Y. Wang
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View article: Identification of PIWI-interacting RNAs based models for lung adenocarcinoma early detection: a multicenter cohort study
Identification of PIWI-interacting RNAs based models for lung adenocarcinoma early detection: a multicenter cohort study Open
Early detection of lung adenocarcinoma (LUAD) remains a major clinical challenge despite the widespread application of low-dose computed tomography (LDCT). Circulating PIWI-interacting RNAs (piRNAs), characterized by tumor-specific express…
View article: Body mass index and risk of post-induction hypotension in older adults undergoing non-cardiac surgery: a retrospective cohort study
Body mass index and risk of post-induction hypotension in older adults undergoing non-cardiac surgery: a retrospective cohort study Open
View article: Phytoconstituents, antioxidant and enzyme inhibition activities of coffee beans through widely targeted metabolomes and in vitro arrays
Phytoconstituents, antioxidant and enzyme inhibition activities of coffee beans through widely targeted metabolomes and in vitro arrays Open
Coffee has transcended from a beverage into a functional food, with its efficacy heavily influenced by germplasm diversity. We systematically analyzed 37 coffee accessions, revealing substantial diversity in morphological characteristics, …
View article: Effects and potential mechanisms of the ultra-high dose rate radiotherapy on lung injury: a review
Effects and potential mechanisms of the ultra-high dose rate radiotherapy on lung injury: a review Open
Ultra-high dose rate (FLASH) radiotherapy is a novel modality delivering dose rates several orders of magnitude higher than conventional dose rate (CONV) radiotherapy. FLASH radiotherapy has been shown to significantly reduce the damaging …
View article: Isolation of acephate-degrading bacteria and phytoremediation–microbial remediation from soil for the project of water diversion from the Yangtze River to Chaohu Lake
Isolation of acephate-degrading bacteria and phytoremediation–microbial remediation from soil for the project of water diversion from the Yangtze River to Chaohu Lake Open
Introduction Efficient and safe governance of soil contaminated with organophosphate pesticides is of crucial significance for the protection of the ecosystem. This study focuses on soils from typical riparian zones along the project of wa…
View article: RWD188 ADOPTION AND CHALLENGES OF ELECTRONIC CLINICAL OUTCOME ASSESSMENTS AND PATIENT-REPORTED OUTCOMES IN CHINA: INSIGHTS FROM A SURVEY OF HEALTHCARE PROFESSIONALS AND INDUSTRY STAKEHOLDERS
RWD188 ADOPTION AND CHALLENGES OF ELECTRONIC CLINICAL OUTCOME ASSESSMENTS AND PATIENT-REPORTED OUTCOMES IN CHINA: INSIGHTS FROM A SURVEY OF HEALTHCARE PROFESSIONALS AND INDUSTRY STAKEHOLDERS Open
View article: Potential effect of FLASH radiotherapy on testicular damage: a review of current evidence
Potential effect of FLASH radiotherapy on testicular damage: a review of current evidence Open
Radiotherapy is a major source of ionizing radiation that adversely affects the male reproductive system. FLASH radiotherapy (FLASH-RT), a novel technique delivering ultra-high dose rate (UHDR) radiation, has shown promise in reducing norm…
View article: Complement Overactivation as a Causal Driver of Sepsis-Associated Coagulopathy: A Mendelian Randomization Study from the UK Biobank
Complement Overactivation as a Causal Driver of Sepsis-Associated Coagulopathy: A Mendelian Randomization Study from the UK Biobank Open
Background This study aimed to investigate the causal relationship between complement system overactivation and coagulopathy in sepsis using a two-sample Mendelian Randomization (MR) approach. Methods We conducted genome-wide association s…
View article: 589 | THE EFFICACY AND SAFETY OF ORELABRUTINIB‐BASED REGIMENS IN THE TREATMENT OF MARGINAL ZONE LYMPHOMA: A RETROSPECTIVE REAL‐WORLD STUDY
589 | THE EFFICACY AND SAFETY OF ORELABRUTINIB‐BASED REGIMENS IN THE TREATMENT OF MARGINAL ZONE LYMPHOMA: A RETROSPECTIVE REAL‐WORLD STUDY Open
View article: Laparoscopic Myomectomy: Morcellator Dangers and Leiomyomatosis Leritonealis Disseminata
Laparoscopic Myomectomy: Morcellator Dangers and Leiomyomatosis Leritonealis Disseminata Open
View article: The effect of diverse sports skills interventions on physical fitness and brain development among Chinese high school students: a cluster randomized controlled trial study protocol
The effect of diverse sports skills interventions on physical fitness and brain development among Chinese high school students: a cluster randomized controlled trial study protocol Open
The study was registered at the China Clinical Trial Registry (ChiCTR2300070942). https://www.chictr.org.cn . Registered on April 10, 2023.
View article: Prediction of STAS in lung adenocarcinoma with nodules ≤ 2 cm using machine learning: a multicenter retrospective study
Prediction of STAS in lung adenocarcinoma with nodules ≤ 2 cm using machine learning: a multicenter retrospective study Open
View article: Dupilumab, corticosteroids and their combination for the treatment of bullous pemphigoid
Dupilumab, corticosteroids and their combination for the treatment of bullous pemphigoid Open
For BP patients, dupilumab monotherapy based on the treatment of atopic dermatitis can significantly improve skin lesions and pruritus symptoms but may be ineffective for oral mucosal lesions. The combination of dupilumab and medium/low-do…
View article: Construction of a neutrophil extracellular trap formation-related gene model for predicting the survival of lung adenocarcinoma patients and their response to immunotherapy
Construction of a neutrophil extracellular trap formation-related gene model for predicting the survival of lung adenocarcinoma patients and their response to immunotherapy Open
We developed a novel prognostic signature for LUAD patients based on NFRGs and emphasized the critical role of this signature in predicting LUAD patient survival and immunotherapy response.
