Yumei Zhang
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View article: Preliminary experience of lenvatinib, tislelizumab and transcatheter arterial chemoembolization for BCLC stage C hepatocellular carcinoma: a phase II study
Preliminary experience of lenvatinib, tislelizumab and transcatheter arterial chemoembolization for BCLC stage C hepatocellular carcinoma: a phase II study Open
ClinicalTrials.gov identifier: NCT05131698, registered 4 November 2021.
View article: Characteristics and prognosis of language impairment in subcortical aphasia of acute stroke patients
Characteristics and prognosis of language impairment in subcortical aphasia of acute stroke patients Open
Background Subcortical aphasia, caused by lesions in deep brain structures such as the basal ganglia, thalamus, and periventricular white matter, remains poorly understood due to its heterogeneous clinical presentations and disputed neural…
View article: Factors Associated with Anthropometry Z-Scores in Exclusively Breastfed Infants Aged 0–6 Months in 10 Cities of China
Factors Associated with Anthropometry Z-Scores in Exclusively Breastfed Infants Aged 0–6 Months in 10 Cities of China Open
Objectives: The present study evaluated anthropometry Z-scores of exclusively breastfed infants aged 0~6 months and examined their associations with various parent–infant factors. Methods: This cross-sectional study included 383 mother–inf…
View article: Safety and Tolerance of Bifidobacterium longum subsp. Infantis YLGB-1496 in Toddlers with Respiratory Symptoms
Safety and Tolerance of Bifidobacterium longum subsp. Infantis YLGB-1496 in Toddlers with Respiratory Symptoms Open
Objective: The aim of this study was to examine the safety and tolerance of Bifidobacterium longum subsp. infantis YLGB-1496 (B. infantis YLGB-1496) in toddlers with respiratory illness. Methods: In this randomized controlled trial, 120 to…
View article: Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion
Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion Open
View article: Molecular Mechanisms of Chinese Medicine in Regulating Colorectal Cancer Immune Microenvironment: Insights from Single-Cell Transcriptomics and Network Pharmacology
Molecular Mechanisms of Chinese Medicine in Regulating Colorectal Cancer Immune Microenvironment: Insights from Single-Cell Transcriptomics and Network Pharmacology Open
Background The molecular mechanisms underlying the efficacy of Traditional Chinese Medicine (TCM) in colorectal cancer treatment remain largely unexplored. We developed a computational systems biology approach integrating single-cell trans…
View article: Clinical effects of Bifidobacterium Longum Subsp. Infantis YLGB-1496 on children with respiratory symptoms
Clinical effects of Bifidobacterium Longum Subsp. Infantis YLGB-1496 on children with respiratory symptoms Open
Objectives This study aimed to examine the effects of Bifidobacterium longum subsp. infantis YLGB-1496 ( B. infantis YLGB-1496) on the frequency of respiratory illness symptoms and immunity profiles among toddlers. Methods In this double-b…
View article: Clinical and Metabolic Responses to Diacylglycerol Oil Administration In Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
Clinical and Metabolic Responses to Diacylglycerol Oil Administration In Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial Open
View article: Indication and Timing of Tracheotomy in Burn Patients
Indication and Timing of Tracheotomy in Burn Patients Open
View article: Relationship between thyroid-stimulating hormone and blood lipids in patients with first-episode depression
Relationship between thyroid-stimulating hormone and blood lipids in patients with first-episode depression Open
TSH was highly correlated with abnormal lipid metabolism in patients with MDD. The specific molecular mechanism of the relationship between TSH, lipid metabolism and the development of depression needs to be further in-depth investigation.
View article: Maternal BMI During Lactation Is Associated with Major Protein Compositions in Early Mature Milk
Maternal BMI During Lactation Is Associated with Major Protein Compositions in Early Mature Milk Open
Objectives: The present study identified multiple proteins in early mature milk and explored the correlation between protein compositions in HM and maternal BMI during lactation. Methods: A total of 70 mothers giving birth to single-term i…
View article: Exploration of potential antidiabetic and antioxidant components from the branches of Mitragyna diversifolia and possible mechanism
Exploration of potential antidiabetic and antioxidant components from the branches of Mitragyna diversifolia and possible mechanism Open
In this study, sixteen compounds were isolated from the branches of Mitragyna diversifolia, including twelve triterpenes (1-12), a phenolic compound (13), and three flavonoids (14-16). Among them, compounds 1-7, and 10-16 were reported for…
View article: An aptamer‐guided fluorescence polarisation platform for extracellular vesicle liquid biopsy
An aptamer‐guided fluorescence polarisation platform for extracellular vesicle liquid biopsy Open
The translation of discoveries on extracellular vesicle (EV) based cancer biomarkers to personalised precision oncology requires the development of robust, sensitive and specific assays that are amenable to adoption in the clinical laborat…
View article: K2CO3-catalyzed highly efficient O and N-acylation under mild conditions
K2CO3-catalyzed highly efficient O and N-acylation under mild conditions Open
An eco-friendly, mild and efficient acylation of various nucleophiles with alkenyl carboxylates via inorganic base catalysis is described. Among five inorganic base species examined, K2CO3 was proved to be the most efficient catalyst for t…
View article: Patterns of Human Milk Oligosaccharides in Mature Milk Are Associated with Certain Gut Microbiota in Infants
Patterns of Human Milk Oligosaccharides in Mature Milk Are Associated with Certain Gut Microbiota in Infants Open
Human milk oligosaccharides (HMOs) are complexes that play a crucial role in shaping the early-life gut microbiota. This study intends to explore whether HMO patterns are associated with the gut microbiota of infants. We included 96 Chines…
