Yunshan Cao
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View article: Jugular Venous Catheterization‐Enhanced CT Angiography for In Vivo 3D Visualization of Cardiopulmonary Vasculature in Sprague‐Dawley Rats
Jugular Venous Catheterization‐Enhanced CT Angiography for In Vivo 3D Visualization of Cardiopulmonary Vasculature in Sprague‐Dawley Rats Open
Current in vivo imaging techniques for cardiopulmonary vascular evaluation in Sprague‐Dawley (SD) rats face limitations, including structural disruption, inadequate contrast filling, and invasiveness. This study developed a reliable, minim…
View article: β-Alanine supplementation ameliorates right ventricular remodeling caused by MCT-induced pulmonary hypertension
β-Alanine supplementation ameliorates right ventricular remodeling caused by MCT-induced pulmonary hypertension Open
Background Pulmonary hypertension (PH) is a disease characterized by progressive pulmonary vascular resistance and right heart failure. Beta-alanine (β-Ala), a non-proteinogenic amino acid, exhibits potential cardiovascular benefits; howev…
View article: Delayed lung injury after stent implantation for pulmonary artery stenosis caused by fibrosing mediastinitis
Delayed lung injury after stent implantation for pulmonary artery stenosis caused by fibrosing mediastinitis Open
View article: Spontaneous Enlargement in Balloon Pulmonary Angioplasty With Undersized Balloon for Chronic Thromboembolic Pulmonary Hypertension
Spontaneous Enlargement in Balloon Pulmonary Angioplasty With Undersized Balloon for Chronic Thromboembolic Pulmonary Hypertension Open
Background Balloon pulmonary angioplasty (BPA) has emerged as an effective treatment for chronic thromboembolic pulmonary hypertension (CTEPH). Recent studies have reported progressive improvements in hemodynamic and clinical parameters du…
View article: Machine learning–based hemodynamics quantitative assessment of pulmonary circulation using computed tomographic pulmonary angiography
Machine learning–based hemodynamics quantitative assessment of pulmonary circulation using computed tomographic pulmonary angiography Open
This study provides a noninvasive method for comprehensively and quantitatively evaluating pulmonary hemodynamics using CTPA images, which has the potential to serve as an alternative to RHC, pending further validation.
View article: Safety and Efficacy of Half-Half Inflation Strategy in Pulmonary Artery Stenosis Caused by Fibrosing Mediastinitis
Safety and Efficacy of Half-Half Inflation Strategy in Pulmonary Artery Stenosis Caused by Fibrosing Mediastinitis Open
View article: Role of a New Walk Test in Pulmonary Arterial Hypertension: A Retrospective Cohort Study
Role of a New Walk Test in Pulmonary Arterial Hypertension: A Retrospective Cohort Study Open
The 6‐min walk test (6MWT) has significant prognostic value, but requires long walking distances and lacks evaluation of exercise speed. This study aimed to investigate the clinical utility of a new walk test, the 18‐meter walk test (18MWT…
View article: Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis
Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis Open
Pulmonary hypertension (PH) often leads to poor survival outcomes and encompasses diverse subtypes with distinct underlying causes. Specifically, PH resulting from fibrosing mediastinitis (FM‐PH) presents significant diagnostic challenges …
View article: Percutaneous stenting for multifaceted fibrosing mediastinitis with multivessel involvement
Percutaneous stenting for multifaceted fibrosing mediastinitis with multivessel involvement Open
View article: Image Findings from Dual-phase Computed Tomography Pulmonary Angiography for Diagnosing Tuberculosis-associated Fibrosing Mediastinitis
Image Findings from Dual-phase Computed Tomography Pulmonary Angiography for Diagnosing Tuberculosis-associated Fibrosing Mediastinitis Open
Objective: Fibrosing mediastinitis (FM) is a rare and benign disease affecting the mediastinum and often causes pulmonary hypertension (PH). Timely diagnosis of PH caused by FM is clinically important to mitigate complications such as righ…
View article: Incidence and predictors of in-stent restenosis following intervention for pulmonary vein stenosis due to fibrosing mediastinitis
Incidence and predictors of in-stent restenosis following intervention for pulmonary vein stenosis due to fibrosing mediastinitis Open
Background Fibrosing mediastinitis (FM) is a rare yet fatal condition, caused by different triggers and frequently culminating in the obstruction of the pulmonary vasculature and airways, often leading to pulmonary hypertension and right h…
View article: Low-lying magnon frequency comb in skymion crystals
Low-lying magnon frequency comb in skymion crystals Open
A stable, low-power and tunable magnon frequency comb (MFC) is crucial for magnon-based precision measurements, quantum information processing and chip integration. Original method for creating MFC utilizes the nonlinear interactions betwe…
View article: Real-world effectiveness and safety of macitentan in patients with pulmonary artery hypertension: a multicenter, retrospective, observational study in China
Real-world effectiveness and safety of macitentan in patients with pulmonary artery hypertension: a multicenter, retrospective, observational study in China Open
This study provided real-world evidence on the clinical benefits and good tolerance of macitentan in Chinese patients with PAH treated in routine clinical practice.