View article: New Insights into Human Dermal Microvasculature: A Study Based on Intravascular Perfusion and Immunofluorescence Staining
New Insights into Human Dermal Microvasculature: A Study Based on Intravascular Perfusion and Immunofluorescence Staining Open
Skin microcirculation offers critical insights into systemic health and disease mechanisms. Despite this importance, specific characteristics and distribution patterns of dermal microarterioles and microvenules have been insufficiently exp…
View article: Clinical and immunoserological characteristics of anti‐p200 pemphigoid: Comparisons of patients with epitope spreading and non‐epitope spreading
Clinical and immunoserological characteristics of anti‐p200 pemphigoid: Comparisons of patients with epitope spreading and non‐epitope spreading Open
Background Anti‐p200 pemphigoid is a rare autoimmune subepidermal blistering disease. Although the phenomenon of epitope spreading has been reported to be common in anti‐p200 pemphigoid, the association between its clinical and immunoserol…
View article: ACE Gene Mutations (rs577350502) in Early-Onset and Recurrent Myocardial Infarction: A Case Report and Review
ACE Gene Mutations (rs577350502) in Early-Onset and Recurrent Myocardial Infarction: A Case Report and Review Open
While this variant has not been previously reported to be associated with any specific disease, we hypothesize that it may contribute to the susceptibility and risk of myocardial infarction and coronary heart disease in the patient under c…
View article: Laparoscopic sacrocolpopexy for treatment of pelvic organ prolapse, a prospective observation cohort with follow-up time over 7 years
Laparoscopic sacrocolpopexy for treatment of pelvic organ prolapse, a prospective observation cohort with follow-up time over 7 years Open
To the Editor: Pelvic organ prolapse (POP) is a common pelvic floor disorder in older women and is responsible for a significant decrease in health-related quality of life. With the increased longevity and demographic of older women, POP i…
View article: Factors Affecting Intention to Leave Among ICU Healthcare Professionals in China: Insights from a Cross-Sectional Survey and XGBoost Analysis
Factors Affecting Intention to Leave Among ICU Healthcare Professionals in China: Insights from a Cross-Sectional Survey and XGBoost Analysis Open
Satisfaction with income was found to be the strongest predictor of intention to leave among ICU healthcare professionals. Additionally, factors such as years of experience, night shift frequency, and pride in hospital work were found to p…
View article: Sporadic lymphangioleiomyomatosis in a man with somatic mosaicism of <i>TSC2</i> mutations, a case report
Sporadic lymphangioleiomyomatosis in a man with somatic mosaicism of <i>TSC2</i> mutations, a case report Open
View article: An ICD-Associated DAMP Gene signature predicts survival and immunotherapy response of patients with lung adenocarcinoma
An ICD-Associated DAMP Gene signature predicts survival and immunotherapy response of patients with lung adenocarcinoma Open
Background While some lung adenocarcinoma (LUAD) patients benefit long-term from treatment with immune checkpoint inhibitors, the sad reality is that a considerable proportion of patients do not. The classification of the LUAD tumor microe…
View article: 1006P RANKL drives malignant phenotypes and poor prognosis in KRAS-mutated lung adenocarcinoma
1006P RANKL drives malignant phenotypes and poor prognosis in KRAS-mutated lung adenocarcinoma Open
View article: CCDC 2155415: Experimental Crystal Structure Determination
CCDC 2155415: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Safety, pharmacokinetics, and efficacy of BPI-15086 in patients with EGFR T790M-mutated advanced non-small-cell lung cancer: results from a phase I, single-arm, multicenter study
Safety, pharmacokinetics, and efficacy of BPI-15086 in patients with EGFR T790M-mutated advanced non-small-cell lung cancer: results from a phase I, single-arm, multicenter study Open
View article: CCDC 2043654: Experimental Crystal Structure Determination
CCDC 2043654: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1889776: Experimental Crystal Structure Determination
CCDC 1889776: Experimental Crystal Structure Determination Open
View article: MA08.09 Clinical Management of Lung Adenocarcinoma Patients With HER2 V659E Mutation
MA08.09 Clinical Management of Lung Adenocarcinoma Patients With HER2 V659E Mutation Open
View article: P36.02 CHEK1: Unfavourable Prognostic Hub Gene and Potential Therapeutic Target for Lung Adenocarcinoma
P36.02 CHEK1: Unfavourable Prognostic Hub Gene and Potential Therapeutic Target for Lung Adenocarcinoma Open
View article: Novel Compound Heterozygous Mutations in <i>CTSC</i> Gene in a Chinese Family with Papillon-Lefevre Syndrome
Novel Compound Heterozygous Mutations in <i>CTSC</i> Gene in a Chinese Family with Papillon-Lefevre Syndrome Open
Papillon-Lefevre syndrome (PLS) (OMIM: 245000) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early onset periodontitis, resulting in the premature loss of the deciduous and permanent teeth. PLS is …
View article: Gastrointestinal: Papillary cannulation using clip‐attached dental floss traction facilitating endoscopic retrograde cholangiopancreatography with the presence of intradiverticular papilla
Gastrointestinal: Papillary cannulation using clip‐attached dental floss traction facilitating endoscopic retrograde cholangiopancreatography with the presence of intradiverticular papilla Open
Papillary cannulation in the setting of intradiverticular papilla (IDP) during endoscopic retrograde cholangiopancreatography (ERCP) remains challenging for gastrointestinal endoscopists, even for experts. Here we reported a case of common…