Explanipedia

A multiplex assay with 21 single nucleotide polymorphisms for commercial Eucalyptus clones identification Open

Jingyi Zhao, Siming Gan, Qizheng Weng, Youjun Wu, Changpin Zhou · 2025

Eucalyptus is the most widely cultivated hardwoodacross tropical, sub-tropical and temperate regions worldwide. However, with successive generations of tissue culture and the rapid expansion of plantations, clone mislabeling and quality de…

Effectiveness of Virtual Reality-Based Early Rehabilitation Strategies on Pain, Sleep, Anxiety, Balance, Cognition, and Quality of Life in Adult ICU Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (Preprint) Open

Fei Wu, Youjun Wu, Yana Xing, Ran Zhang, Weixin Cai · 2025

BACKGROUND Early rehabilitation strategies based on virtual reality (VR) technology offer a new perspective for the physical, psychological, and cognitive rehabilitation of critically ill patients, yet there are still discrepancies in the…

Optimizing Bromine Complexation and Kinetics: a Bisimidazole Strategy for High‐Performance Zn‐Br Static Batteries Open

Youjun Wu, Xu Chen, Chengjun Lei, Wenjiao Ma, Wei Zhang , et al. · 2025

Zinc–bromine (Zn–Br) static batteries are promising for large‐scale energy storage, yet the practical application is hindered by the long‐standing trade‐off about bromine complexing agents (BCAs) between bromine complexation strength and r…

FOXM1 boosts glycolysis by upregulating SQLE to inhibit anoikis in breast cancer cells Open

Mei Xu, Guoyuan Pan, Qian Zhang, Jiangming Huang, Youjun Wu , et al. · 2025

Bipolar Carbazole/Quinoxaline-Based Host Materials with High Efficiency in Red Phosphorescence Oleds Open

Yeliang Jiang, Zixing Wang, Youjun Wu, Panpan Zang, Peng Wu · 2025

Cytoplasmic ribosomes hitchhike on mitochondria to dendrites Open

Corbin J Renken, Susie Kim, Youjun Wu, Marc Hammarlund, Shaul Yogev · 2024

Neurons rely on local protein synthesis to rapidly modify the proteome of neurites distant from the cell body. A prerequisite for local protein synthesis is the presence of ribosomes in the neurite, but the mechanisms of ribosome transport…

Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency Open

Haoming Wang, John Vant, Andrew Zhang, Richard G. Sánchez, Youjun Wu , et al. · 2024

Glucose, the primary cellular energy source, is metabolized through glycolysis initiated by the rate-limiting enzyme hexokinase (HK). In energy-demanding tissues like the brain, HK1 is the dominant isoform, primarily localized on mitochond…

Linker aggregation engineering of TADF materials to tune carrier balance for highly efficient organic LEDs with long operational lifetime Open

Zhen Zhang, Rongrong Xia, Ke Wang, Youjun Wu, Panpan Zang , et al. · 2024

Thermally activated delayed fluorescence (TADF) molecules are regarded as promising materials for realizing high‐performance organic light‐emitting diodes (OLEDs). The connecting groups between donor (D) and acceptor (A) units in D–A type …

Current knowledge of ferroptosis in the pathogenesis and prognosis of oral squamous cell carcinoma Open

Liyuan Zhou, Youjun Wu, Yukang Ying, Yan Ding · 2024

Therapeutic strategies are the hot-spot issues in treating patients with advanced oral squamous cell carcinoma (OSCC). Mounting studies have proved that triggering ferroptosis is one of the promising targets for OSCC management. In this st…

Generation of human cerebral organoids with a structured outer subventricular zone Open

Ryan Walsh, Raffaele Luongo, Elisa Giacomelli, Gabriele Ciceri, Chelsea Rittenhouse , et al. · 2024

Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport Open

Youjun Wu, Chen Ding, Behrang Sharif, Alexis Weinreb, Grace Swaim , et al. · 2024

Mitochondria transport is crucial for axonal mitochondria distribution and is mediated by kinesin-1-based anterograde and dynein-based retrograde motor complexes. While Miro and Milton/TRAK were identified as key adaptors between mitochond…

CCDC 2291725: Experimental Crystal Structure Determination Open

Rongrong Xia, Zhen Zhang, Peng Wu, Youjun Wu, Ke Wang , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans Open

Oliver Glomb, Grace Swaim, Pablo Munoz LLancao, Christopher Lovejoy, Sabyasachi Sutradhar , et al. · 2023

Protocol for the design, conduct, and evaluation of prime editing in human pluripotent stem cells Open

Youjun Wu, Mega Sidharta, Aaron Zhong, Benjamin Persily, Mu Li , et al. · 2023

Prime editing introduces single-nucleotide polymorphism changes, small deletions, or insertions at a specific genome site without double-stranded DNA breaks or the need for the donor template. Here, we present a protocol to design, conduct…

Functional Organization of Glycolytic Metabolon on Mitochondria Open

Haoming Wang, John Vant, Youjun Wu, Richard G. Sánchez, Mary Lauren Micou , et al. · 2023

SUMMARY Glucose, the primary cellular energy source, is metabolized through glycolysis initiated by the rate-limiting enzyme Hexokinase (HK). In energy-demanding tissues like the brain, HK1 is the dominant isoform, primarily localized on m…

Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport Open

Youjun Wu, Chen Ding, Alexis Weinreb, Laura Manning, Grace Swaim , et al. · 2023

Mitochondria transport is crucial for mitochondria distribution in axons and is mediated by kinesin-1-based anterograde and dynein-based retrograde motor complexes. While Miro and Milton/TRAK were identified as key adaptors between mitocho…

Generation of human cerebral organoids with a structured outer subventricular zone Open

Ryan Walsh, Elisa Giacomelli, Gabriele Ciceri, Chelsea Rittenhouse, Maura Galimberti , et al. · 2023

Summary Mammalian outer radial glia (oRG) emerge as cortical progenitor cells that directly support the development of an enlarged outer subventricular zone (oSVZ) and, in turn, the expansion of the neocortex. The in vitro generation of oR…

An Evaluation of Laminarin Additive in the Diets of Juvenile Largemouth Bass (Micropterus salmoides): Growth, Antioxidant Capacity, Immune Response and Intestinal Microbiota Open

Youjun Wu, Yan Cheng, Shichao Qian, Wei Zhang, Mengmeng Huang , et al. · 2023

A 28 day feeding trial was conducted to investigate the growth performance, immune response and intestinal microbiota of laminarin (LAM) supplemented diets in juvenile largemouth bass (Micropterus salmoides). Four hundred and eighty fish (…

Effect of Height-to-Diameter Ratio on the Compression Test Results of Remodeled Loess and Its Mechanism Open

Wang Yao, Xian Li, Youjun Wu, Quan Xue, Zhitao Hao , et al. · 2023

The confined compression test is the most widely used test to study the compressive deformation of soil in a laboratory, and the height–diameter (H/D) ratio has a significant effect on the confined compression test results. However, there …

Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells Open

Mu Li, Aaron Zhong, Youjun Wu, Mega Sidharta, Michael W. Beaury , et al. · 2022

[MiR-372-5p regulates PI3K/AKT/CXCL12 signaling pathway by targeting PTEN to promote colorectal cancer cell metastasis]. Open

Xiaoyan Shi, K Wei, Youjun Wu, W Wang, Qing Yang , et al. · 2022

MiR-372-5p activates PI3K/AKT signaling pathway by targeting PTEN and up-regulates CXCL12 expression to promoting metastasis of colorectal cancer cells.

miR-3942-3p Increases the radiosensitivity of nasopharyngeal carcinoma through negatively regulating BARD1 Open

Luxing Peng, Jiaxin Chen, Heming Lu, Jinjian Cheng, Qiang Pang , et al. · 2022

Nasopharyngeal carcinoma (NPC) has high incidence in China and East and Southeast Asia. The study was performed to investigate the effect of microRNA3942-3p (miR-3942-3p) on the radiosensitivity of NPC. Compared with non-cancer tissue, NPC…

Scaled-expansion of the membrane associated cytoskeleton requires conserved kinesin adaptors Open

Oliver Glomb, Grace Swaim, Pablo Munoz LLancao, Christopher Lovejoy, Sabyasachi Sutradhar , et al. · 2022

A periodic lattice of actin rings and spectrin tetramers scaffolds the axonal membrane. How spectrin is delivered to this structure to scale its size to that of the growing axon is unknown. We found that endogenous spectrin, visualized wit…

Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria Open

Chen Ding, Youjun Wu, Hadas Dabas, Marc Hammarlund · 2022

Mitochondrial defects are tightly linked to axon degeneration, yet the underlying cellular mechanisms remain poorly understood. In Caenorhabditis elegans, PVQ axons that lack mitochondria degenerate spontaneously with age. Using an unbiase…

Author response: Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria Open

Chen Ding, Youjun Wu, Hadas Dabas, Marc Hammarlund · 2021

Article Figures and data Abstract Editor's evaluation eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Mitochond…

Activation of the CaMKII-Sarm1-ASK1 MAP kinase pathway protects against axon degeneration caused by loss of mitochondria Open

Chen Ding, Youjun Wu, Hadas Dabas, Marc Hammarlund · 2021

Mitochondrial defects are tightly linked to axon degeneration, yet the underlying cellular mechanisms remain poorly understood. In C. elegans, PVQ axons that lack mitochondria degenerate spontaneously with age. Using an unbiased genetic sc…

Long-Term Results of Concurrent Chemoradiotherapy Combined With Anti-EGFR Monoclonal Antibody Prior to Surgery in Locally Advanced Cervical Cancer: A Single Institute Prospective Study Open

Youjun Wu, Defeng Qing, Heming Lu, X. Liu, Haijun Jiang , et al. · 2020

Directly Electrospun Carbon Nanofibers Incorporated with Mn3O4 Nanoparticles as Bending-Resistant Cathode for Flexible Al-Air Batteries Open

Ying Yu, Yuxin Zuo, Ying Liu, Youjun Wu, Zhonghao Zhang , et al. · 2020

Al-air batteries are regarded as potential power source for flexible and wearable devices. However, the traditional cathodes of Al-air batteries are easy to be broken after continuous bending. This is why few Al-air batteries have been tes…

Clinical characteristics of colorectal cancer patients and anti-neoplasm activity of genistein Open

Xiaoyu Chen, J. Gu, Youjun Wu, Ping Liang, Meichen Shen , et al. · 2020

A Small Molecule-Controlled Cas9 Repressible System Open

Youjun Wu, Lu Yang, Tammy T. Chang, Fouad Kandeel, Jiing‐Kuan Yee · 2020

Youjun Wu YOU? Author Swipe