study, tensile tests for magnesium–manganese rare earth alloy (MnE21) were conducted with a WDW-300 high-temperature universal testing machine at different temperatures (300 °C~500 °C) and strain rates (1 × 10−4s−1~1 × 10−1s−1). Th…
View article: Coeval Decline of Biological Productivity and Bottom-water Oxygenation in EEP Ocean Recorded by Magnetofossils during the Antarctic Glaciation
Coeval Decline of Biological Productivity and Bottom-water Oxygenation in EEP Ocean Recorded by Magnetofossils during the Antarctic Glaciation Open
The biological pump and deep-ocean ventilation in eastern equatorial Pacific (EEP) Ocean are thought to play a crucial role in cases of global CO2 change. However, the integral role of these two processes in regulating atmospheric CO2 pert…