Yunqing Sun
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View article: Effects of dupilumab on quality of life in patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials
Effects of dupilumab on quality of life in patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials Open
Objective To evaluate the impact of dupilumab treatment on the quality of life, psychological factors and clinical symptoms, in patients with moderate-to-severe atopic dermatitis. Methods A comprehensive search was conducted in PubMed, Web…
View article: Efficacy of mesenchymal stem cells and platelet-rich plasma therapies on wound healing: A Systematic Review and meta-analysis
Efficacy of mesenchymal stem cells and platelet-rich plasma therapies on wound healing: A Systematic Review and meta-analysis Open
The findings from this meta-analysis underscore the promising potential of PRP and MSCs as effective therapeutic strategies for wound healing when used individually.
View article: FAT1 knockdown enhances the CSC properties of HNSCC through p-CaMKII-mediated inactivation of the IFN pathway
FAT1 knockdown enhances the CSC properties of HNSCC through p-CaMKII-mediated inactivation of the IFN pathway Open
FAT atypical cadherin 1 (FAT1), which encodes an atypical cadherin-coding protein, has a high mutation rate and is commonly regarded as a tumor suppressor gene in head and neck squamous cell carcinoma (HNSCC). Nonetheless, the poten…
View article: CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC
CAFs-derived lactate enhances the cancer stemness through inhibiting the MST1 ubiquitination degradation in OSCC Open
Background Cancer-associated fibroblasts (CAFs), a predominant stromal cell type in the tumor microenvironment, significantly affect the progression of oral squamous cell carcinoma (OSCC). Results The specific mechanisms through which CAFs…
View article: EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma
EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma Open
Ephrin receptor A2 (EphA2), a member of the Ephrin receptor family, is closely related to the progression of oral squamous cell carcinoma (OSCC). Cancer stem cells (CSCs) play essential roles in OSCC development and occurrence. The underly…
View article: Bactericidal Antibody Responses to Meningococcal Recombinant Outer Membrane Proteins
Bactericidal Antibody Responses to Meningococcal Recombinant Outer Membrane Proteins Open
Secretin PilQ is an antigenically conserved outer membrane protein that is present in most meningococci and PorA is a major protein that elicits bactericidal immune response in humans following natural disease and immunization. In the pres…
View article: Enhanced lipid biosynthesis in oral squamous cell carcinoma cancer‐associated fibroblasts contributes to tumor progression: Role of <scp>IL8</scp>/<scp>AKT</scp>/<scp>p‐ACLY</scp> axis
Enhanced lipid biosynthesis in oral squamous cell carcinoma cancer‐associated fibroblasts contributes to tumor progression: Role of <span>IL8</span>/<span>AKT</span>/<span>p‐ACLY</span> axis Open
Lipid metabolic reprogramming of tumor cells has been proven to play a critical role in tumor initiation and development. However, lipid metabolism in cancer‐associated fibroblasts (CAFs) has rarely been studied, particularly in CAFs of or…
View article: Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma Open
View article: Mitophagy-Mediated Tumor Dormancy Protects Cancer Cells from Chemotherapy
Mitophagy-Mediated Tumor Dormancy Protects Cancer Cells from Chemotherapy Open
Despite obvious tumor shrinkage, relapse after chemotherapy remains a main cause of cancer-related mortality, indicating that a subpopulation of cancer cells acquires chemoresistance and lingers after treatment. However, the mechanism invo…
View article: Non-Immunoglobin Scaffold Binders as Efficient Affinity Ligands for Purification of Broad-Spectrum Serum Albumins
Non-Immunoglobin Scaffold Binders as Efficient Affinity Ligands for Purification of Broad-Spectrum Serum Albumins Open
View article: Enhanced lipid biosynthesis in OSCC cancer associated fibroblasts contributes to tumor progression: role of IL8/AKT/p-ACLY axis
Enhanced lipid biosynthesis in OSCC cancer associated fibroblasts contributes to tumor progression: role of IL8/AKT/p-ACLY axis Open
Background ATP citrate lygase (ACLY), the key enzyme regulating lipid synthesis, has been proven to play a critical role in tumor initiation and development. However, the roles and relevant mechanisms of ACLY in cancer associated fibroblas…
View article: Fat1 suppresses the CSCs properties through CaMKII-mediated activation of the IFN pathway
Fat1 suppresses the CSCs properties through CaMKII-mediated activation of the IFN pathway Open
FAT atypical cadherin 1 (Fat1), which encodes an atypical cadherin-coding protein, exhibits a high mutation rate and is commonly regarded as a tumor-suppressor gene in head and neck squamous cell carcinoma (HNSCC). Nonetheless, the potenti…
View article: A Review of Gaps between Web 4.0 and Web 3.0 Intelligent Network Infrastructure
A Review of Gaps between Web 4.0 and Web 3.0 Intelligent Network Infrastructure Open
World Wide Web is speeding up its pace into an intelligent and decentralized ecosystem, as seen in the campaign of Web 3.0 and forthcoming Web 4.0. Marked by the Europe Commission's latest mention of Web 4.0, a race towards strategic Web 4…
View article: Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma
Lactate-driven type I collagen deposition facilitates cancer stem cell-like phenotype of head and neck squamous cell carcinoma Open
Background Lactate, the culprit of the acidic tumor microenvironment, is crucial for the therapeutic resistance and metastasis of malignancies. However, the mechanism by which lactate regulates the malignant phenotype of head and neck squa…