View article: Nano implant surface triggers autophagy through membrane curvature distortion to regulate the osteogenic differentiation
Nano implant surface triggers autophagy through membrane curvature distortion to regulate the osteogenic differentiation Open
Anodized titania nanotubes have been considered as an effective coating for bone implants due to their ability to induce osteogenesis, whereas the osteogenic mechanism is not fully understood. Our previous study has revealed the potential …
View article: The Effect of Sn-2 Palmitate on Blood Glucose, Lipids and Body Composition in Middle-Aged and Elderly Adults: A Randomized, Double-Blinded Controlled Trial
The Effect of Sn-2 Palmitate on Blood Glucose, Lipids and Body Composition in Middle-Aged and Elderly Adults: A Randomized, Double-Blinded Controlled Trial Open
Sn-2 palmitate is widely used in infant formula. However, little is known about its effects on metabolism and body composition in middle-aged and elderly adults. In a double-blinded, randomized controlled trial, we enrolled Chinese adults …
View article: Metabolomic Investigation of Brain and Liver in Rats Fed Docosahexaenoic Acid in Regio‐ and Enantiopure Triacylglycerols
Metabolomic Investigation of Brain and Liver in Rats Fed Docosahexaenoic Acid in Regio‐ and Enantiopure Triacylglycerols Open
Scope N‐3 polyunsaturated fatty acids (n‐3 PUFAs) play important roles in cognitive functions. However, there is a lack of knowledge on the metabolic impact of regio‐ and stereo‐specific positioning of n‐3 PUFAs in dietary triacylglycerols…
View article: Influence of Dietary Triacylglycerol Structure on the Accumulation of Docosahexaenoic Acid [22:6(n‐3)] in Organs in a Short‐Term Feeding Trial with Mildly Omega‐3 Deficient Rats
Influence of Dietary Triacylglycerol Structure on the Accumulation of Docosahexaenoic Acid [22:6(n‐3)] in Organs in a Short‐Term Feeding Trial with Mildly Omega‐3 Deficient Rats Open
Scope To study the effect of positional distribution of docosahexaenoic acid (DHA) in dietary triacylglycerols (TAG) on the tissue fatty acid content and composition of mildly (n‐3) deficient rats. Methods and results In a 5‐day feeding tr…
View article: The clinical characteristics, gene mutations and outcomes of myelodysplastic syndromes with diabetes mellitus
The clinical characteristics, gene mutations and outcomes of myelodysplastic syndromes with diabetes mellitus Open
Purpose Diabetes mellitus (DM) is the second most common comorbidity in myelodysplastic syndromes (MDS). The purpose of the study was to investigate the clinical characteristics of MDS patients with DM. Methods A retrospective analysis was…
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View article: Integrating GWAS and Genomic Selection to Enhance Soybean Breeding
Integrating GWAS and Genomic Selection to Enhance Soybean Breeding Open
View article: Association between CT-based adipose variables, preoperative blood biochemical indicators and pathological T stage of clear cell renal cell carcinoma
Association between CT-based adipose variables, preoperative blood biochemical indicators and pathological T stage of clear cell renal cell carcinoma Open
Preoperative PLT, FIB and TAM are nonlinearly related to pathological T stage. This study is the first to provide specific cut-off intervals for preoperative variables that are nonlinearly related to ccRCC T stage. These intervals can aid …
View article: Efficacy and Safety of Bifidobacterium longum Supplementation in Infants: A Meta-Analysis of Randomized Controlled Trials
Efficacy and Safety of Bifidobacterium longum Supplementation in Infants: A Meta-Analysis of Randomized Controlled Trials Open
Background: Strategies to stabilize and support overall infant health by increasing the number of Bifidobacterium longum in the infant gut are of interest, but few studies have systematically addressed this issue. We aimed to evaluate the …
View article: Roles of vitamin K‑dependent protein in biomineralization (Review)
Roles of vitamin K‑dependent protein in biomineralization (Review) Open
Vitamin K (VK), a fat‑soluble vitamin, is well known as an anticoagulant in the clinic. It is essential for the post‑translational activation of VK‑dependent proteins (VKDPs) because hydroquinone VK is a cofactor of glutamine carboxylase. …
View article: A bibliometric analysis of research foci and trends in cerebral ischemia-reperfusion injury involving autophagy during 2008 to 2022
A bibliometric analysis of research foci and trends in cerebral ischemia-reperfusion injury involving autophagy during 2008 to 2022 Open
Background: Cerebral ischemia-reperfusion injury (CIRI) is a complex pathophysiological process that typically occurs during the treatment of ischemia, with limited therapeutic options. Autophagy plays a vital role during the reperfusion p…
View article: A preliminary study on the occupational performances in immersive virtual and real environments in stroke patients
A preliminary study on the occupational performances in immersive virtual and real environments in stroke patients Open
Instrumental activities of daily living (IADL) training is critical in clinical practice of occupational therapy (OT) for stroke patients. In the conventional approaches, the therapists simulate various occupational tasks in their healthca…
View article: Prediction of Fuhrman nuclear grade for clear cell renal carcinoma by a multi-information fusion model that incorporates CT-based features of tumor and serum tumor associated material
Prediction of Fuhrman nuclear grade for clear cell renal carcinoma by a multi-information fusion model that incorporates CT-based features of tumor and serum tumor associated material Open
View article: Correction: Kulkarni et al. Tissue-Specific Content of Polyunsaturated Fatty Acids in (n-3) Deficiency State of Rats. Foods 2021, 11, 208
Correction: Kulkarni et al. Tissue-Specific Content of Polyunsaturated Fatty Acids in (n-3) Deficiency State of Rats. Foods 2021, 11, 208 Open
The authors would like to make the following corrections to a published paper [...]
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