Ting‐Yun Lin
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View article: High interindividual variability of indoxyl sulfate production identified by an oral tryptophan challenge test
High interindividual variability of indoxyl sulfate production identified by an oral tryptophan challenge test Open
View article: Association of the oral microbiome with cognitive function among older adults: NHANES 2011–2012
Association of the oral microbiome with cognitive function among older adults: NHANES 2011–2012 Open
Oral microbial composition was associated with executive function and subjective memory changes among older adults among older U.S. adults in a nationally representative population sample. Oral dysbiosis is a potential biomarker or therape…
View article: #1172 Identification of phenyl sulfate producer phenotypes by an oral tyrosine challenge test: a microbiota-based personalized nutritional approach
#1172 Identification of phenyl sulfate producer phenotypes by an oral tyrosine challenge test: a microbiota-based personalized nutritional approach Open
Background and Aims Phenyl sulfate (PS) has been implicated in the pathogenesis of diabetic kidney disease (DKD). PS is converted from phenol, a gut microbial metabolite of dietary tyrosine, and sulfated into PS by aryl sulfotransferases i…
View article: Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study
Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study Open
Aim: The first coronavirus disease 2019 (COVID-19) outbreak in Taiwan occurred in May 2021 and many individuals were infected. All COVID-19 patients were quarantined in designated facilities until they fully recovered to prevent the spread…
View article: Corrected QT Interval and Outcomes of Dialysis Patients with Symptomatic Peripheral Artery Disease: A Prospective Cohort Study
Corrected QT Interval and Outcomes of Dialysis Patients with Symptomatic Peripheral Artery Disease: A Prospective Cohort Study Open
Background: Peripheral artery disease (PAD) is common and associated with a higher risk of cardiovascular morbidity and mortality in dialysis patients. A longer corrected QT (QTc) interval has been associated with adverse cardiovascular ev…
View article: Humoral immune response to an mRNA-1273 booster after chAdOx1-nCoV-19-priming among patients undergoing hemodialysis
Humoral immune response to an mRNA-1273 booster after chAdOx1-nCoV-19-priming among patients undergoing hemodialysis Open
A BSTRACT Objectives: Patients who are undergoing dialysis due to end-stage kidney disease are susceptible to greater coronavirus disease 2019 (COVID-19) complications. While vaccination is seen as the most effective tactic against COVID-1…
View article: Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management Open
View article: Anti-Inflammatory and Anti-Oxidative Effects of Polysaccharides Extracted from Unripe Carica papaya L. Fruit
Anti-Inflammatory and Anti-Oxidative Effects of Polysaccharides Extracted from Unripe Carica papaya L. Fruit Open
This study evaluated the antioxidative and anti-inflammatory activities of polysaccharides extracted from unripe Carica papaya L. (papaya) fruit. Three papaya polysaccharide (PP) fractions, namely PP-1, PP-2, and PP-3, with molecular weigh…
View article: #4843 EFFECT OF MORNING VACCINATION COMPARED WITH AFTERNOON/EVENING VACCINATION ON HUMORAL RESPONSE TO COVID-19 VACCINE IN HEMODIALYSIS PATIENTS
#4843 EFFECT OF MORNING VACCINATION COMPARED WITH AFTERNOON/EVENING VACCINATION ON HUMORAL RESPONSE TO COVID-19 VACCINE IN HEMODIALYSIS PATIENTS Open
Background and Aims Patients with ESKD who are undergoing hemodialysis have impaired immunogenicity to SARS-CoV-2 vaccination. Age, dialysis vintage, use of immunosuppressive drugs, serum albumin, lymphocyte count, vaccine type, and COVID-…
View article: #5285 SERUM IRON AND NUTRITIONAL STATUS ARE ASSOCIATED IN PATIENTS WITH CHRONIC KIDNEY DISEASE
#5285 SERUM IRON AND NUTRITIONAL STATUS ARE ASSOCIATED IN PATIENTS WITH CHRONIC KIDNEY DISEASE Open
Background and Aims Both anemia and malnutrition are highly prevalent in patients with chronic kidney disease (CKD). Iron deficiency plays a significant role in anemia of CKD. However, whether iron deficiency contributes to malnutrition in…
View article: Morning Vaccination Compared with Afternoon/Evening Vaccination on Humoral Response to SARS-CoV-2 Adenovirus Vector-Based Vaccine in Hemodialysis Patients
Morning Vaccination Compared with Afternoon/Evening Vaccination on Humoral Response to SARS-CoV-2 Adenovirus Vector-Based Vaccine in Hemodialysis Patients Open
