Explanipedia

Improving cardiometabolic multimorbidity prediction with a composite obesity–TyG index: a study of middle-aged and older adults in CHARLS Open

Yan Wang, Haonan Wang, Xinyao Liu, Junhui Zhang · 2025

Incidence and Risk Factors of Postoperative Delirium in Children with Congenital Heart Disease: A Retrospective Nationwide Inpatient Sample Database Study Open

Ran An, Jin-Qing Tang, Jing Xu, Hao Xie, Bin Dong , et al. · 2025

Background Postoperative delirium (POD) is an important neurocognitive complication following congenital heart disease (CHD) surgery in pediatric patients. While recognized for its association with adverse clinical outcomes, comprehensive …

The impact of maternal systemic diseases on the occurrence of cleft lip and palate in newborns: a narrative review Open

Hao Sui, Meijun Du, Jiali Chen, Renjie Yang, Bing Shi , et al. · 2025

Cleft lip and palate (CLP) is a prevalent congenital anomaly of the maxillofacial region, characterized by abnormal openings in the lip or palate. This condition, affecting approximately 1 in 700 newborns globally, can manifest as cleft li…

Nurse-led weaning protocols—a systematic review and meta-analysis Open

Yingying Wang, Yan Wang, Shaohua Gu, Li Zhu, Ruizhong Jia , et al. · 2025

Background Research has demonstrated that protocol-directed weaning shortens the duration of mechanical ventilation (MV). Nurse-led weaning protocols have also been suggested to reduce MV duration in patients. Nevertheless, their implement…

Expert consensus on digital restoration of complete dentures Open

Yue Feng, Zhihong Feng, Jing Li, Jihua Chen, Haiyang Yu , et al. · 2025

Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis Open

Chuankai Zhang, Xi Zhang, Yong Ran, Zhihua Wang, Liping Li , et al. · 2025

Artery tertiary lymphoid organs (ATLOs) emerge in atherosclerosis which is a chronic inflammatory artery disease with an autoimmune component. However, whether disease-relevant autoimmune B cells emerge in ATLOs and their impacts remains u…

P-496 Applying serum metabolite profiles for missed miscarriage at early pregnancy Open

Yimin Shi, Qing Li, H. J. Yang, Xingming Guo, Rongshou Zheng , et al. · 2025

Study question Are circulating metabolite profiles different between missed miscarriage (MM) patients and healthy pregnancies (HP)? Summary answer Serum levels of metabolites involved in glutamine metabolism, such as N-acetylglutamine, are…

Shenxiong Yixin Decoction polysaccharides exert therapeutic effects against myocardial ischemia-reperfusion injury via intestinal exosomal microRNA-21 regulation Open

XU De-sheng, Yan Wang, Zirui Li, Pingli Mo, Mingtai Chen , et al. · 2025

SXYXP may protect against MIRI by targeting miR-21 in intestinal cell-derived exosomes, which are transported to the heart through the blood to restore the level of miR-21 in the damaged myocardium, thereby inhibiting oxidative stress and …

The emerging threat of Staphylococcus argenteus: First report from Beijing, China Open

Dianzhe Tian, Diandian Chen, Yunyi Liu, He Lan, Rong Min , et al. · 2025

Digitoflavone Ameliorates Acute Lung Injury via Disturbing the Formation of Functional Stimulator of Interferon Genes Signalosome Open

Junjie Li, Qing Yao, Ming Dong, Yan Wang, Xiu Ye , et al. · 2025

Objective: The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon (IFN) genes (STING) signaling pathway has been implicated in the initiation and maintenance of a variety of inflammatory diseases. Thus, the search for modulators of th…

Predictive Effect of FT3 Within the Euthyroid Range on HDL‐C in Patients With Type 2 Diabetes: A Cross‐Sectional Analysis of Inpatients in China Open

Jinmei Xu, Sihai Zhao, Yan Wang, Jun Han · 2025

Background Evidence for assessing the relationship between free triiodothyronine (FT3) and high‐density lipoprotein cholesterol (HDL‐C) remains limited. Therefore, the purpose of our study is to evaluate the relationship between FT3 and HD…

Comparison of iRoot BP Plus and mineral trioxide aggregate for pulpotomy in primary molars under general anesthesia: a 3-year retrospective study Open

Yiming Zhao, Yuyan Tao, Yan Wang, Jing Zou, Qiong Zhang · 2024

Background Pulpotomy is a widely recommended treatment for deep caries and reversible pulpitis in primary teeth. However, there is a significant lack of large-scale clinical studies evaluating the long-term efficacy of pulpotomy in primary…

Advances in applying somatosensory interaction technology in geriatric care: A bibliometric analysis Open

C. W. Pei, Weibo Lyu, Jingxia Liu, Yan Wang, Wenjia Ye , et al. · 2024

SIT is innovative for promoting active aging, advancing intelligent healthcare, and elevating the daily quality of life for older adults in clinical and domestic settings. Applications of SIT can be categorized into early warning systems f…

The interaction between neutrophils and atrial myocytes in the occurrence and development of atrial fibrillation Open

Tao Li, Yan Wang, Jie Wan, Yu Duan, Yang Xu , et al. · 2024

Spatial-temporal response of the regional ecological quality to urban settlement development Open

Shiwen Zhang, Zhiqiang Zeng, Jianjun Tan, Jinyan Huang, Ranyang Zhang , et al. · 2024

Based on the objective evaluation of the regional ecological quality (Urban Cluster in Mid-inner Zhejiang) by Remote Sensing based Ecological Index (RSEI), it was proposed to study the spatial-temporal response of the regional ecological q…

Partial asynchrony of coniferous forest carbon sources and sinks at the intra-annual time scale Open

Roberto Silvestro, Maurizio Mencuccini, Raúl García‐Valdés, Serena Antonucci, Alberto Arzac , et al. · 2024

The association between dietary, physical activity and the DNA methylation of PPARGC1A, HLA-DQA1 and ADCY3 in pregnant women with gestational diabetes mellitus: a nest case-control study Open

Yan Wang, Jianhua Ren, Biru Luo · 2024

[Multidimensional Social Deprivation Impacts on Frailty in the Elderly: The Mediating Effect of Depression]. Open

Guangquan Ran, Yan Wang, Shuai Liu, Danping Liu · 2024

Social deprivation can influence frailty in elderly people, with depression partially mediating this association.

