Yumiko Kono
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View article: MRI outperforms CT for tracheal and vascular invasion staging in esophageal cancer
MRI outperforms CT for tracheal and vascular invasion staging in esophageal cancer Open
Objectives To validate a standardized MRI scoring system, tracheal invasion score (T-score) and vascular invasion score (V-score) against CT for detecting tracheal and major-vessel invasion in esophageal cancer, based on imaging obtained a…
View article: Prognostic value of whole-body diffusion-weighted imaging with background body signal suppression in CRPC patients undergoing Ra-223 therapy: an exploratory analysis
Prognostic value of whole-body diffusion-weighted imaging with background body signal suppression in CRPC patients undergoing Ra-223 therapy: an exploratory analysis Open
Objectives The aim of this study was to evaluate the utility of diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) in monitoring the response to Ra-223 therapy in patients with castration-resistant prosta…
View article: Evaluation of 177Lu-Labeled Lipiodol as a Targeted Radionuclide Therapy for Hepatocellular Carcinoma in a Preclinical Xenograft Model
Evaluation of 177Lu-Labeled Lipiodol as a Targeted Radionuclide Therapy for Hepatocellular Carcinoma in a Preclinical Xenograft Model Open
Background Lutetium-177 ( 177 Lu) is a promising radionuclide for targeted cancer therapy due to its favorable theranostic properties. Transarterial lipiodol embolization is widely used for hepatocellular carcinoma (HCC), but the potential…
View article: Diagnostic Dilemma of Rounded Atelectasis in the Left Lower Lobe Showing High Uptake of 18F-Fluorodeoxyglucose: A Surgical Conundrum
Diagnostic Dilemma of Rounded Atelectasis in the Left Lower Lobe Showing High Uptake of 18F-Fluorodeoxyglucose: A Surgical Conundrum Open
Differentiating rounded atelectasis from lung cancer can be challenging. Rounded atelectasis has a low-to-moderate maximum standardized uptake value of 18F-fluorodeoxyglucose (18F-FDG); however, some cases show high u…
View article: The utility of dwibs in surveillance after treatment of head and neck cancer
The utility of dwibs in surveillance after treatment of head and neck cancer Open
View article: Correction: Development and Validation of a Preoperative Nomogram for Endoscopic Management Decision Making in Upper Urinary Tract Urothelial Carcinoma
Correction: Development and Validation of a Preoperative Nomogram for Endoscopic Management Decision Making in Upper Urinary Tract Urothelial Carcinoma Open
View article: Challenges of “Young Carer Support” in Japan and Role of Community-based Integrated Support Centers
Challenges of “Young Carer Support” in Japan and Role of Community-based Integrated Support Centers Open
To clarify the challenges of young carer support among professionals engaged in community-based integrated care in the eastern area of Shizuoka Prefecture, Japan, as a basis for determining the role of community-based integrated support ce…
View article: Assessing Therapeutic Response to Radium-223 with an Automated Bone Scan Index among Metastatic Castration-Resistant Prostate Cancer Patients: Data from Patients in the J-RAP-BSI Trial
Assessing Therapeutic Response to Radium-223 with an Automated Bone Scan Index among Metastatic Castration-Resistant Prostate Cancer Patients: Data from Patients in the J-RAP-BSI Trial Open
To evaluate the usefulness of change in the automated bone scan index (aBSI) value derived from bone scintigraphy findings as an imaging biomarker for the assessment of treatment response and survival prediction in metastatic castration-re…
View article: Two cases of <scp>18F‐FDG‐PET</scp> / <scp>CT</scp> positive Schloffer tumor following curative surgery of colon cancer
Two cases of <span>18F‐FDG‐PET</span> / <span>CT</span> positive Schloffer tumor following curative surgery of colon cancer Open
We report two cases of Schloffer tumor that required resection after radical colon cancer surgery because of suspected lymph node recurrence on contrast‐enhanced (CE) CT and 18F‐FDG‐PET/CT. Case1 is a 69‐year‐old man with sigmoid colon can…
View article: Carcinoma of Unknown Original Identified as Renal Cell Carcinoma by 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan: A Report of Two Cases
Carcinoma of Unknown Original Identified as Renal Cell Carcinoma by 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan: A Report of Two Cases Open
Imaging is useful in identifying the primary site of an unknown primary cancer, and 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is an excellent imaging modality for identif…
View article: Novel nomogram developed for determining suitability of metastatic castration resistant prostate cancer patients to receive maximum benefit from radium-223 dichloride treatment – Japanese Ra-223 Therapy in Prostate Cancer using Bone Scan Index (J-RAP-BSI) Trial
Novel nomogram developed for determining suitability of metastatic castration resistant prostate cancer patients to receive maximum benefit from radium-223 dichloride treatment – Japanese Ra-223 Therapy in Prostate Cancer using Bone Scan Index (J-RAP-BSI) Trial Open
Purpose: To develop a novel nomogram for determining radium-223 dichloride (Ra-223) treatment suitability for metastatic castration resistant prostate cancer (mCRPC) patients. Methods: This Japanese Ra-223 Therapy in Prostate Cancer using …
View article: Efficacy of Combination Therapy with Lenvatinib and Radioactive Iodine in Thyroid Cancer Preclinical Model
Efficacy of Combination Therapy with Lenvatinib and Radioactive Iodine in Thyroid Cancer Preclinical Model Open
