Yu Jiang
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View article: 8277807 The impact of shift work on cognitive impairment in workers and changes in cholinergic-related factor levels
8277807 The impact of shift work on cognitive impairment in workers and changes in cholinergic-related factor levels Open
View article: Wastewater-Based Surveillance of SARS-CoV-2 and Modeling of COVID-19 Infection Trends
Wastewater-Based Surveillance of SARS-CoV-2 and Modeling of COVID-19 Infection Trends Open
Background: This study was performed to evaluate the early warning value of wastewater-based epidemiology (WBE) in monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its correlation with population-level coronaviru…
View article: Prognostic value of combining preoperative immune-inflammatory-nutritional index and tumor biomarkers in gastric cancer patients undergoing radical resection
Prognostic value of combining preoperative immune-inflammatory-nutritional index and tumor biomarkers in gastric cancer patients undergoing radical resection Open
Background Gastric cancer (GC) patients frequently face the debilitating comorbidity of malignant cachexia, a condition that consistently forecasts a dismal prognosis. Early diagnosis of cachexia and timely prediction of survival outcomes …
View article: The Global Regulator VeA Modulates ATP Sulfurylase to Mediate Adenosine Synthesis Resulting in Inhibitory Activity of Endophytic Fusarium solani against A549 Cells
The Global Regulator VeA Modulates ATP Sulfurylase to Mediate Adenosine Synthesis Resulting in Inhibitory Activity of Endophytic Fusarium solani against A549 Cells Open
Adenosine is an endogenous nucleoside that promotes apoptosis in cancer cells. Overexpression of the global regulator VeA gene (FsveA) in Fusarium solani resulted in the accumulation of multiple secondary metabolites, including adenosine. …
View article: Examining the association between tobacco and its substitutes use with psychosocial symptoms among 187,329 adolescents: A comparative analysis across 47 countries with varied universal health coverage index
Examining the association between tobacco and its substitutes use with psychosocial symptoms among 187,329 adolescents: A comparative analysis across 47 countries with varied universal health coverage index Open
Objective: This study aimed to analyze the association between tobacco and its substitutes use and psychosocial symptoms among adolescents, and to investigate whether these associations varied based on the Universal Health Coverage (UHC) i…
View article: The Role and Effectiveness of School Social Workers in Addressing Bullying in China
The Role and Effectiveness of School Social Workers in Addressing Bullying in China Open
The Chinese government has been working hard since 2006 to professionalize and legitimize social work, especially in schools. The occurrence of school bullying and the insufficient reaction from educational institutions and guardians are f…
View article: Exploring the Causal Association between Morning Diurnal Preference and Psychiatric Disorders: A Bidirectional Two-Sample Mendelian Randomization Analysis
Exploring the Causal Association between Morning Diurnal Preference and Psychiatric Disorders: A Bidirectional Two-Sample Mendelian Randomization Analysis Open
Background: The causal connection between morning diurnal preference and psychiatric disorders remains enigmatic. Using bidirectional two-sample Mendelian randomization (MR), we aim to explore the potential causal associations between morn…
View article: The interaction of occupational stress and job burnout on depressive symptoms in railway workers in Fuzhou city
The interaction of occupational stress and job burnout on depressive symptoms in railway workers in Fuzhou city Open
View article: Contribution of sphingomyelin phosphodiesterase acid-like 3B to the proliferation, migration, and invasion of ovarian cancer cells
Contribution of sphingomyelin phosphodiesterase acid-like 3B to the proliferation, migration, and invasion of ovarian cancer cells Open
In summary, this study proposes SMPDL3B as a prognostic marker for ovarian cancer, with implications for potential therapeutic intervention targeting the ACER2-SMPDL3B axis.