Division of Nephrology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, and School of Medicine, Tzu Chi University, Hualien, Taiwan Correspondence: Dr. Szu-Chun Hung, Division of Nephrology, Taipei Tzu Chi Hospital, 289, Jian…
View article: Association of malnutrition with SARS-CoV-2 vaccine response in patients undergoing hemodialysis
Association of malnutrition with SARS-CoV-2 vaccine response in patients undergoing hemodialysis Open
View article: Using a Short Food Frequency Questionnaire to Evaluate Macronutrients, Fiber, Phosphorus, Potassium, and Calcium in Adults with Stages 3–5 Chronic Kidney Disease
Using a Short Food Frequency Questionnaire to Evaluate Macronutrients, Fiber, Phosphorus, Potassium, and Calcium in Adults with Stages 3–5 Chronic Kidney Disease Open
The progression of chronic kidney disease (CKD) can be directly or indirectly accelerated by a poor diet and the diet’s influence on risk factors for this disease. There have been no food frequency questionnaires (FFQs) developed for the a…
View article: Periureteral Liposarcoma Causes of Hydroureter and Hydronephrosis
Periureteral Liposarcoma Causes of Hydroureter and Hydronephrosis Open
When obstructive lesions from the uterus or ovaries are suspected, patients with hydronephrosis are usually referred to a gynecologist. Here, a case of suspected endometriosis-related hydroureteronephrosis is reported. A 43-year-old woman …
View article: Association of Reactogenicity with Immunogenicity of the ChAdOx1 nCoV-19 Vaccine in Patients Undergoing Hemodialysis
Association of Reactogenicity with Immunogenicity of the ChAdOx1 nCoV-19 Vaccine in Patients Undergoing Hemodialysis Open
The aim of our study was to determine whether local and systemic reactions following SARS-CoV-2 vaccination are predictive of immunogenicity in patients undergoing hemodialysis. We used an established questionnaire to survey 206 hemodialys…
View article: Association of secondary prevention medication use after myocardial infarction with mortality in hemodialysis patients
Association of secondary prevention medication use after myocardial infarction with mortality in hemodialysis patients Open
Background Mortality after myocardial infarction (MI) among patients undergoing dialysis is high. However, studies investigating the use of secondary prevention medications after MI and clinical outcomes in dialysis patients are lacking. T…
View article: Aging is associated with slower renal progression in patients with chronic kidney disease
Aging is associated with slower renal progression in patients with chronic kidney disease Open
Objectives: Chronic kidney disease (CKD) is prevalent among the elderly. However, little is known about how the clinical course of CKD vary with age. The purpose of this study was to examine the impact of aging on the risk of end-stage kid…
View article: Effect of Pholiota nameko Polysaccharides Inhibiting Methylglyoxal-Induced Glycation Damage In Vitro
Effect of Pholiota nameko Polysaccharides Inhibiting Methylglyoxal-Induced Glycation Damage In Vitro Open
Advanced glycation end products (AGEs) can induce oxidative stress and inflammation. AGEs are major risk factors for the development of many aging-related diseases, such as cancer and diabetes. In this study, Pholiota nameko polysaccharide…
View article: Nephroprotective Role of Chrysophanol in Hypoxia/Reoxygenation-Induced Renal Cell Damage via Apoptosis, ER Stress, and Ferroptosis
Nephroprotective Role of Chrysophanol in Hypoxia/Reoxygenation-Induced Renal Cell Damage via Apoptosis, ER Stress, and Ferroptosis Open
Acute kidney injury (AKI) is caused by hypoxia-reoxygenation (H/R), which is a kidney injury produced by a variety of causes, resulting in the remaining portion of the kidney function being unable to maintain the balance for performing the…
View article: MO137DIFFERENCES IN GUT MICROBIOTA PROFILES AND FUNCTIONS BETWEEN END-STAGE KIDNEY DISEASE AND HEALTHY POPULATIONS
MO137DIFFERENCES IN GUT MICROBIOTA PROFILES AND FUNCTIONS BETWEEN END-STAGE KIDNEY DISEASE AND HEALTHY POPULATIONS Open
Background and Aims Patients with end-stage kidney disease (ESKD) are characterized by altered gut microbiota, impaired intestinal barrier function, and experienced gut microbiota-derived metabolites related to systemic complications. Howe…
View article: MO603PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF MALNUTRITION IN DIALYSIS PATIENTS UNDERGOING ENDOVASCULAR THERAPY FOR PERIPHERAL ARTERY DISEASE
