Yulian Tang
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View article: Mechanistic Research and Therapeutic Advances of the JAK/STAT Signaling Pathway in Myocardial Infarction
Mechanistic Research and Therapeutic Advances of the JAK/STAT Signaling Pathway in Myocardial Infarction Open
Myocardial infarction (MI) is a critical heart disease with high incidence and mortality. Current treatments like coronary reperfusion have limitations, including risks of reperfusion injury and bleeding. Understanding MI's molecular mecha…
View article: PTPRC as a pan-cancer biomarker: Prognostic significance and immune microenvironment interactions
PTPRC as a pan-cancer biomarker: Prognostic significance and immune microenvironment interactions Open
This study investigated the role of Protein Tyrosine Phosphatase Receptor type C (PTPRC) in various cancers using bioinformatics analyses and experimental validation. We analyzed public databases (TIMER2.0, GEPIA2, cBioPortal) and single-c…
View article: Identification of ETV4 as a prognostic biomarker and correlates with immune cell infiltration in head and neck squamous cell carcinoma
Identification of ETV4 as a prognostic biomarker and correlates with immune cell infiltration in head and neck squamous cell carcinoma Open
Head and neck squamous cell carcinoma (HNSC) is a common malignant tumor with high incidence and mortality rates. ETS variant transcription factor 4 (ETV4), an important transcription factor, plays a key role in various cancers. However, t…
View article: Bioinformatics analysis reveals VEGFC’s prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration
Bioinformatics analysis reveals VEGFC’s prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration Open
VEGFC may serve as an independent prognostic factor and potential immunotherapeutic target in HNSCC, offering insights into patient risk stratification and personalized treatment strategies.
View article: Analysis of the Upregulated Expression Mechanism of Apoptotic Chromatin Condensation Inducer 1 in Hepatocellular Carcinoma Based on Bioinformatics
Analysis of the Upregulated Expression Mechanism of Apoptotic Chromatin Condensation Inducer 1 in Hepatocellular Carcinoma Based on Bioinformatics Open
Acin1 is overexpressed in HCC, and the overexpressed Acin1 is most likely regulated by miR-674-5p and other ceRNA molecules.
View article: Peer Review #1 of "Expression, localization, and function of P4HB in the spermatogenesis of Chinese mitten crab (Eriocheir sinensis) (v0.2)"
Peer Review #1 of "Expression, localization, and function of P4HB in the spermatogenesis of Chinese mitten crab (Eriocheir sinensis) (v0.2)" Open
BackgroundThe sperm of Chinese mitten crab (Eriocheir sinensis) have special noncondensed nuclei.The formation and stability of the special nuclei are closely related to the correct folding of proteins during spermatogenesis.P4HB plays a k…
View article: Expression, localization, and function of P4HB in the spermatogenesis of Chinese mitten crab ( <i>Eriocheir sinensis</i> )
Expression, localization, and function of P4HB in the spermatogenesis of Chinese mitten crab ( <i>Eriocheir sinensis</i> ) Open
Background The sperm of Chinese mitten crab ( Eriocheir sinensis ) have special noncondensed nuclei. The formation and stability of the special nuclei are closely related to the correct folding of proteins during spermatogenesis. P4HB play…
View article: HAT1 participates in spermatogenesis of Eriocheir sinensis by regulating chromatin aggregation
HAT1 participates in spermatogenesis of Eriocheir sinensis by regulating chromatin aggregation Open
Chinese mitten crab , Eriocheir sinensis , is a decapod crustacean with a special, non-condensated nucleus in the sperm. Studies has shown that this is closely related to histone modification. To explore the possible role of histone acetyl…
View article: SAP30 targeted by miR-133b was involved in the process of nuclear decondensation in Chinese mitten crab (Eriocheir sinensis) sperm
SAP30 targeted by miR-133b was involved in the process of nuclear decondensation in Chinese mitten crab (Eriocheir sinensis) sperm Open
The aim of this study was to investigate the regulatory role of miR-133b on the expression of Sin3a associated protein 30 (SAP30) during sperm nuclear decondensation. The expressions of both SAP30 at mRNA and protein levels and miRNA targe…
View article: Role of cytoskeleton-related proteins in the acrosome reaction of Eriocheir sinensis spermatozoa
Role of cytoskeleton-related proteins in the acrosome reaction of Eriocheir sinensis spermatozoa Open
View article: RNA binding proteins involved in regulation of protein synthesis to initiate biogenesis of secondary tumor in hepatocellular carcinoma in mice
RNA binding proteins involved in regulation of protein synthesis to initiate biogenesis of secondary tumor in hepatocellular carcinoma in mice Open
Background The tumor microenvironment (TM) in close contact with cancer cells is highly related to tumor growth and cancer metastasis. This study is to explore the biogenesis mechanism of a secondary hepatocellular carcinoma (HCC) based on…