Yumei Tao
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View article: Regulation of alternative splicing of retinol metabolism in lipid abnormality of PCOS liver by Cyp4a32 and Hsd17b6
Regulation of alternative splicing of retinol metabolism in lipid abnormality of PCOS liver by Cyp4a32 and Hsd17b6 Open
Liver lipid disorders are common in polycystic ovary syndrome (PCOS) patients. A DHEA-induced PCOS mouse model exhibited elevated liver triglyceride (TG) and total cholesterol (TC), reinforcing this association between liver lipids and PCO…
View article: Tumor necrosis factor promotes doublecortin-like kinase 1 expression and cellular reprogramming in intestinal epithelial cells leading to neoplastic transformation
Tumor necrosis factor promotes doublecortin-like kinase 1 expression and cellular reprogramming in intestinal epithelial cells leading to neoplastic transformation Open
View article: Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock
Melatonin refines ovarian mitochondrial dysfunction in PCOS by regulating the circadian rhythm gene Clock Open
Mitochondrial dysfunction is present in the ovaries of patients with polycystic ovary syndrome (PCOS). Melatonin (MT) has shown promise in treating PCOS by improving mitochondrial dysfunction, though the underlying mechanisms remain unclea…
View article: Inactivation of glutathione <i>S</i> -transferase alpha 4 blocks <i>Enterococcus faecalis</i> -induced bystander effect by promoting macrophage ferroptosis
Inactivation of glutathione <i>S</i> -transferase alpha 4 blocks <i>Enterococcus faecalis</i> -induced bystander effect by promoting macrophage ferroptosis Open
Enterococcus faecalis-infected macrophages produce 4-hydroxynonenal (4-HNE) that mediates microbiota-induced bystander effect (MIBE) leading to colorectal cancer (CRC). Glutathione S-transferase alpha 4 (Gsta4), a specific de…
View article: Colonic expression of glutathione S-transferase alpha 4 and 4-hydroxynonenal adducts is correlated with the pathology of murine colitis-associated cancer
Colonic expression of glutathione S-transferase alpha 4 and 4-hydroxynonenal adducts is correlated with the pathology of murine colitis-associated cancer Open
Chronic inflammation-induced oxidative stress is an important driving force for developing colitis-associated cancer (CAC). 4-hydroxynonenal (4-HNE) is a highly reactive aldehyde derived from lipid peroxidation of ω-6 polyunsaturated fatty…
View article: Loss of expression of protein tyrosine kinase 7 in invasive ductal breast cancers.
Loss of expression of protein tyrosine kinase 7 in invasive ductal breast cancers. Open
Protein tyrosine kinase 7 (PTK7) is a catalytically inactive receptor tyrosine kinase that is involved in development and tumorigenesis. PTK7 expression and its functional roles have been investigated in several human cancers, although con…
View article: Downregulation of SASH1 correlates with tumor progression and poor prognosis in ovarian carcinoma
Downregulation of SASH1 correlates with tumor progression and poor prognosis in ovarian carcinoma Open
SAM- and SH3-domain containing 1 (SASH1) is a recently identified tumor suppressor gene that is required in the tumorigenesis of breast and other solid carcinomas. The SASH1 protein contains SH3 and SAM domains, indicating that it may serv…
View article: BRCA2 N372H Polymorphism and Risk of Epithelial Ovarian Cancer
BRCA2 N372H Polymorphism and Risk of Epithelial Ovarian Cancer Open
The BRCA2 N372H is the only common polymorphism that leads to the amino acid change based on the reports up to date. Previous studies explored the relationship between the single nucleotide polymorphism and ovarian cancer risk, but the res…
View article: Vascular endothelial growth factor affects dendritic cell activity in hypertensive disorders of pregnancy
Vascular endothelial growth factor affects dendritic cell activity in hypertensive disorders of pregnancy Open
Vascular endothelial growth factor (VEGF) activity is involved in the growth and stability of the placenta, and its signaling has been implicated in the development of pregnancy‑induced hypertension (PIH). The present study sought to evalu…