Yuma Osako
YOU?
Author Swipe
View article: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of extra-syn…
View article: Author response: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Author response: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
View article: Reusable modular architecture enables flexible cognitive operations
Reusable modular architecture enables flexible cognitive operations Open
View article: Behavioral expression of decision confidence engages disentangled confidence coding in the orbitofrontal cortex
Behavioral expression of decision confidence engages disentangled confidence coding in the orbitofrontal cortex Open
Task engagement is thought to recruit subsets of neurons encoding task-relevant variables, but it remains unclear whether it also reorganizes the geometry of population codes and how such reorganization supports behavior. Here we show that…
View article: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
Summary Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of e…
View article: Author response: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Author response: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
View article: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
Summary Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of e…
View article: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of extra-syn…
View article: Unraveling the neural code: analysis of large-scale two-photon microscopy data
Unraveling the neural code: analysis of large-scale two-photon microscopy data Open
The brain is an intricate neuronal network that orchestrates our thoughts, emotions and actions through dynamic interactions between neurons. If we could record the activity of all neurons simultaneously in detail, it could revolutionize o…
View article: Reusable Modular Architecture Enables Flexible Cognitive Operations
Reusable Modular Architecture Enables Flexible Cognitive Operations Open
View article: Sensory History Drives Adaptive Neural Geometry in LP/Pulvinar-Prefrontal Cortex Circuits
Sensory History Drives Adaptive Neural Geometry in LP/Pulvinar-Prefrontal Cortex Circuits Open
Summary Prior expectations guide attention and support perceptual filtering for efficient processing during decision-making. Here we show that during a visual discrimination task, mice adaptively use prior stimulus history to guide ongoing…
View article: Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing Open
Astrocytes, which are increasingly recognized as pivotal constituents of brain circuits governing a wide range of functions, express GABA transporter 3 (Gat3), an astrocyte-specific GABA transporter responsible for maintenance of extra-syn…
View article: Cortical norepinephrine-astrocyte signaling critically mediates learned behavior
Cortical norepinephrine-astrocyte signaling critically mediates learned behavior Open
Updating behavior based on feedback from the environment is a crucial means by which organisms learn and develop optimal behavioral strategies 1–3 . Norepinephrine (NE) release from the locus coeruleus (LC) has been shown to mediate learne…
View article: Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cerebral organoids
Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cerebral organoids Open
Summary Human cerebral organoids derived from induced pluripotent stem cells can recapture early developmental processes and reveal changes involving neurodevelopmental disorders. Mutations in the X-linked methyl-CpG binding protein 2 (MEC…
View article: Prefrontal Cortex subregions provide distinct visual and behavioral feedback modulation to the Primary Visual Cortex
Prefrontal Cortex subregions provide distinct visual and behavioral feedback modulation to the Primary Visual Cortex Open
The mammalian Prefrontal Cortex (PFC) has been suggested to modulate sensory information processing across multiple cortical regions via long-range axonal projections. These axonal projections arise from PFC subregions with unique brain-wi…
View article: An intra-oral flavor detection task in freely moving mice
An intra-oral flavor detection task in freely moving mice Open
View article: An intra-oral flavor discrimination task in freely moving mice
An intra-oral flavor discrimination task in freely moving mice Open
Summary Flavor plays a critical role in the pleasure of food. Flavor research has mainly focused on human subjects and revealed that many brain regions are involved in flavor perception. However, animal models for elucidating the mechanism…
View article: Emotional association enhances perceptual memory through amygdalo-cortical inputs during NREM sleep
Emotional association enhances perceptual memory through amygdalo-cortical inputs during NREM sleep Open
Emotional arousal is thought to enhance the consolidation of associated memories by activating the basolateral amygdala (BLA) and its projections to memory-storing regions 1–4 . Although the importance of both rapid eye movement (REM) and …
View article: Auditory Cortex Neurons Show Task-Related and Learning-Dependent Selectivity toward Sensory Input and Reward during the Learning Process of an Associative Memory Task
Auditory Cortex Neurons Show Task-Related and Learning-Dependent Selectivity toward Sensory Input and Reward during the Learning Process of an Associative Memory Task Open
The activity of primary auditory cortex (A1) neurons is modulated not only by sensory inputs but also by other task-related variables in associative learning. However, it is unclear how A1 neural activity changes dynamically in response to…
View article: Reward priming differentially modulates enhancement and inhibition in auditory decision-making
Reward priming differentially modulates enhancement and inhibition in auditory decision-making Open
In cognitive sciences, rewards, such as money and food, play a fundamental role in individuals’ daily lives and well-being. Moreover, rewards that are irrelevant to the task alter individuals’ behavior. However, it is unclear whether expli…
View article: Hippocampal CA1 Neurons Represent Positive Feedback During the Learning Process of an Associative Memory Task
Hippocampal CA1 Neurons Represent Positive Feedback During the Learning Process of an Associative Memory Task Open
The hippocampus is crucial for forming associations between environmental stimuli. However, it is unclear how neural activities of hippocampal neurons dynamically change during the learning process. To address this question, we developed a…
View article: Over-representation of fundamental decision variables in the prefrontal cortex underlies decision bias
Over-representation of fundamental decision variables in the prefrontal cortex underlies decision bias Open
The brain is organized into anatomically distinct structures consisting of a variety of projection neurons. While such evolutionarily conserved neural circuit organization underlies the innate ability of animals to swiftly adapt to environ…
View article: Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat
Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat Open
It is widely assumed that trial-by-trial variability in visual detection performance is explained by the fidelity of visual responses in visual cortical areas influenced by fluctuations of internal states, such as vigilance and behavioral …
View article: Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat. Y.Osako et al., 2021
Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat. Y.Osako et al., 2021 Open
Dataset analyzed and produced in "Contribution of non-sensory neurons in visual cortical areas to visually guided decisions in the rat" by Osako et al., (2021).
View article: Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs
Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs Open
View article: Visually-evoked choice behavior driven by distinct population computations with non-sensory neurons in visual cortical areas
Visually-evoked choice behavior driven by distinct population computations with non-sensory neurons in visual cortical areas Open
It is widely assumed that variability in visual detection performance is attributed to the fidelity of the visual responses in visual cortical areas, which could be modulated by fluctuations of internal states such as vigilance and behavio…
View article: Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs
Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs Open
Dataset of Ohnuki et al., 2020
View article: Visually Guided Decisions Driven by Distinct Population Computations with Non-Sensory Neurons in Visual Cortical Areas
Visually Guided Decisions Driven by Distinct Population Computations with Non-Sensory Neurons in Visual Cortical Areas Open
View article: Activities of the perirhinal cortical neurons analyzed at single-neuron and population levels
Activities of the perirhinal cortical neurons analyzed at single-neuron and population levels Open
Dataset analyzed and produced in "Dynamic coordination of the perirhinal cortical neurons supports coherent representations between task epochs" by Ohnuki et al., (2020).
View article: Effects of subjective visibility on our cognitive function: How visual attentional modulation correlates with subjective visibility
Effects of subjective visibility on our cognitive function: How visual attentional modulation correlates with subjective visibility Open