View article: Gene‒environment interaction effect of hypothalamic‒pituitary‒adrenal axis gene polymorphisms and job stress on the risk of sleep disturbances
Gene‒environment interaction effect of hypothalamic‒pituitary‒adrenal axis gene polymorphisms and job stress on the risk of sleep disturbances Open
Background Studies have shown that chronic exposure to job stress may increase the risk of sleep disturbances and that hypothalamic‒pituitary‒adrenal (HPA) axis gene polymorphisms may play an important role in the psychopathologic mechanis…
View article: Interactive effects of atmospheric oxidising pollutants and heat waves on the risk of residential mortality
Interactive effects of atmospheric oxidising pollutants and heat waves on the risk of residential mortality Open
Overall, we found some evidence suggesting that heat waves increase the impact of oxidising atmospheric pollutants on residential mortality to some extent.
View article: Artificial light at night and risk of depression: a systematic review and meta-analysis
Artificial light at night and risk of depression: a systematic review and meta-analysis Open
Our findings suggest that both outdoor and indoor ALAN exposures are associated with increased risk of depression. These results underscore the importance of considering outdoor and indoor ALAN in public health strategies aimed at reducing…
View article: The Causal Relationship between the Morning Chronotype and the Gut Microbiota: A Bidirectional Two-Sample Mendelian Randomization Study
The Causal Relationship between the Morning Chronotype and the Gut Microbiota: A Bidirectional Two-Sample Mendelian Randomization Study Open
Background: Numerous observational studies have documented an association between the circadian rhythm and the composition of the gut microbiota. However, the bidirectional causal effect of the morning chronotype on the gut microbiota is u…
View article: Application of machine learning algorithms to construct and validate a prediction model for coronary heart disease risk in patients with periodontitis: a population-based study
Application of machine learning algorithms to construct and validate a prediction model for coronary heart disease risk in patients with periodontitis: a population-based study Open
Background The association between periodontitis and cardiovascular disease is increasingly recognized. In this research, a prediction model utilizing machine learning (ML) was created and verified to evaluate the likelihood of coronary he…
View article: Exploring the Prognosis-Related Genetic Variation in Gastric Cancer Based on mGWAS
Exploring the Prognosis-Related Genetic Variation in Gastric Cancer Based on mGWAS Open
The use of metabolome genome-wide association studies (mGWAS) has been shown to be effective in identifying functional genes in complex diseases. While mGWAS has been applied to biomedical and pharmaceutical studies, its potential in predi…
View article: Prognostic Implication of Plasma Metabolites in Gastric Cancer
Prognostic Implication of Plasma Metabolites in Gastric Cancer Open
Gastric cancer (GC) typically carries a poor prognosis as it is often diagnosed at a late stage. Altered metabolism has been found to impact cancer outcomes and affect patients’ quality of life, and the role of metabolites in gastric cance…
View article: The U-shaped relationship between sleep time on workdays and depression in US aged 20 years and older with hypertension: a cross-sectional study
The U-shaped relationship between sleep time on workdays and depression in US aged 20 years and older with hypertension: a cross-sectional study Open
Background Few epidemiological research has been conducted in hypertensive populations on depression and sleep time on workdays. The aim of our study was to examine the relationship between sleep time on workdays and depression in hyperten…
View article: Development and validation of a depression risk prediction nomogram for US Adults with hypertension, based on NHANES 2007–2018
Development and validation of a depression risk prediction nomogram for US Adults with hypertension, based on NHANES 2007–2018 Open
Depression is of increasing concern as its prevalence increases. Our study’s objective was to create and evaluate a nomogram to predict the likelihood that hypertension patients may experience depression. 13293 people with hypertension who…
View article: Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance
Association of job stress, FK506 binding protein 51 (FKBP5) gene polymorphisms and their interaction with sleep disturbance Open