Patients with differentiated thyroid cancer (DTC) usually have good prognosis, while those with advanced disease have poor clinical outcomes. This study aimed to investigate the antitumor effects of combination therapy with lenvatinib and …
View article: Table of Contents
Table of Contents Open
View article: Potential of combination therapy with lenvatinib and radiation for thyroid cancer
Potential of combination therapy with lenvatinib and radiation for thyroid cancer Open
分化型甲状腺癌は一般に予後良好であるが,進行癌ではしばしば局所再発や遠隔転移をきたし予後不良である.切除不能の進行分化型甲状腺癌の治療としては放射性ヨウ素(131I)内用療法,およびチロシンキナーゼ阻害剤が主であるが,前者は131I治療抵抗例が多く,後者は有害事象の発生率が高いことが問題となる.そこで我々は分化型甲状腺癌細胞とxenograftモデルマウスを用いて分子標的薬レンバチニブと放射線外照射の併用による相乗効果を検討した.レンバチニブと放射線外照射の併用療法は,in…
View article: Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume
Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume Open
View article: A comparison of HER2/neu accumulations of Ga-67-labeled anti-HER2 antibody with chemically and site-specifically conjugated bifunctional chelators
A comparison of HER2/neu accumulations of Ga-67-labeled anti-HER2 antibody with chemically and site-specifically conjugated bifunctional chelators Open
View article: Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume
Impact of four-dimensional cone-beam computed tomography on target localization for gastric mucosa-associated lymphoid tissue lymphoma radiotherapy: reducing planning target volume Open
Background: Radiotherapy of gastric mucosa-associated lymphoid tissue (MALT) lymphoma should be delivered to the entire stomach with planning target volume (PTV) that accounts for variations in stomach volume, respiratory movement, and pat…
View article: Impact of Four-Dimensional Cone-Beam Computed Tomography on Target Localization for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Radiotherapy: Reducing Planning Target Volume Margin
Impact of Four-Dimensional Cone-Beam Computed Tomography on Target Localization for Gastric Mucosa-Associated Lymphoid Tissue Lymphoma Radiotherapy: Reducing Planning Target Volume Margin Open
Background: Radiotherapy of gastric mucosa-associated lymphoid tissue (MALT) lymphoma should be delivered to the whole stomach with optimal planning target volume (PTV) margins that account for variations in stomach volume, respiratory mov…
View article: A comparison of HER2 tumor accumulations of Ga-67 labeled anti-HER2 antibody with chemically and site-specifically conjugated bifunctional chelators
A comparison of HER2 tumor accumulations of Ga-67 labeled anti-HER2 antibody with chemically and site-specifically conjugated bifunctional chelators Open
Background Monoclonal antibodies (mAb) developed to target specific cancers have achieved considerable success to-date. To further enhance therapeutic efficacy monoclonal antibodies may be conjugated with a cytotoxic drug or radioisotope. …
View article: A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model
A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model Open
Airway hyperresponsiveness (AHR) has been proposed as a feature of pathogenesis of eosinophilic upper airway inflammation such as allergic rhinitis (AR). The measurement system for upper AHR (UAHR) in rodents is poorly developed, although …
View article: Involvement of latent TGF-beta binding protein 4 (LTBP-4) and Fibulin-5 in age-associated changes in aortic morphology and function
Involvement of latent TGF-beta binding protein 4 (LTBP-4) and Fibulin-5 in age-associated changes in aortic morphology and function Open
Extracellular matrix (ECM), mainly composed of elastin and collagens, is a fundamental structural component participating in vascular function. Previously, our group demonstrated that LTBP-4 and Fibulin-5 are key molecules in regulating el…
View article: Dementia care based on hospital size : An internet-based survey of nurse experience
Dementia care based on hospital size : An internet-based survey of nurse experience Open
The aims of this study were to examine variations in dementia care based on hospital size and to identify opportunities for improvement of care level.We conducted a large-scale survey of nurses focusing on 1) the comparison of dementia car…
View article: The effects of irradiation on multidrug resistance in a non-small lung cancer cell line
The effects of irradiation on multidrug resistance in a non-small lung cancer cell line Open
がんにおける多剤耐性能（Multi-drug resistance; MDR）は化学療法の治療効果を減弱させる機序として知られているが放射線照射ががん細胞のMDRにどう影響するかは明らかにされていない．核医学診断薬であるTc-99m methoxyisobutylisonitrile （MIBI） はMDRの主要因である細胞膜に存在するMDR関連ATP-binding cassette （ABC） transporterを介しdoxorubicinやcisplatinなどの…
View article: The effect of radiation exposure on multidrug resistance: in vitro and in vivo studies using non-small lung cancer cells
The effect of radiation exposure on multidrug resistance: in vitro and in vivo studies using non-small lung cancer cells Open
Irradiation decreased MDR in NSCLC cells. In combination with a low-dose MDR modulator, GG918, MDR transport function was synergistically reduced 48 h post-irradiation.
View article: Evaluation of standardized uptake values in PET normalized using a predictive equation for lean body mass
Evaluation of standardized uptake values in PET normalized using a predictive equation for lean body mass Open
Poster: ECR 2015 / C-0441 / Evaluation of standardized uptake values in PET normalized using a predictive equation for lean body mass by: Y. Kono, K. Utsunomiya, K. Nakano, N. Tanigawa; Osaka/JP
View article: Evaluation of an aspiration-type semiautomatic cutting biopsy needle
Evaluation of an aspiration-type semiautomatic cutting biopsy needle Open