MO603PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF MALNUTRITION IN DIALYSIS PATIENTS UNDERGOING ENDOVASCULAR THERAPY FOR PERIPHERAL ARTERY DISEASE Open
Background and Aims Malnutrition often coexists with inflammation and atherosclerosis and is associated with adverse clinical outcomes in dialysis patients. However, both prevalence and prognostic significance of preexisting malnutrition i…
View article: Differences in the Microbial Composition of Hemodialysis Patients Treated with and without β-Blockers
Differences in the Microbial Composition of Hemodialysis Patients Treated with and without β-Blockers Open
β-blockers are commonly prescribed to treat cardiovascular disease in hemodialysis patients. Beyond the pharmacological effects, β-blockers have potential impacts on gut microbiota, but no study has investigated the effect in hemodialysis …
View article: Gut dysbiosis and mortality in hemodialysis patients
Gut dysbiosis and mortality in hemodialysis patients Open
View article: Anti-Acid Drug Treatment Induces Changes in the Gut Microbiome Composition of Hemodialysis Patients
Anti-Acid Drug Treatment Induces Changes in the Gut Microbiome Composition of Hemodialysis Patients Open
Anti-acid drugs, proton pump inhibitor (PPI) and histamine-2 blocker (H2-blocker), are commonly prescribed to treat gastrointestinal disorders. These anti-acid drugs alter gut microbiota in the general population, but their effects are not…
View article: Loss of Function of von Hippel‐Lindau Trigger Lipocalin 2‐Dependent Inflammatory Responses in Cultured and Primary Renal Tubular Cells
Loss of Function of von Hippel‐Lindau Trigger Lipocalin 2‐Dependent Inflammatory Responses in Cultured and Primary Renal Tubular Cells Open
Previous studies have shown that mutations in the tumor suppressor gene von Hippel‐Lindau ( VHL ) can result in the overproduction of reactive oxygen species (ROS) and chronic inflammation and are a significant predisposing factor for the …
View article: Comparative Gut Microbiome Differences between Ferric Citrate and Calcium Carbonate Phosphate Binders in Patients with End-Stage Kidney Disease
Comparative Gut Microbiome Differences between Ferric Citrate and Calcium Carbonate Phosphate Binders in Patients with End-Stage Kidney Disease Open
Gut dysbiosis in patients with chronic kidney disease (CKD) may induce chronic inflammation and increase morbidity. Phosphate-binding agents, generally used in patients with CKD, may potentially change the composition of the gut microbiota…
View article: Indoxyl Sulfate and Incident Peripheral Artery Disease in Hemodialysis Patients
Indoxyl Sulfate and Incident Peripheral Artery Disease in Hemodialysis Patients Open
Peripheral artery disease (PAD) is highly prevalent among patients with chronic kidney disease (CKD) and portends a very poor prognosis. Indoxyl sulfate has been shown to induce atherothrombosis and impaired neovascularization in uremic mi…
View article: Differences in Gut Microbiota Profiles and Functions Between End-stage Renal Disease and Healthy Populations 
Differences in Gut Microbiota Profiles and Functions Between End-stage Renal Disease and Healthy Populations Open
Background: Patients with end-stage renal disease (ESRD) have extremely high risks of mortality and morbidity, as well as altered gut microbiota and impaired intestinal barrier function. The translocation of gut-derived molecules in ESRD c…
View article: Differences in the Microbial Composition of Hemodialysis Patients Treated With and Without β-Blockers
Differences in the Microbial Composition of Hemodialysis Patients Treated With and Without β-Blockers Open
Background: β-blockers are commonly prescribed medications to treat cardiovascular disease and prevent sudden cardiac death during hemodialysis. Beyond the medication effects on the host, no study has investigated the impact of β-blocker o…
View article: MO043IDENTIFICATION OF INDOXYL SULFATE PRODUCER PHENOTYPES BY ORAL TRYPTOPHAN CHALLENGE TEST: A MICROBIOTA-BASED PERSONALIZED NUTRITIONAL APPROACH
MO043IDENTIFICATION OF INDOXYL SULFATE PRODUCER PHENOTYPES BY ORAL TRYPTOPHAN CHALLENGE TEST: A MICROBIOTA-BASED PERSONALIZED NUTRITIONAL APPROACH Open
Background and Aims Indoxyl sulfate (IS), one of the most representative gut-derived uremic toxins, has been implicated in the pathogenesis of cardiovascular disease in patients with chronic kidney disease (CKD). However, current approache…