The prevalence and factors of work-related fatigue among nurses: a meta-analysis and systematic review Open

Rong Pi, Yunfang Liu, Zong De, Yali Wan, Yi Chen , et al. · 2024

Background Numerous studies have evaluated the level of work-related fatigue in nurses and its risk factors. However, none of these studies have rigorously assessed these through meta-analysis and systematic review. Objectives This study a…

Neurodevelopmental outcomes of preterm with necrotizing enterocolitis: a systematic review and meta-analysis Open

Yan Wang, Shunli Liu, Meizhu Lu, Tao Huang, Lan Huang · 2024

While neonatal necrotising enterocolitis (NEC) is associated with high mortality rates in newborns, survivors can face long-term sequelae. However, the relationship between NEC and neurodevelopmental impairment (NDI) in preterm infants rem…

Parents’ experience of children’s transitions from intensive care unit after liver transplantation: A qualitative study Open

Jing‐Yun Wu, Fangyan Lu, Zhi‐Ru Li, Yanhong Dai, Yan Wang , et al. · 2024

This study highlights parents' perspectives on caring for children with liver transplants transferred from the intensive care unit to a general ward. Transitional care is strenuous, evoking different feelings before and after transfer. The…

Initial arch wires used in orthodontic treatment with fixed appliances Open

Chang Liu, Wei Zhi, Fan Jian, Grant T McIntyre, Declan T Millett , et al. · 2024

Superelastic NiTi wires probably produce slightly more pain after one day than thermoelastic NiTi wires, and single-strand superelastic NiTi wires probably have a lower alignment rate over four weeks compared with coaxial superelastic NiTi…

SMU_1361c regulates the oxidative stress response of <i>Streptococcus mutans</i> Open

Shuxing Yu, Qizhao Ma, Jun Huang, Yaqi Liu, Jing Li , et al. · 2024

Dental caries is the most common chronic infectious disease around the world and disproportionately affects the marginalized socioeconomic group. Streptococcus mutans , considered a primary etiological agent of caries, depends on the coord…

Eflornithine for chemoprevention in the high-risk population of colorectal cancer: a systematic review and meta-analysis with trial sequential analysis Open

Lifeng Yang, Yan Wang, Shasha Hu, Xiaoyan Wang · 2023

Objectives To evaluate the efficacy of Difluoromethylornithine (DFMO) chemoprevention in the high-risk population for colorectal cancer (CRC). Methods Meta-analysis was conducted to assess the caliber of the included literature by searchin…

Utilization and Outcome of Abnormal 2PN Human Embryos Open

Hengli Li, Yan Wang, Xudong Shan, Xin Liang, Qingmei Zhao , et al. · 2023

OBJECTIVE There are not a few embryos derived from abnormal 2PN zygotes or embryo. For patients with non-normal available embryos, whether such embryos are discarded or continue to be transplanted have always been a concern of clinicians. …

Clinical validation of near-infrared imaging for early detection of proximal caries in primary molars Open

Jingwei Cao, Yuwen Fang, Yue Liao, Yan Wang, Ran Yang , et al. · 2023

ChiCTR2300070916.

Comparison of dental anesthetic efficacy between the periodontal intraligamentary anesthesia and other infiltration anesthesia: a systematic review and meta-analysis Open

Jialei Pan, Yan Wang, Yuran Qian, Jing Zou, Qiong Zhang · 2023

Background Uncertainty exists regarding the pain scores and the success rate of intraligamentary anesthesia compared to other infiltration anesthesia. Based on the conditions of clinical anesthesia techniques, we conducted a systematic rev…

SMU_1361c regulates the oxidative stress response of<i>Streptococcus mutans</i> Open

Shuxing Yu, Jun Huang, Yaqi Liu, Jing Li, Qiong Zhang , et al. · 2023

Dental caries is the most common chronic infectious diseases around the world and disproportionately affects the marginalized socioeconomic group. Streptococcus mutans , considered a primary etiological agent of caries, must depend on the …

Peer Review #1 of "Neutrophil extracellular trap burden correlates with the stenosis of coronary atherosclerosis (v0.1)" Open

Yan Wang, Mao Yang, Yuanyuan Xu, Shujun Yan, Enze Jin , et al. · 2023

Background.Coronary atherosclerosis diseases (CADs) are associated with chronic inflammation.Neutrophil extracellular traps (NETs) are a type of novel proinflammatory cytokines whose levels are dramatically elevated in acute coronary syndr…

Neutrophil extracellular trap burden correlates with the stenosis of coronary atherosclerosis Open

Yan Wang, Mao Yang, Yuanyuan Xu, Shujun Yan, Enze Jin , et al. · 2023

Background Coronary atherosclerosis diseases (CADs) are associated with chronic inflammation. Neutrophil extracellular traps (NETs) are a type of novel proinflammatory cytokines whose levels are dramatically elevated in acute coronary synd…

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