View article: Regulatory roles of RNA methylation in vascular lesions in ocular and cardiopulmonary diseases
Regulatory roles of RNA methylation in vascular lesions in ocular and cardiopulmonary diseases Open
RNA methylation is a widespread regulatory mechanism that controls gene expression in physiological processes. In recent years, the mechanisms and functions of RNA methylation under diseased conditions have been increasingly unveiled by RN…
View article: A young woman presenting with dyspnoea and diffuse T-wave inversions: a case report
A young woman presenting with dyspnoea and diffuse T-wave inversions: a case report Open
Background T-wave inversions on electrocardiograms (ECGs) indicate a variety of conditions, such as coronary artery disease, myocarditis, and cardiomyopathy. Pulmonary artery stenosis (PAS) and pulmonary hypertension (PH) may cause right v…
View article: Venous retrograde approach for endovascular angioplasty in chronic total pulmonary vein occlusion -a case report
Venous retrograde approach for endovascular angioplasty in chronic total pulmonary vein occlusion -a case report Open
Introduction Fibrosing mediastinitis (FM) is a rare disease characterized by excessive proliferation of fibrous tissue in the mediastinum and can cause bronchial stenosis, superior vena cava obstruction, pulmonary artery and vein stenosis,…
View article: Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension Open
Background Patients with pulmonary hypertension (PH) and chronic obstructive pulmonary disease (COPD) have an increased risk of disease exacerbation and decreased survival. We aimed to develop and validate a non‐invasive nomogram for predi…
View article: Comparison of clopidogrel and ticagrelor in treating acute coronary syndrome undergoing PCI: A systematic review and meta-analysis
Comparison of clopidogrel and ticagrelor in treating acute coronary syndrome undergoing PCI: A systematic review and meta-analysis Open
PROSPERO registration number CRD42021274198.
View article: False Subarachnoid Hemorrhage: A Deceptive Presentation of Subarachnoid Hemorrhage
False Subarachnoid Hemorrhage: A Deceptive Presentation of Subarachnoid Hemorrhage Open
This case presents a special case of an 83-year-old female who had a pseudo-subarachnoid hemorrhage following a thrombectomy for acute cerebral infarction. Head computed tomography (CT) showed imaging revealed findings consistent with suba…
View article: Pulmonary vascular stenosis scoring in fibrosing mediastinitis
Pulmonary vascular stenosis scoring in fibrosing mediastinitis Open
Aims This study aims to develop a scoring system for evaluating the degree of pulmonary vascular stenosis in fibrosing mediastinitis (FM). Methods and results A retrospective single-centre study was conducted on 56 patients with FM in Chin…
View article: Risk Stratification and Prognosis of Pulmonary Arterial Hypertension Associated with Congenital Heart Disease
Risk Stratification and Prognosis of Pulmonary Arterial Hypertension Associated with Congenital Heart Disease Open
Background: Current guidelines for managing pulmonary arterial hypertension (PAH) recommend a risk stratification approach. However, the applicability and accuracy of these strategies for PAH associated with congenital heart disease…
View article: A rare sequelae of esophageal perforation: Fibrosing mediastinitis
A rare sequelae of esophageal perforation: Fibrosing mediastinitis Open
Fibrosing mediastinitis (FM) is a rare disease caused by different causes. If left untreated, the prognosis is poor. The common causes of FM are Tuberculosis and Histoplasma capsulatum infection. Esophageal perforation is also a rare condi…
View article: Fibrosing mediastinitis triangle
Fibrosing mediastinitis triangle Open
An uncommon disorder known as fibrosing mediastinitis (FM) is characterized by proliferative fibrotic tissues compressing pulmonary artery, bronchus, and pulmonary vein. If left untreated, FM can be deadly. It is typical for people to be m…
View article: Magnon Hall effect
Magnon Hall effect Open
Hall effect is an ancient but highly potential subfield in condensed matter physics, and its origin can be traced back hundreds of years. In 1879, Hall made a momentous discovery that when a current-carrying conductor is placed in a magnet…
View article: Chronic Pulmonary Artery Stenosis: Time to Think as a Disease Entity
Chronic Pulmonary Artery Stenosis: Time to Think as a Disease Entity Open
Chronic pulmonary artery stenosis (CPAS) is characterized by a reduction or complete obstruction of the cross-sectional area of the pulmonary artery owing to various causes. The condition exhibits similar pathophysiological progress, leadi…
View article: Incidence and Predictors of In-stent Restenosis Following Intervention for Pulmonary Vein Stenosis due to Fibrosing Mediastinitis
Incidence and Predictors of In-stent Restenosis Following Intervention for Pulmonary Vein Stenosis due to Fibrosing Mediastinitis Open
Background Percutaneous transluminal pulmonary venoplasty (PTPV) is an emerging treatment for pulmonary vein stenosis (PVS) caused by fibrosing mediastinitis (FM). However, the incidence and predictors of in-stent restenosis (ISR) are elus…
View article: Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia
Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia Open
Myopia is a major public health issue. However, interventional modalities for nonpathologic myopia are limited due to its complicated pathogenesis and the lack of precise targets. Here, we show that in guinea pig form-deprived myopia (FDM)…
View article: Exosomes derived from HIF-1α modified adipose mesenchymal stem cell- ameliorates pulmonary vascular remodeling via upregulating FOXO1 in mice with pulmonary hypertension
Exosomes derived from HIF-1α modified adipose mesenchymal stem cell- ameliorates pulmonary vascular remodeling via upregulating FOXO1 in mice with pulmonary hypertension Open
Increasing evidence suggests that adipose mesenchymal stem cells (ADSCs) execute their paracrine effects via the secretion of exosomes, especially under hypoxic conditions. HIF-1α played a critical role in regulating the cellular response …
View article: Progress in the Metabolomics of Acute Coronary Syndrome
Progress in the Metabolomics of Acute Coronary Syndrome Open
Acute coronary syndrome (ACS) is a severe type of coronary heart disease (CHD) with increasing prevalence and significant challenges for prevention and treatment. Metabolomics is an emerging technology with intrinsic dynamics and flexibili…
View article: Pulmonary Vein Stenosis: A Review
Pulmonary Vein Stenosis: A Review Open
Pulmonary vein stenosis (PVS) is an extremely rare and lethal disease caused by multiple etiologies. PVS has a bimodal distribution in the population, affecting children and adults. Congenital PVS is the usual PVS type in children, which s…