Background Sleep disturbance is an outcome of multiple factors including environmental and genetic influences. Job stress, a complex environmental factor, likely affects sleep quality, significantly reducing the quality of life of workers.…
View article: A novel prognostic model of gastric cancer patients based on cachexia status by using plasma exosome-derived miRNAs
A novel prognostic model of gastric cancer patients based on cachexia status by using plasma exosome-derived miRNAs Open
Background: Emerging evidence shows that serum biomarkers are closely associated with the prognosis of gastric cancer. Cachexia represents systemic nutritional and metabolic statuses. This study aimed to clinically validate the predictive …
View article: lncRNA polymorphism affects the prognosis of gastric cancer
lncRNA polymorphism affects the prognosis of gastric cancer Open
View article: ML323 suppresses the progression of ovarian cancer via regulating USP1-mediated cell cycle
ML323 suppresses the progression of ovarian cancer via regulating USP1-mediated cell cycle Open
Background: Ubiquitin specific protease 1 (USP1) tightly correlates with poor prognosis of multiple cancers. However, whether USP1 underlies ovarian cancer (OV) progression remains unclarified. Methods: First, GSEA strategy and WGCNA analy…
View article: Efficacy and Side Effects of Irinotecan Combined with Nedaplatin versus Paclitaxel Combined with Cisplatin in Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer and Tumor Marker Analysis: Based on a Retrospective Analysis
Efficacy and Side Effects of Irinotecan Combined with Nedaplatin versus Paclitaxel Combined with Cisplatin in Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer and Tumor Marker Analysis: Based on a Retrospective Analysis Open
Objective. A case-control study was adopted to investigate the efficacy and side effects of irinotecan combined with nedaplatin (NP) versus paclitaxel combined with cisplatin for locally advanced cervical cancer (CC) neoadjuvant chemothera…
View article: LncRNA Polymorphism Affects the Prognosis of Gastric Cancer
LncRNA Polymorphism Affects the Prognosis of Gastric Cancer Open
Background: Previous studies have found that lncRNA polymorphisms are associated with the prognosis of gastric cancer (GC), but the specific roles of many lncRNA polymorphism sites in gastric cancer are still unclear. The aim of our study …
View article: Artificial Intelligence for Image-Based HPV Status Prediction in Head and Neck Cancer: A Systematic Review and Meta-Analysis
Artificial Intelligence for Image-Based HPV Status Prediction in Head and Neck Cancer: A Systematic Review and Meta-Analysis Open
View article: Heparanase/Syndecan-1 Axis Regulates the Grade of Liver Cancer and Proliferative Ability of Hepatocellular Carcinoma Cells
Heparanase/Syndecan-1 Axis Regulates the Grade of Liver Cancer and Proliferative Ability of Hepatocellular Carcinoma Cells Open
Background: Although heparanase/syndecan-1 axis is involved in malignant progression of many cancers, its significance in liver cancer is not well understood. In this study, we explored the value of heparanase/syndecan-1 axis expression in…
View article: mGWAS identification of six novel single nucleotide polymorphism loci with strong correlation to gastric cancer
mGWAS identification of six novel single nucleotide polymorphism loci with strong correlation to gastric cancer Open
View article: ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway
ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway Open
Bladder cancer (BLCA) is the most common malignant tumor of the urinary system, with distant metastasis of the tumor being the main cause of death. The identification of an effective biomarker may provide a novel direction for BLCA diagnos…
View article: [Retracted] MicroRNA‑599 suppresses glioma progression by targeting RAB27B
[Retracted] MicroRNA‑599 suppresses glioma progression by targeting RAB27B Open
Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that certain of the stratch‑wound assay data shown in Fig. 4D were strikingly similar to data appearing in different form in other articl…
View article: A Novel Prognostic Model and Practical Nomogram for Predicting the Outcomes of Colorectal Cancer: Based on Tumor Biomarkers and Log Odds of Positive Lymph Node Scheme
A Novel Prognostic Model and Practical Nomogram for Predicting the Outcomes of Colorectal Cancer: Based on Tumor Biomarkers and Log Odds of Positive Lymph Node Scheme Open
Background Emerging evidence shows that serum tumor biomarkers (TBs) and log odds of positive lymph node scheme (LODDS) are closely associated with the prognosis of colorectal cancer (CRC) patients. The aim of our study is to validate the …