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View article: Author Correction: Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways
Author Correction: Aldolase B suppresses hepatocellular carcinogenesis by inhibiting G6PD and pentose phosphate pathways Open
View article: Comparative Analysis of the Uterine Microbiome in Canine Pyometra: A 16S rRNA Sequencing Study
Comparative Analysis of the Uterine Microbiome in Canine Pyometra: A 16S rRNA Sequencing Study Open
Canine pyometra is a prevalent reproductive disorder predominantly affecting older, nulliparous bitches, with peak incidence during the diestrus phase. This condition is frequently complicated by systemic infections and carries high mortal…
View article: P2RX4 promotes hepatocellular carcinoma progression via calcium-mediated PI3K/AKT activation and immune remodeling
P2RX4 promotes hepatocellular carcinoma progression via calcium-mediated PI3K/AKT activation and immune remodeling Open
View article: Glyphosate exposure impairs visual function in zebrafish larvae through retinoic acid-dependent regulation of six3b expression
Glyphosate exposure impairs visual function in zebrafish larvae through retinoic acid-dependent regulation of six3b expression Open
Glyphosate (GLY) is a widely used, broad-spectrum organophosphorus herbicide. Epidemiological studies have raised concerns about its potential risks due to environmental residues and occupational exposure, yet the molecular mechanisms unde…
View article: Combined predictive model for prostate cancer screening: Development and validation study
Combined predictive model for prostate cancer screening: Development and validation study Open
View article: Cholecystitis and cholangiocarcinoma: a two-sample Mendelian randomization study
Cholecystitis and cholangiocarcinoma: a two-sample Mendelian randomization study Open
We found evidence supporting a causal effect between cholecystitis and cholangiocarcinoma, indicating an increased likelihood of cholangiocarcinoma in patients with cholecystitis through MR analysis.These findings may help inform clinical …
View article: The expression of transmembrane channel-like 5 in gastric cancer and its impact on tumor progression
The expression of transmembrane channel-like 5 in gastric cancer and its impact on tumor progression Open
View article: The clinical outcomes of lamellar keratomileusis in patients with human immunodeficiency virus positivity
The clinical outcomes of lamellar keratomileusis in patients with human immunodeficiency virus positivity Open
View article: Graph Federated Learning for Personalized Privacy Recommendation
Graph Federated Learning for Personalized Privacy Recommendation Open
Federated recommendation systems (FedRecs) have gained significant attention for providing privacy-preserving recommendation services. However, existing FedRecs assume that all users have the same requirements for privacy protection, i.e.,…
View article: Update on the global, regional, and national burden of pancreatic cancer: Insights from the Global Burden of Disease 2021 Study
Update on the global, regional, and national burden of pancreatic cancer: Insights from the Global Burden of Disease 2021 Study Open
View article: Comparative efficacy of holmium laser versus plasma techniques in the surgical management of non-muscle invasive bladder cancer: a meta-analysis
Comparative efficacy of holmium laser versus plasma techniques in the surgical management of non-muscle invasive bladder cancer: a meta-analysis Open
Background This systematic review and meta-analysis compared the efficacy of Holmium Laser and Plasma Techniques in treating non-muscle invasive bladder cancer (NMIBC), focusing on surgical duration, safety, and tumor recurrence. Methods A…
View article: Uptakes of boronophenylalanine in the in vitro and in situ glioblastoma and the potential efficacy of boron neutron capture therapy
Uptakes of boronophenylalanine in the in vitro and in situ glioblastoma and the potential efficacy of boron neutron capture therapy Open
View article: Application and perspectives of nanomaterials in boron neutron capture therapy of tumors
Application and perspectives of nanomaterials in boron neutron capture therapy of tumors Open
Boron neutron capture therapy (BNCT) is a two-step targeted radiotherapy technique, which selectively delivers 10B atoms to tumor tissues, leading to selective tumor destruction through thermal neutron irradiation. BNCT, which utilizes bor…
View article: Integrated multi-omics reveals terpenoid-driven metabolic and transcriptional regulation underlying sweetpotato resistance to black spot disease
Integrated multi-omics reveals terpenoid-driven metabolic and transcriptional regulation underlying sweetpotato resistance to black spot disease Open
Sweetpotato black spot disease, caused by the fungus Ceratocystis fimbriata, is known to have a detrimental impact on both crop yield and postharvest quality. This research employed a combination of transcriptomic and metabolomic analyses …
View article: Long-term remission of microsatellite instability-high adenosquamous carcinoma in gastric antrum: a case report
Long-term remission of microsatellite instability-high adenosquamous carcinoma in gastric antrum: a case report Open
Background Gastric adenosquamous carcinoma (ASC) is an exceedingly rare neoplasm. Its infrequent occurrence has resulted in sparse literature on its diagnosis and management, presenting considerable challenges for clinical practice. Case p…
View article: A review of osteoporotic vertebral fracture animal models
A review of osteoporotic vertebral fracture animal models Open
Introduction Osteoporotic vertebral fractures are a common outcome of osteoporosis, imposing a substantial economic burden. The development of reliable animal models is essential for advancing research. This review examines osteoporotic ve…
View article: LEMMA: Learning from Errors for MatheMatical Advancement in LLMs
LEMMA: Learning from Errors for MatheMatical Advancement in LLMs Open
Large language models (LLMs) have demonstrated remarkable reasoning capability in solving mathematical problems. However, existing approaches primarily focus on improving the quality of correct training data, e.g., distilling high-quality …
View article: The impact of the pandemic on non-COVID-19 causes of death in the United States: a multiple cause of death analysis
The impact of the pandemic on non-COVID-19 causes of death in the United States: a multiple cause of death analysis Open
Multiple cause of death data allow for a more granular analysis of the pandemic’s impact on mortality from non-COVID-19 causes of death compared with analysis of a single underlying cause of each death because they are often a co-morbidity…
View article: ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation
ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation Open
Background Integrin Subunit Alpha 4 (ITGA4), a member of the integrin protein family, is involved in the progression of malignant tumors. However, its role across different cancer types is not well understood. Methods Utilizing multi-omics…
View article: Anion gap predicting 90-Day mortality and guiding furosemide use in ARDS
Anion gap predicting 90-Day mortality and guiding furosemide use in ARDS Open
The objective of this study was to investigate whether serum anion gap (AG), which may serve as an indicator for multiple organic dysfunctions in the condition of hypoxia, could be utilized as a reliable prognostic marker for short-term mo…
View article: Effects of rumen fluid transplantation on the fecal flora of yaks
Effects of rumen fluid transplantation on the fecal flora of yaks Open
Introduction There are few studies on the effect of rumen fluid transplantation on the fecal flora of yaks. Yak fecal flora is closely related to their health. This study aimed to evaluate the effects of rumen fluid transplantation on grow…
View article: Analysis of BGN and pan-cancer correlations: based a Mendelian randomisation and bioinformatics study
Analysis of BGN and pan-cancer correlations: based a Mendelian randomisation and bioinformatics study Open
Background/Objectives: To preliminarily explore the significance of BGN in various cancers using pan-cancer analysis. Methods: Transcriptome data of 33 cancers were downloaded from TCGA database, and the expression levels of BGN in 33 canc…
View article: Environmental factors inducing gastric cancer: insights into risk and prevention strategies
Environmental factors inducing gastric cancer: insights into risk and prevention strategies Open
View article: The dual role of gut microbiota in pancreatic cancer: new insights into onset and treatment
The dual role of gut microbiota in pancreatic cancer: new insights into onset and treatment Open
Pancreatic cancer ranks among the most lethal digestive malignancies, exhibiting a steadily increasing incidence and mortality worldwide. Despite significant advances in cancer research, the 5-year survival rate remains below 10%, predomin…
View article: Fully Endoscopic Microvascular Decompression in Primary Hemifacial Spasm: Technical Note and Clinical Outcomes
Fully Endoscopic Microvascular Decompression in Primary Hemifacial Spasm: Technical Note and Clinical Outcomes Open
View article: LEMMA: Learning from Errors for MatheMatical Advancement in LLMs
LEMMA: Learning from Errors for MatheMatical Advancement in LLMs Open
View article: A dual-signal-amplified electrochemical biosensor for sensitive and accurate detection of cancer cells
A dual-signal-amplified electrochemical biosensor for sensitive and accurate detection of cancer cells Open
The crucial role of HRP in catalyzing the redox reaction between Fe(CN) 6 3− and H 2 O 2 is highlighted, with the resulting detectable current signals being linked to the quantity of captured target cancer cells.
View article: CT-based delta-radiomics for predicting pathological response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a multicenter study
CT-based delta-radiomics for predicting pathological response to neoadjuvant immunochemotherapy in esophageal squamous cell carcinoma: a multicenter study Open
The delta-radiomics model exhibited better diagnostic performance in preoperative prediction of pCR for NICT in ESCC patients compared to the clinical, pre-treatment radiomics, and mixed models.
View article: A CLOSER LOOK AT EMOTIONAL ACCEPTANCE IN LATE LIFE
A CLOSER LOOK AT EMOTIONAL ACCEPTANCE IN LATE LIFE Open
When older adults regulate emotions, they tend to prefer emotional acceptance (i.e., embracing emotions without judging them) over other strategies, such as reappraisal (i.e., reframing an emotional situation to view it in a more positive …
View article: Integrin α2 in the microenvironment and the tumor compartment of digestive (gastrointestinal) cancers: emerging regulators and therapeutic opportunities
Integrin α2 in the microenvironment and the tumor compartment of digestive (gastrointestinal) cancers: emerging regulators and therapeutic opportunities Open
Integrins are a family of cell surface membrane receptors and play a crucial role in facilitating bidirectional cell signaling. Integrin α2 (ITGA2) is expressed across a range of cell types, including epithelial cells, platelets, megakaryo…